Huntington's Disease News and Research

Latest Huntington's Disease News and Research

New guidelines developed for effective management of neuropsychiatric symptoms of Huntington’s disease

Although Huntington's disease (HD) is traditionally thought of as a neurological disorder, behavioral symptoms are a common feature and frequently cause distress and difficulty to patients, family members, and other caregivers.

30 Jan 2019

Simple blood test reliably detects signs of Alzheimer’s damage before symptoms

A simple blood test reliably detects signs of brain damage in people on the path to developing Alzheimer's disease - even before they show signs of confusion and memory loss, according to a new study from Washington University School of Medicine in St. Louis and the German Center for Neurodegenerative Diseases in Germany.

21 Jan 2019

New method to speed up genetic diagnosis of Huntington’s disease

Elongated segments of DNA cause Huntington's disease and certain other disorders of the brain. Researchers funded by the SNSF have developed a method to determine the length of the mutated genes quickly and easily.

10 Jan 2019

Neuronal cell death in Alzheimer's disease may actually not be a bad thing, shows study

For the first time, scientists at the Champalimaud Centre for the Unknown, in Lisbon, Portugal, have shown that neuronal cell death in Alzheimer's disease may actually not be a bad thing - on the contrary, it may be the result of a cell quality control mechanism trying to protect the brain from the accumulation of malfunctioning neurons.

27 Dec 2018

NIPER researcher presents a review on autophagy in neuronal cells

Autophagy is a cellular degradation process that can cause the death of a cell in certain conditions. Autophagy is necessary to maintain cellular homeostasis by clearing out damaged cellular organelles and proteins through certain pathways.

27 Dec 2018

New mechanism may explain neurons shrinking in Huntington's disease

A hallmark of neurodegenerative diseases like Huntington's is the progressive death of nerve cells in the brain. The cells don't die quickly, though. They first start to disconnect from each other because their neurites -- long finger-like extensions that make connections all through the brain -- become smaller.

25 Dec 2018

Glial cell maturation is severely impaired in patients with Huntington's disease

The neurological disorder Huntington's disease causes behavioral and motor changes, which among other things are a result of dysfunctional maturation or formation of glial cells, the brain's support cells, researchers from the University of Copenhagen demonstrate in a new study based on mice trials.

24 Dec 2018

Study finds epigenetic differences in the brains of individuals with schizophrenia

A study using a PET scan tracer developed at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital has identified, for the first time, epigenetic differences between the brains of individuals with schizophrenia and those of unaffected study participants.

17 Dec 2018

New research lays out potential path for treatment of Huntington’s disease

New research gives scientists a clearer picture of what is happening in the brains of people with Huntington's disease and lays out a potential path for treatment.

14 Dec 2018

Intellectually active lifestyle confers protection against neurodegeneration in Huntington's patients

Researchers from the Cognition and Brain Plasticity research group of the Bellvitge Biomedical Research Institute and the University of Barcelona, in collaboration with several hospitals, have discovered that an intellectually active lifestyle confers protection against neurodegeneration in people with Huntington's disease, delaying the onset of symptoms and loss of grey matter in the brain.

12 Dec 2018

Antibiotic-resistant bacteria could soon be targeted with Alzheimer's drug

Dangerous antibiotic-resistant bacteria could soon be targeted with a drug initially developed to treat Alzheimer's disease.

12 Dec 2018

Mount Sinai researcher awarded $2.5 million to advance understanding of neurodegenerative diseases

Ivan Marazzi, PhD, Assistant Professor of Microbiology at the Icahn School of Medicine at Mount Sinai, was awarded $2.5 million in funding by the Chan Zuckerberg Initiative to further the understanding of the underlying causes of neurodegenerative disorders such as Lou Gehrig's, Alzheimer's, and Parkinson's diseases. The

7 Dec 2018

CZI announces over $51 million funding to fight neurodegenerative diseases

Today, the Chan Zuckerberg Initiative announced $64.25 million in funding and its selection of 17 early career investigators and nine collaborative science teams to launch the CZI Neurodegeneration Challenge Network

5 Dec 2018

First bifacial molecule can invade double-stranded DNA or RNA

Carnegie Mellon University researchers have developed a synthetic molecule that can recognize and bind to double-stranded DNA or RNA under normal physiological conditions. The molecule could provide a new platform for developing methods for the diagnosis and treatment of genetic conditions.

13 Nov 2018

C-Path, CHDI and CDISC announce availability of Huntington's Disease Therapeutic Area User Guide

The Huntington's Disease Regulatory Science Consortium, launched in March 2018 by the Critical Path Institute and CHDI Foundation, today, along with the Clinical Data Interchange Standards Consortium, announce the open availability of a newly developed Huntington's Disease Therapeutic Area User Guide

2 Nov 2018

New form of therapy may stop or reverse progressive vision loss

A new form of therapy may halt or even reverse a form of progressive vision loss that, until now, has inevitably led to blindness.

1 Nov 2018

Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation

A group of Massachusetts General Hospital investigators is proposing that targeting immune checkpoints - molecules that regulate the activity of the immune system - in immune cells called microglia could reduce the inflammatory aspects of important neurodegenerative diseases like Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis.

17 Oct 2018

Genentech announces clinical data from studies investigating risdiplam in spinal muscular atrophy

Genentech, a member of the Roche Group, announced today interim clinical data from the dose-finding parts of the pivotal FIREFISH and SUNFISH studies investigating risdiplam in spinal muscular atrophy.

3 Oct 2018

Blood-brain barrier can be important biomarker for early diagnosis of Alzheimer's disease

USC scientists say Alzheimer's could be diagnosed earlier if scientists focus on an early warning within the brain's circulation system.

25 Sep 2018

Penn researchers find common thread linking almost all TNR expansion diseases

In a class of roughly 30 neurological disorders that includes ALS, Huntington's Disease and Fragile X Syndrome, the relevant mutant gene features sections of repeating base pair sequences known as short tandem repeats, or STRs. Healthy people have STRs of normal lengths distributed across their DNA.

19 Sep 2018

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

New guidelines developed for effective management of neuropsychiatric symptoms of Huntington’s disease

Simple blood test reliably detects signs of Alzheimer’s damage before symptoms

New method to speed up genetic diagnosis of Huntington’s disease

Neuronal cell death in Alzheimer's disease may actually not be a bad thing, shows study

NIPER researcher presents a review on autophagy in neuronal cells

New mechanism may explain neurons shrinking in Huntington's disease

Glial cell maturation is severely impaired in patients with Huntington's disease

Study finds epigenetic differences in the brains of individuals with schizophrenia

New research lays out potential path for treatment of Huntington’s disease

Intellectually active lifestyle confers protection against neurodegeneration in Huntington's patients

Antibiotic-resistant bacteria could soon be targeted with Alzheimer's drug

Mount Sinai researcher awarded $2.5 million to advance understanding of neurodegenerative diseases

CZI announces over $51 million funding to fight neurodegenerative diseases

First bifacial molecule can invade double-stranded DNA or RNA

C-Path, CHDI and CDISC announce availability of Huntington's Disease Therapeutic Area User Guide

New form of therapy may stop or reverse progressive vision loss

Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation

Genentech announces clinical data from studies investigating risdiplam in spinal muscular atrophy

Blood-brain barrier can be important biomarker for early diagnosis of Alzheimer's disease

Penn researchers find common thread linking almost all TNR expansion diseases

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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