Immunology News and Research

Latest Immunology News and Research

Novel antibodies can aid in early diagnosis of Sjogren's Syndrome

Patients suffering from the painful autoimmune disease, Sjogren's Syndrome, will soon be able to be properly diagnosed much earlier, thanks to the discovery of novel antibodies by researchers at the University at Buffalo and Immco Diagnostics, Inc. The breakthrough, described in a paper in the December issue of Clinical Immunology, will allow patients to be treated sooner when they are much more likely to benefit.

14 Dec 2012

SLU researchers to study physiological and biochemical functions in lupus

Two researchers at Saint Louis University's division of rheumatology in the department of internal medicine have been awarded a $1.8 million NIH grant to study the physiological and biochemical functions in lupus, an autoimmune disease, and develop possible new medications for its treatment.

14 Dec 2012

HPV in women at or after menopause may represent an infection acquired years ago

A new study suggests that human papillomavirus (HPV) infection in women at or after menopause may represent an infection acquired years ago, and that HPV infections may exist below limits of detection after one to two years, similar to other viruses, such as varicella zoster, which can cause shingles.

14 Dec 2012

Scientists identify new mutation in a gene that causes Alpha-1 Antitrypsin Deficiency

Scientists have identified a new mutation in the gene that causes the inherited disease known as Alpha-1 Antitrypsin Deficiency (Alpha-1), which affects roughly one in 2,500 people of European descent.

14 Dec 2012

Heartbeat Experts announces increased revenue and expanded clients in emerging markets

Heartbeat Experts, the global leader in stakeholder management solutions for the life sciences industry, announced today increased revenue and expanded clients across Brazil, Russia, China, India and Korea. Heartbeat Experts' reported combined revenue from these markets grew 50% in the third quarter of 2012.

13 Dec 2012

CRI, SU2C form Cancer Immunology Translational Research Dream Team

Stand Up To Cancer (SU2C) and the Cancer Research Institute (CRI) announce the formation of a Dream Team project dedicated to cancer immunology - "Immunologic Checkpoint Blockade and Adoptive Cell Transfer in Cancer Therapy."

13 Dec 2012

Patients with multiple sclerosis have low levels of Egr2/3 protein in T lymphocytes

Researchers from Queen Mary, University of London have discovered that two proteins which are believed to play a key role in controlling the body's immune response are found in lower levels in T lymphocytes from patients with multiple sclerosis (MS).

13 Dec 2012

Dantrolene may help combat Duchenne muscular dystrophy in boys

Drugs are currently being tested that show promise in treating patients with Duchenne muscular dystrophy (DMD), an inherited disease that affects about one in 3,600 boys and results in muscle degeneration and, eventually, death.

13 Dec 2012

Researchers discover a trigger by which the HCV enters liver cells

Researchers at the University of Southern California (USC) have discovered a trigger by which the Hepatitis C virus enters liver cells ─ shedding light on how this serious and potentially deadly virus can begin to damage the liver.

13 Dec 2012

TKI-resistant human leukemia stem cells are the source of genomic instability

An international team of scientists, led by researchers from Temple University School of Medicine, has found that a source of mounting genomic chaos, or instability, common to chronic myeloid leukemia (CML) may lie in a pool of leukemia stem cells that are immune to treatment with potent targeted anticancer drugs.

12 Dec 2012

Edith and Peter O'Donnell Awards to recognize Texas researchers on Jan.17

The Academy of Medicine, Engineering, and Science of Texas (TAMEST) is pleased to announce the recipients of the 2013 Edith and Peter O'Donnell Awards who will be honored during a banquet on Thursday, January 17, 2013, in conjunction with TAMEST's 10th Annual Conference at the Westin Galleria Hotel in Dallas.

12 Dec 2012

Study finds important links between Pf malaria and endemic Burkitt Lymphoma

New research, presented this morning at the 54th Annual Meeting of the American Society of Hematology (ASH), has identified important associations between Plasmodium falciparum (Pf) malaria and endemic Burkitt Lymphoma (eBL) that may help researchers identify young children who are more susceptible to eBL.

12 Dec 2012

New collaborative model for drug discovery can ensure antibiotics are not lost to resistance

Noting "multidrug-resistant organisms are showing up in top-flight hospitals" around the world, Carl Nathan, chair of the department of microbiology and immunology at Weill Cornell Medical College, writes in this New York Times opinion piece, "What makes the rapid loss of antibiotics to drug resistance particularly alarming is that we are failing to make new ones."

12 Dec 2012

Blocking myeloid-derived suppressor cells after lymphopenia improves adoptive T-cell therapy

Researchers at the Moffitt Cancer Center have found that delayed tumor growth and enhanced survival of mice bearing melanoma were possible by blocking the reconstitution of myeloid-derived suppressor cells and Tregs (suppressors of anti-tumor activity) after total body irradiation had eliminated them. Blocking myeloid-derived suppressor cells and regulatory T-cell reconstitution improved adoptive T-cell therapy, an immunotherapy designed to suppress tumor activity.

12 Dec 2012

Astellas, FibroGen commence FG-4592/ASP1517 Phase 3 clinical program in CKD anemia

FibroGen, Inc., and Astellas Pharma Inc., announced today the initiation of the first clinical study in the Phase 3 clinical development program of FG-4592/ASP1517, an orally administered small molecule, for treatment of anemia associated with chronic kidney disease ("CKD") in patients not on dialysis and on dialysis, to support approval in the U.S. and Europe.

12 Dec 2012

Two UT Southwestern researchers to receive 2013 Edith and Peter O'Donnell Award

The Academy of Medicine, Engineering, and Science of Texas (TAMEST) announced that two UT Southwestern Medical Center researchers are among the four chosen for the 2013 Edith and Peter O'Donnell Awards.

12 Dec 2012

Bacteriophages may play an important role in competition among bacterial strains

Unique viruses called bacteriophages may play an important role in competition among bacterial strains, influencing the overall ecosystem of the human intestine, scientists at The University of Texas at Arlington and UT Southwestern Medical Center say.

11 Dec 2012

Astellas, Ambit announce results from quizartinib Phase 2 study on acute myeloid leukemia

Astellas Pharma Inc. and Ambit Biosciences Corporation announced today that the results from a completed Phase 2 study with the investigational FLT3 inhibitor, quizartinib (AC220), as an oral monotherapy treatment regimen in patients with relapsed or refractory acute myeloid leukemia (AML) were presented at the 54th Annual Meeting of the American Society of Hematology (ASH).

11 Dec 2012

Intensified chemotherapy can reduce risk of relapse in pediatric patients with B-ALL

Young patients with an aggressive form of leukemia who are likely to relapse after chemotherapy treatment can significantly reduce those odds by receiving additional courses of chemotherapy, suggest the findings of a clinical trial led by investigators at Dana-Farber/Children's Hospital Cancer Center in Boston.

11 Dec 2012

Preliminary results from Boehringer Ingelheim’s volasertib Phase II study on AML

Boehringer Ingelheim Pharmaceuticals, Inc. today reported preliminary results from the randomized Phase II part of a Phase I/II study involving the company's investigational compound volasertib in newly diagnosed patients with acute myeloid leukemia (AML) considered ineligible for intensive remission induction therapy.

11 Dec 2012

Immunology News and Research

Latest Immunology News and Research

Novel antibodies can aid in early diagnosis of Sjogren's Syndrome

SLU researchers to study physiological and biochemical functions in lupus

HPV in women at or after menopause may represent an infection acquired years ago

Scientists identify new mutation in a gene that causes Alpha-1 Antitrypsin Deficiency

Heartbeat Experts announces increased revenue and expanded clients in emerging markets

CRI, SU2C form Cancer Immunology Translational Research Dream Team

Patients with multiple sclerosis have low levels of Egr2/3 protein in T lymphocytes

Dantrolene may help combat Duchenne muscular dystrophy in boys

Researchers discover a trigger by which the HCV enters liver cells

TKI-resistant human leukemia stem cells are the source of genomic instability

Edith and Peter O'Donnell Awards to recognize Texas researchers on Jan.17

Study finds important links between Pf malaria and endemic Burkitt Lymphoma

New collaborative model for drug discovery can ensure antibiotics are not lost to resistance

Blocking myeloid-derived suppressor cells after lymphopenia improves adoptive T-cell therapy

Astellas, FibroGen commence FG-4592/ASP1517 Phase 3 clinical program in CKD anemia

Two UT Southwestern researchers to receive 2013 Edith and Peter O'Donnell Award

Bacteriophages may play an important role in competition among bacterial strains

Astellas, Ambit announce results from quizartinib Phase 2 study on acute myeloid leukemia

Intensified chemotherapy can reduce risk of relapse in pediatric patients with B-ALL

Preliminary results from Boehringer Ingelheim’s volasertib Phase II study on AML

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