Immunology News and Research

Latest Immunology News and Research

IL-13 receptor system could play a major role in Parkinson's

Deciphering what causes the brain cell degeneration of Parkinson's disease has remained a perplexing challenge for scientists. But a team led by scientists from The Scripps Research Institute (TSRI) has pinpointed a key factor controlling damage to brain cells in a mouse model of Parkinson's disease.

20 Nov 2012

Janssen receives positive opinion from EMA CHMP for ZYTIGA to treat mCRPC

Janssen-Cilag International NV (Janssen) announced today that the Committee for Medical Products for Human Use (CHMP) of the European Medicines Agency (EMA) has granted a positive opinion recommending approval of the oral, once-daily medication ZYTIGA for use in combination with prednisone or prednisolone in the treatment of metastatic castration-resistant prostate cancer (mCRPC), in adult men who are asymptomatic or mildly symptomatic after failure of androgen deprivation therapy and in whom chemotherapy is not yet clinically indicated.

19 Nov 2012

New nanoparticle halts relapsing remitting multiple sclerosis in mouse model

In a breakthrough for nanotechnology and multiple sclerosis, a biodegradable nanoparticle turns out to be the perfect vehicle to stealthily deliver an antigen that tricks the immune system into stopping its attack on myelin and halt a model of relapsing remitting multiple sclerosis (MS) in mice, according to new Northwestern Medicine research.

19 Nov 2012

NIH-funded scientists develop new treatment to combat autoimmune disorders in mouse model

In a mouse model of multiple sclerosis (MS), researchers funded by the National Institutes of Health have developed innovative technology to selectively inhibit the part of the immune system responsible for attacking myelin-the insulating material that encases nerve fibers and facilitates electrical communication between brain cells.

18 Nov 2012

Tregs appears to play an important role in suppressing immune response in advance of sepsis

Following an infection, dysregulation of the immune system can result in a systemic inflammatory response and an often fatal condition called severe sepsis or septic shock. Sepsis is not uncommon, yet its cause and underlying immune dysfunction remain poorly understood.

17 Nov 2012

GW researcher gets NCI grant to study behavior of parasitic worm in bile duct cancer

Paul Brindley, Ph.D., professor of microbiology, immunology, and tropical medicine at the George Washington University School of Medicine and Health Sciences, was the recipient of a $1.7 million grant from the National Cancer Institute to study the behavior of a parasitic worm, rampant in Southeast Asia, known to cause infections that contribute to liver cancer.

16 Nov 2012

People with Prader-Willi Syndrome may have impaired autonomic nervous system

An Australian study reveals that people with the rare genetic disorder known as Prader-Willi Syndrome may have an impaired autonomic nervous system. This discovery opens up a new way of looking at the insatiable appetite experienced by all sufferers, as well as their very high risk of cardiovascular disease.

16 Nov 2012

Researchers discover unlikely recipe to kill antibiotic resistant bacteria

Washington State University researchers have found an unlikely recipe for antibiotic resistant bacteria: Mix cow dung and soil, and add urine infused with metabolized antibiotic. The urine will kill off normal E. coli in the dung-soil mixture. But antibiotic-resistant E. coli will survive in the soil to recolonize in a cow's gut through pasture, forage or bedding.

16 Nov 2012

Flu virus suppresses body's ability to defend against bacteria

When infected with influenza, the body becomes an easy target for bacteria. The flu virus alters the host's immune system and compromises its capacity to effectively fight off bacterial infections. Now, a team of immunologists at the Helmholtz Centre for Infection Research (HZI) and cooperation partners has discovered that an immune system molecule called TLR7 is partly to blame. The molecule recognizes the viral genome - and then signals scavenger cells of the immune system to ingest fewer bacteria.

15 Nov 2012

Smoking affects development of peripheral allergy-relevant stem cells in the blood

Environmental contaminants, such as smoking, are harmful to the human organism in relation to the occurrence of allergies. This is known. Until now, researchers had never investigated whether and to what extent environmental contaminants also affect allergy-relevant stem cells.

15 Nov 2012

Potential diagnostic method to identify subset of patients with chronic fatigue syndrome

For the first time, researchers have landed on a potential diagnostic method to identify at least a subset of patients with chronic fatigue syndrome (CFS), a complex disorder with no known definitive cause or cure.

15 Nov 2012

Review: Even very low radiation levels are harmful to life

Even the very lowest levels of radiation are harmful to life, scientists have concluded in the Cambridge Philosophical Society's journal Biological Reviews.

14 Nov 2012

Pathway between maternal obesity and childhood asthma nonallergic

Maternal pre-pregnancy bodyweight is associated with the risk for children developing asthma and wheezing by the age of 7 years, Danish research shows.

13 Nov 2012

Overcleanliness in childhood may increase risk for peanut allergy

An increased incidence of peanut allergy in children from more wealthy families supports the “hygiene hypothesis” that overcleanliness may promote the onset of childhood allergies, say US researchers.

9 Nov 2012

Malaria vaccine reduced severe and uncomplicated malaria by a third in young infants when given with other routine vaccines

Experts from the London School of Hygiene & Tropical Medicine today comment on the results of a malaria vaccine trial.

9 Nov 2012

Leading allergy organizations release report that sheds light on angioedema

With today's modern medicine, misdiagnoses may be unexpected and surprising. But when symptoms of an unknown and uncommon illness mimic a number of other conditions, it can be difficult for medical professionals to properly diagnose and treat patients. That's why four leading allergy/immunology organizations have announced the release of a report to help set a new standard for a commonly misdiagnosed, under-recognized and under treated condition known as angioedema, the rapid swelling of deep layers of skin and tissue.

9 Nov 2012

New intervention strategies needed to reach HIV-infected youth at birth

As youth infected at birth with HIV reach adolescence and young adulthood, a new study published in Clinical Infectious Diseases underscores the need to promote healthy behaviors as some of these young people become sexually active.

9 Nov 2012

Internet may foresee height of allergy suffering

While it's believed that Nostradamus' prophecies predicted many historical events, his digital successor, the Internet, may be foreseeing the height of allergy suffering. According to allergist Leonard Bielory, M.D., American College of Allergy, Asthma and Immunology (ACAAI) board member, Google search volume is shedding light on the most common allergy symptoms, when searches peak and how they pertain to pollen types.

9 Nov 2012

Lone star tick causes alpha-gal meat sensitivity in regional population

Meat lovers living in the central and southern regions of the country might be opting for a vegetarian lifestyle if meat comes with an unwanted side of a life-threatening allergic reaction. According to a study presented at the Annual Scientific Meeting of the American College of Allergy, Asthma and Immunology (ACAAI), the lone star tick inhabiting these regions is the primary reason for what's known as a meat induced alpha-gal allergic reaction.

9 Nov 2012

Genetic ancestry may exacerbate asthma among African American males

African American males are among those at greatest risk for severe asthma attacks. In a new study presented at the American College of Allergy, Asthma and Immunology's (ACAAI) Annual Scientific Meeting in Anaheim, Calif. Nov. 8-13, researchers assessed the relationship between genetic ancestry and severe asthma.

9 Nov 2012