Immunology News and Research

Latest Immunology News and Research

Janssen receives FDA approval for ZYTIGA to treat metastatic castration-resistant prostate cancer

Janssen announced today that the U.S. Food and Drug Administration (FDA) has approved a broader indication for the oral, once-daily medication ZYTIGA (abiraterone acetate).

10 Dec 2012

Targeting RAD52 protein can block the process by which leukemia stem cells repair themselves

Despite treatment with imatinib, a successful drug that targets chronic myeloid leukemia (CML), a deadly type of cancer, some patients may continue to be at risk for relapse because a tiny pool of stem cells is resistant to treatment and may even accumulate additional genetic aberrations, eventually leading to disease progression and relapse. These leukemia stem cells are full of genetic errors, loaded with potentially lethal breaks in DNA, and are in a state of constant self-repair.

10 Dec 2012

GSK, MD Anderson partner to develop new therapeutic antibodies against cancer

The University of Texas MD Anderson Cancer Center and GlaxoSmithKline (GSK) have signed a research collaboration and license agreement to develop new therapeutic antibodies that promote an immune system attack against cancer.

10 Dec 2012

C5aRA treatment could be effective against periodontitis

Periodontitis, a form of chronic gum disease that affects nearly half of the U.S. adult population, results when the bacterial community in the mouth becomes unbalanced, leading to inflammation and eventually bone loss. In its most severe form, which affects 8.5 percent of U.S. adults, periodontitis can impact systemic health.

9 Dec 2012

Pesticides in tap water may increase food allergy risk

Having a high level of urinary dichlorophenols is associated with the presence of food sensitization and allergies, say researchers.

7 Dec 2012

Scientists describe network map of genes involved in pain perception

Scientists in Australia and Austria have described a "network map" of genes involved in pain perception, with remarkable similarity from fruit flies to people. The work should help identify new analgesic drugs.

7 Dec 2012

Johns Hopkins focuses on MRSA, motherhood in November-December 2012 research news brief

Johns Hopkins Nursing researchers focus on MRSA, motherhood, hospital stress, intimate partner violence, and more in the November-December 2012 research news brief.

6 Dec 2012

Case Western Reserve to receive funding through Healthy Growth grant program

Case Western Reserve University School of Medicine announced that it will receive funding through the Achieving Healthy Growth program within the Grand Challenges in Global Health initiative.

6 Dec 2012

Moderna Therapeutics closes $40M in financing

Moderna Therapeutics announced today that it has closed more than $40 million in financing to date, led by Flagship Ventures and private investors, which will be used to advance multiple programs toward clinical stage development.

6 Dec 2012

Tenofovir DF safe and effective in treating adolescents with HBV

A recent clinical trial found that the adult antiviral drug, tenofovir disoproxil fumarate (tenofovir DF), is safe and effective in treating adolescents with hepatitis B virus (HBV). Trial results published in the December issue of Hepatology, a journal of the American Association for the Study of Liver Diseases (AASLD), show that tenofovir DF suppressed HBV in 89% of pediatric participants.

6 Dec 2012

Breast milk banks: an interview with Dr. Pieter Koorts

The available literature clearly demonstrates that in almost all circumstances a mother’s own breast milk is the ideal food for her infant. This is particularly important for preterm infants. Preterm infants are babies born before 37 completed weeks of pregnancy.

5 Dec 2012

Inserm prizes for medical research to be awarded on Dec. 3

The 2012 Inserm prizes for medical research will be awarded at a ceremony at the Coll-ge de France on Monday 3 December 2012. This year, the grand prize will be awarded to Philippe Sansonetti in the presence of Marisol Touraine, France's Minister of Social Affairs and Health, Genevi-ve Fioraso, France's Minister of Higher Education and Research, and Professor Andr- Syrota, Chairman and CEO of Inserm.

5 Dec 2012

Paper reveals how 'kinase' is distributed across membranes

Using a super-resolution fluorescent microscope, Australian medical scientists are a step closer to understanding why and how human immune cells decide to activate or not, thus enabling or preventing disease taking hold in the body.

5 Dec 2012

New study finds chemicals used for water purification can lead to food allergies

Food allergies are on the rise, affecting 15 million Americans. And according to a new study published in the December issue of Annals of Allergy, Asthma and Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI), pesticides and tap water could be partially to blame.

3 Dec 2012

Specific transporters could be exploited to deliver toxic substances into cancer cells

Whitehead Institute scientists report that certain molecules present in high concentrations on the surfaces of many cancer cells could be exploited to funnel lethal toxic molecules into the malignant cells. In such an approach, the overexpression of specific transporters could be exploited to deliver toxic substances into cancer cells.

3 Dec 2012

Loss of either T-bet or Eomes protein reduces immune system's ability to fight viral infection

When you get an acute infection, such as influenza, the body generally responds with a coordinated response of immune-cell proliferation and attack that rapidly clears the pathogen. Then, their mission done, the immune system stands down, leaving a population of sentinel memory cells to rapidly redeploy the immune system in the event of reinfection.

1 Dec 2012

Tissue damage, disease severity in C. diff. infection associated with disruption of PPARγ pathway

Researchers in the Nutritional Immunology and Molecular Medicine Laboratory at Virginia Bioinformatics Institute have discovered how a common diarrhea-causing bacterium sends the body's natural defenses into overdrive, actually intensifying illness while fighting infection.

1 Dec 2012

Study of hospital-acquired infection yields potential therapeutic target

30 Nov 2012

Four TSRI scientists named American Association for the Advancement of Science fellows

Four scientists from The Scripps Research Institute (TSRI) have been named fellows of the American Association for the Advancement of Science (AAAS). They are chemist Phil Baran, neuroscientist Hollis Cline, immunologist J. Lindsay Whitton, and chemist Jin-Quan Yu. Election as a AAAS fellow is an honor bestowed upon AAAS members by their peers

30 Nov 2012

Boehringer Ingelheim announces new data from volasertib Phase I/II leukemia study

Boehringer Ingelheim today announced that new data evaluating volasertib, an investigational polo-like kinase (Plk) inhibitor, will be presented at the 54th American Society of Hematology (ASH) annual meeting taking place December 8-11 in Atlanta, Ga.

30 Nov 2012

Immunology News and Research

Latest Immunology News and Research

Janssen receives FDA approval for ZYTIGA to treat metastatic castration-resistant prostate cancer

Targeting RAD52 protein can block the process by which leukemia stem cells repair themselves

GSK, MD Anderson partner to develop new therapeutic antibodies against cancer

C5aRA treatment could be effective against periodontitis

Pesticides in tap water may increase food allergy risk

Scientists describe network map of genes involved in pain perception

Johns Hopkins focuses on MRSA, motherhood in November-December 2012 research news brief

Case Western Reserve to receive funding through Healthy Growth grant program

Moderna Therapeutics closes $40M in financing

Tenofovir DF safe and effective in treating adolescents with HBV

Breast milk banks: an interview with Dr. Pieter Koorts

Inserm prizes for medical research to be awarded on Dec. 3

Paper reveals how 'kinase' is distributed across membranes

New study finds chemicals used for water purification can lead to food allergies

Specific transporters could be exploited to deliver toxic substances into cancer cells

Loss of either T-bet or Eomes protein reduces immune system's ability to fight viral infection

Tissue damage, disease severity in C. diff. infection associated with disruption of PPARγ pathway

Study of hospital-acquired infection yields potential therapeutic target

Four TSRI scientists named American Association for the Advancement of Science fellows

Boehringer Ingelheim announces new data from volasertib Phase I/II leukemia study

eBook: The Ultimate Guide to Successful Immunofluorescence eBook

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging