Immunology News and Research

Latest Immunology News and Research

Investigational treatment improves survival rate of babies lacking thymus

An investigational treatment pioneered by a Duke Health pediatrician resulted in a one-year survival rate of 77% among children born with a rare condition in which they lack an immune system.

4 Aug 2021

Study provides new insights for understanding dynamic changes in immune responses to COVID-19

A KAIST immunology research team found that a specific subtype of macrophages that originated from blood monocytes plays a key role in the hyper-inflammatory response in SARS-CoV-2 infected lungs, by performing single-cell RNA sequencing of bronchoalveolar lavage fluid cells.

4 Aug 2021

Lipid blast shield protects natural killer cells and also some cancer cells

A newly discovered fat 'shield' that prevents natural killer cells from being destroyed by their own deadly biological weapons also allows some cancer cells to evade an immune system attack, a study at Columbia University has found.

3 Aug 2021

Study sheds light on oral vaccine failure in mouse model of chronic gut disorder

A chronic gut disorder that occurs in regions with poor sanitation disrupts intestinal immune responses and impairs oral vaccine effectiveness in a mouse model of the disease, according to research led by UPMC Children's Hospital of Pittsburgh and University of Pittsburgh School of Medicine scientists.

3 Aug 2021

Public and private SARS-CoV-2 T cell receptors may be crucial for pan-coronavirus vaccines

Researchers have just established a structural basis for two spike glycoprotein epitopes of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that are restricted to human leukocyte antigen (HLA) A2 molecules. More specifically, they are involved in the presentation of antigenic peptides to specific T lymphocytes and recognized by public and private T cell receptors. The research is currently available on the bioRxiv* preprint server.

2 Aug 2021

Study provides new understanding on function of mitofusin 2 in cellular energy metabolism

Mitofusin 2 is a key protein in the regulation of the physiology of mitochondria ─cellular organelles that produce energy─ involved in several neurodegenerative and cardiovascular diseases, as well as in cancer.

30 Jul 2021

Antibacterial immunity may change in the intestines based on circadian cycle

The body's ability to prevent food poisoning by producing a natural antimicrobial compound increases during the day, when exposure to noxious bacteria is most likely, a new study by UT Southwestern scientists suggests.

28 Jul 2021

Biomarker shows potential to predict immunotherapy benefit for breast cancer patients

A biomarker that has proven to be a predictor for response to immunotherapies in melanoma patients also has clinical relevance for breast cancer patients, according to a new study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

27 Jul 2021

PerkinElmer to Acquire Antibody and Reagent Leader BioLegend

PerkinElmer, Inc. today announced it has entered into an agreement to acquire BioLegend, a leading, global provider of life science antibodies and reagents.

From Revvity 27 Jul 2021

Study could lead to blood-based diagnostic test for schizophrenia

Scientists at Sanford Burnham Prebys have discovered how levels of a protein could be used in the future as a blood-based diagnostic aid for schizophrenia.

27 Jul 2021

Study reveals safety of second mRNA COVID-19 vaccine dose after allergic reactions to first dose

In a multi-hospital analysis of individuals who experienced an allergic reaction to their first mRNA COVID-19 vaccine dose, all patients who went on to receive a second dose tolerated it without complications.

26 Jul 2021

Novel atlas charts how different antibodies attack a major piece of SARS-CoV-2 machinery

As the SARS-CoV-2 virus that causes COVID-19 continues to evolve, immunologists and infectious diseases experts are eager to know whether new variants are resistant to the human antibodies that recognized initial versions of the virus.

26 Jul 2021

Advantages and challenges of intranasal vaccines to fight against COVID-19 infections

There are many reasons that an intranasal vaccine against the SARS-CoV-2 virus would be helpful in the fight against COVID-19 infections, University of Alabama at Birmingham immunologists Fran Lund, Ph.D., and Troy Randall, Ph.D., write in a viewpoint article in the journal Science.

23 Jul 2021

Previously unknown brain repair process could be harnessed to treat seizures and epilepsy

University of Virginia School of Medicine researchers have discovered a previously unknown repair process in the brain that they hope could be harnessed and enhanced to treat seizure-related brain injuries.

23 Jul 2021

Clinical trials during a pandemic – lessons from COVID-19

In this interview, Dr. Benedicte Roquebert, Dr. Stephanie Haim-Boukobza and Dr. Souad Mehlal discuss how COVID-19 has resulted in new ways to think about clinical trials during a pandemic.

From Cerba Research 23 Jul 2021

Cell-analysis method could pave the way for new vaccine strategies against tuberculosis

A new method that analyzes how individual immune cells react to the bacteria that cause tuberculosis could pave the way for new vaccine strategies against this deadly disease, and provide insights into fighting other infectious diseases around the world.

22 Jul 2021

'Good cholesterol' protects the liver from inflammation and injury, study shows

The body's so-called good cholesterol may be even better than we realize. New research from Washington University School of Medicine in St. Louis suggests that one type of high-density lipoprotein (HDL) has a previously unknown role in protecting the liver from injury.

22 Jul 2021

SARS-CoV-2 reprograms host chromatic network to induce immune dysfunction

A recent study conducted at the University of Texas Science Center, Houston, in the USA, has revealed that upon infection, SARS-CoV-2 alters the host chromatin architecture to suppress antiviral interferon-responsive genes and augment inflammatory genes. The study is currently available on the bioRxiv* preprint server.

22 Jul 2021

Injecting mice with pulmonary endothelial cells can reverse symptoms of emphysema

Researchers at Weill Cornell Medicine and NewYork-Presbyterian in New York have discovered that injecting mice with pulmonary endothelial cells-the cells that line the walls of blood vessels in the lung-can reverse the symptoms of emphysema.

21 Jul 2021

Researchers identify immune protein linked to rare neurodegenerative disease

UT Southwestern researchers have identified an immune protein tied to the rare neurodegenerative condition known as Niemann-Pick disease type C.

21 Jul 2021

Immunology News and Research

Latest Immunology News and Research

Investigational treatment improves survival rate of babies lacking thymus

Study provides new insights for understanding dynamic changes in immune responses to COVID-19

Lipid blast shield protects natural killer cells and also some cancer cells

Study sheds light on oral vaccine failure in mouse model of chronic gut disorder

Public and private SARS-CoV-2 T cell receptors may be crucial for pan-coronavirus vaccines

Study provides new understanding on function of mitofusin 2 in cellular energy metabolism

Antibacterial immunity may change in the intestines based on circadian cycle

Biomarker shows potential to predict immunotherapy benefit for breast cancer patients

PerkinElmer to Acquire Antibody and Reagent Leader BioLegend

Study could lead to blood-based diagnostic test for schizophrenia

Study reveals safety of second mRNA COVID-19 vaccine dose after allergic reactions to first dose

Novel atlas charts how different antibodies attack a major piece of SARS-CoV-2 machinery

Advantages and challenges of intranasal vaccines to fight against COVID-19 infections

Previously unknown brain repair process could be harnessed to treat seizures and epilepsy

Clinical trials during a pandemic – lessons from COVID-19

Cell-analysis method could pave the way for new vaccine strategies against tuberculosis

'Good cholesterol' protects the liver from inflammation and injury, study shows

SARS-CoV-2 reprograms host chromatic network to induce immune dysfunction

Injecting mice with pulmonary endothelial cells can reverse symptoms of emphysema

Researchers identify immune protein linked to rare neurodegenerative disease

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