Immunology News and Research

Latest Immunology News and Research

Clinical trial to test personalized treatment for severe asthma caused by a specific mutation

Under a $10 million grant, a randomized, placebo-controlled clinical trial led by Boston Children's Hospital will test a personalized treatment for a form of severe asthma to which Black and Latinx children and adults are especially vulnerable.

21 Jul 2021

Older people appear to have diminished antibody response after COVID-19 vaccination

Older people appear to have fewer antibodies against the novel coronavirus, a new laboratory study from Oregon Health & Science University suggests.

21 Jul 2021

Researchers use information theory to monitor resistance mechanisms to targeted cancer therapy

One of the major challenges in modern cancer therapy is the adaptive response of cancer cells to targeted therapies: initially, these therapies are very often effective, then adaptive resistance occurs, allowing the tumor cells to proliferate again.

21 Jul 2021

Vitamin C and TET proteins can work together to give regulatory T cells their life-saving power

You can't make a banana split without bananas. And you can't generate stable regulatory T cells without Vitamin C or enzymes called TET proteins, it appears.

21 Jul 2021

Scientists explore susceptibility of different animals to SARS-CoV-2 infection

A team of researchers at the Institute of Infectious Diseases (IFIK) at the University of Bern and the Institute of Virology and Immunology (IVI) has utilized a unique collection of advanced cell culture models of cells lining the airways from various domesticated and wildlife animals. This way, the team can determine which animals are susceptible to SARS-CoV-2 infection.

20 Jul 2021

New substance derived from Saussurea controversa exhibits osteoprotective properties

Metabolic bone diseases, including osteoporosis, when bones lose their mass and become so fragile that they could be damaged while sneezing or under little stress, are called the silent epidemic of the 21st century.

20 Jul 2021

IgA deficiency results in substantial intestinal inflammation, study reveals

While researchers have known for years that immunoglobulin A (IgA) is important for gut health, it has remained unclear exactly what role it plays in preventing infection and disease. But now, researchers from Japan have found that eliminating IgA disrupts the balance of the intestinal ecosystem, making it susceptible to disease.

20 Jul 2021

Yeast expressed, RBD-based vaccine provides robust immune responses against SARS-CoV-2

The ongoing coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused over 190 million cases worldwide. Of these, over 4 million have died due to the infection.

20 Jul 2021

T cells can be engineered to fight tumors without succumbing to exhaustion

Fighting a tumor is a marathon, not a sprint. For cancer-fighting T cells, the race is sometimes just too long, and the T cells quit fighting. Researchers even have a name for this phenomenon: T cell exhaustion.

19 Jul 2021

New online tool launched to accelerate discoveries for reversing progressive hearing loss

Researchers at the University of Maryland School of Medicine launched a new online tool that could more quickly advance medical discoveries to reverse progressive hearing loss.

19 Jul 2021

Study: Second dose of COVID-19 vaccine induces a powerful boost to the immune system

The second dose of a COVID-19 vaccine induces a powerful boost to a part of the immune system that provides broad antiviral protection, according to a study led by investigators at the Stanford University School of Medicine.

19 Jul 2021

SARS-CoV-2 B.1.617 mutations L452 and E484Q do not work together to evade antibodies

A short report recently published in the Journal of Infectious Diseases demonstrates how spike mutations L452R and E484Q found in the variant B.1.617.1 of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) each confer modestly diminished sensitivity to Pfizer-BioNTech (BNT162b2) mRNA vaccine-elicited antibodies – with combined mutations having a similar impact as either one of them alone.

19 Jul 2021

Evaluation of a synthetic DNA SARS-CoV-2 vaccine INO-4800 using a nonhuman primate model

A new study published in Vaccine assesses the safety and efficacy of the synthetic DNA vaccine candidate INO-4800, delivered as a single or double dose regime.

18 Jul 2021

Researchers isolate human monoclonal antibodies that may neutralize several norovirus variants

Researchers at Vanderbilt University Medical Center and the Baylor College of Medicine in Houston, Texas, have taken a big step toward developing targeted treatments and vaccines against a family of viruses that attacks the gastrointestinal tract.

16 Jul 2021

UCSF researchers discover how the immune system may play a role in miscarriage

Researchers at UC San Francisco are zeroing in on how the immune system may play a role in miscarriage, which affects about a quarter of pregnancies.

16 Jul 2021

Researchers identify novel disorder resulting from a mutation in AIOLOS protein

Primary immunodeficiencies, such as severe combined immunodeficiency disease (SCID), occur when the immune system does not work properly, leading to increased susceptibility to various infections, autoimmunity, and cancers.

16 Jul 2021

Psychiatric patients have higher odds of hospitalization and death following COVID-19

In the largest systematic review and meta-analysis to date on COVID-19 outcomes in individuals with psychiatric disorders, the odds of dying or being hospitalized following COVID-19 infection were determined to be twice as high in comparison to persons without mental disorders.

16 Jul 2021

Immunology News and Research

Latest Immunology News and Research

Clinical trial to test personalized treatment for severe asthma caused by a specific mutation

Older people appear to have diminished antibody response after COVID-19 vaccination

Researchers use information theory to monitor resistance mechanisms to targeted cancer therapy

Vitamin C and TET proteins can work together to give regulatory T cells their life-saving power

Scientists explore susceptibility of different animals to SARS-CoV-2 infection

New substance derived from Saussurea controversa exhibits osteoprotective properties

IgA deficiency results in substantial intestinal inflammation, study reveals

Yeast expressed, RBD-based vaccine provides robust immune responses against SARS-CoV-2

T cells can be engineered to fight tumors without succumbing to exhaustion

New online tool launched to accelerate discoveries for reversing progressive hearing loss

Study: Second dose of COVID-19 vaccine induces a powerful boost to the immune system

SARS-CoV-2 B.1.617 mutations L452 and E484Q do not work together to evade antibodies

Evaluation of a synthetic DNA SARS-CoV-2 vaccine INO-4800 using a nonhuman primate model

Researchers isolate human monoclonal antibodies that may neutralize several norovirus variants

UCSF researchers discover how the immune system may play a role in miscarriage

Researchers identify novel disorder resulting from a mutation in AIOLOS protein

Psychiatric patients have higher odds of hospitalization and death following COVID-19

Researchers find a promising avenue for more effective treatment of antibiotic-resistant bacteria

Researchers study the role of subnuclear NSrp70 in T cell-mediated adaptive immunity

Short chain fatty acids have potential therapeutic applications against COVID-19, study suggests

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