Immunotherapy News and Research

Latest Immunotherapy News and Research

Efficacy of cancer immunotherapy increased by deactivating tumor defence mechanism

Novel bifunctional immunotherapeutic agents have been developed that, as well as deactivating key immune checkpoints,deactivate the tumor's protective response.

23 Feb 2018

Penn study sheds new light on immune cell identity

Almost all cells in the human body have identical DNA sequences, yet there are 200-plus cell types with different sizes, shapes, and chemical compositions. Determining what parts of the genome are read to make protein and which are silenced is orchestrated by proteins called transcription factors.

21 Feb 2018

Women with type 1 diabetes not protected against coronary artery disease

Constrictions of the coronary blood vessels is a possible consequence of type 1 diabetes, and one that can eventually lead to myocardial infarction or heart failure.

20 Feb 2018

Researchers find high risk of suicide among unaccompanied refugee minors

In a report written on behalf of the Swedish National Board of Health and Welfare, researchers at Karolinska Institutet have concluded that the risk of suicide among unaccompanied refugee minors and young adults in 2017 was nine times higher than the equivalent figure for the same age group in the Swedish population.

19 Feb 2018

Research finds rising trend in incidence of merkel cell carcinoma

Merkel cell carcinoma is a rare type of skin cancer, affecting only a few thousand people each year, compared to tens of thousands with melanoma. But while it may not be as common as other skin cancers, MCC is highly aggressive and often deadly -; and it's also becoming more common, according to new research published in the Journal of the American Academy of Dermatology and presented at the American Academy of Dermatology 2018 Annual Meeting in San Diego.

19 Feb 2018

New guidelines offer recommendations for assessment, management of immunotherapy side effects

Immunotherapy with immune checkpoint inhibitors is the first of a new generation of immunotherapy treatments, revolutionizing treatment for many different types of cancer. By unleashing the body's immune system to attack cancer, these treatments can send even the most hard-to-treat cancers into lasting remission.

15 Feb 2018

New NK cell-based immunotherapy effective against several types of leukemia

Researchers at Karolinska Institutet in Sweden have explored NK cell-based immunotherapy on patients with treatment-resistant leukemia. The study, which is published in the scientific journal Clinical Cancer Research, shows that the new therapy is effective against several types of leukemia.

15 Feb 2018

Oncolytic virus alerts the immune system to attack tumors

A new UC San Francisco study has shown that a cancer-killing virus currently in clinical trials may function as a cancer vaccine - in addition to killing some cancer cells directly, the virus alerts the immune system to the presence of a tumor, triggering a powerful, widespread immune response that kills cancer cells far outside the virus-infected region.

14 Feb 2018

Trial shows safety, feasibility of adding immunotherapy during chemoradiation for head and neck cancer

Analysis of a clinical trial, RTOG Foundation 3504, finds that nivolumab immunotherapy can be administered safely in conjunction with radiation therapy and chemotherapy for patients with newly diagnosed local-regionally advanced head and neck cancers.

13 Feb 2018

Study reports longer survival for obese men with metastatic melanoma

Obese patients with metastatic melanoma who are treated with targeted or immune therapies live significantly longer than those with a normal body mass index, investigators report in a study published in Lancet Oncology of 1,918 patients in six independent clinical cohorts.

13 Feb 2018

Professor Jean-Charles Soria granted award for pioneering role in cancer drug development

The TAT 2018 Honorary Award for cancer drug development has been granted to Professor Jean-Charles Soria, for his pioneering role in cancer drug development across molecular targeted agents, precision medicine, and immunotherapy.

12 Feb 2018

Lesser-known CRS-HIPEC treatment for cancers that have spread to abdominal cavity

While cancer treatment advances are being made in the areas of precision medicine and immunotherapy, a unique combination of traditional therapies can also provide some cancer patients a treatment option that may provide significant benefit.

11 Feb 2018

Molecular 'magnets' could help develop better immunotherapies for cancer patients

Chemicals that attract specialized immune cells toward tumors could be used to develop better immunotherapies for cancer patients, according to new research published in Cell.

9 Feb 2018

Researchers develop novel antibody-based therapy to treat organ fibrosis

Fibrosis can be triggered by many events- surgery, injury, disease- but regardless of the cause, it's characterized by accumulating masses of collagen-packed scar tissue that can permanently damage compromised organs.

6 Feb 2018

Moffitt study identifies new drug target that may reduce GVHD risk

Stem cell transplants can cure patients with high-risk leukemia or lymphoma. Graft-versus-host disease is a potentially life-threatening side effect that occurs when the donor's immune cells attack the recipient's normal tissues.

5 Feb 2018

Scientists develop immune-stimulating injections against cancer

A team of researchers have developed two immune-stimulating injections, that removed all traces of cancer when injected directly into solid mouse tumors.

2 Feb 2018

Two bacterial species collaborate to drive development of colon cancers

Patients with an inherited form of colon cancer harbor two bacterial species that collaborate to encourage development of the disease, and the same species have been found in people who develop a sporadic form of colon cancer, a study led by a Johns Hopkins Bloomberg~Kimmel Institute for Cancer Immunotherapy research team finds.

1 Feb 2018

Historic study involving Simmons Cancer Center shows effectiveness of CAR-T therapy

A historic study involving researchers from UT Southwestern's Harold C. Simmons Comprehensive Cancer Center demonstrates the effectiveness of CAR-T therapy, which uses genetically modified immune cells to treat acute lymphoblastic leukemia (ALL) in children and young adults. The research appears in the New England Journal of Medicine.

1 Feb 2018

NCCN sets new record for guidelines and events

More than eight million copies of the NCCN Clinical Practice Guidelines in Oncology were downloaded in 2017, marking a 16% increase over 2016, and setting a new personal record for the National Comprehensive Cancer Network.

31 Jan 2018

Study lays groundwork for using PD-1 inhibitors against aggressive form of pediatric brain cancer

One type of immunotherapy removes a genetic blindfold that cancer uses to hide from the immune system. These "PD-1 inhibitors", including drugs like pembrolizumab, nivolumab and atezolizumab, have proven useful and have even in some cases revolutionized the treatment of common adult cancers ranging from melanoma, to lung cancer, to kidney cancer and more.

30 Jan 2018

Immunotherapy News and Research

Latest Immunotherapy News and Research

Efficacy of cancer immunotherapy increased by deactivating tumor defence mechanism

Penn study sheds new light on immune cell identity

Women with type 1 diabetes not protected against coronary artery disease

Researchers find high risk of suicide among unaccompanied refugee minors

Research finds rising trend in incidence of merkel cell carcinoma

New guidelines offer recommendations for assessment, management of immunotherapy side effects

New NK cell-based immunotherapy effective against several types of leukemia

Oncolytic virus alerts the immune system to attack tumors

Trial shows safety, feasibility of adding immunotherapy during chemoradiation for head and neck cancer

Study reports longer survival for obese men with metastatic melanoma

Professor Jean-Charles Soria granted award for pioneering role in cancer drug development

Lesser-known CRS-HIPEC treatment for cancers that have spread to abdominal cavity

Molecular 'magnets' could help develop better immunotherapies for cancer patients

Researchers develop novel antibody-based therapy to treat organ fibrosis

Moffitt study identifies new drug target that may reduce GVHD risk

Scientists develop immune-stimulating injections against cancer

Two bacterial species collaborate to drive development of colon cancers

Historic study involving Simmons Cancer Center shows effectiveness of CAR-T therapy

NCCN sets new record for guidelines and events

Study lays groundwork for using PD-1 inhibitors against aggressive form of pediatric brain cancer

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Immunotherapy News and Research

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