Immunotherapy News and Research

Latest Immunotherapy News and Research

Researchers discover genetic mechanism for resistance to immunotherapy drugs

An urgent question for cancer scientists is why immunotherapy achieves dramatic results in some cases but doesn't help most patients.

5 Jan 2018

New yardstick offers practical recommendations for treatment of atopic dermatitis

Patients with atopic dermatitis (AD) - also known as eczema - often face a tough, uphill battle for treatment. Symptoms include severe itching, scaly rashes, extreme dry skin and inflammation.

4 Jan 2018

Researchers discover novel genes responsible for Alzheimer's disease

Researchers have identified several new genes responsible for Alzheimer's disease (AD) including those leading to functional and structural changes in the brain and elevated levels of AD proteins in cerebrospinal fluid (CSF).

3 Jan 2018

Rutgers researcher receives $1 million grant for international prostate cancer study

A $1 million grant from Gateway for Cancer Research will help Rutgers Cancer Institute of New Jersey Urologic Oncology Chief Isaac Yi Kim, MD, PhD, MBA evaluate the impact of surgically removing the prostate in men with metastatic prostate cancer in the United States and Asia.

2 Jan 2018

Gene therapy with CAR T-cells could create long-term immunity from HIV

Through gene therapy, researchers engineered blood-forming stem cells (hematopoietic stem/progenitor cells, or HSPCs) to carry chimeric antigen receptor (CAR) genes to make cells that can detect and destroy HIV-infected cells.

29 Dec 2017

Nanobiotix receives FDA approval for first immuno-oncology trial

NANOBIOTIX, a late clinical-stage nanomedicine company pioneering new approaches to the treatment of cancer, today announced the U.S. Food and Drug Administration has approved its Investigational New Drug Application for NBTXR3, a first-in-class nanoparticle designed for direct injection into cancerous tumors, activated by stereotactic ablative radiotherapy (SABR) and administered in combination with an anti-PD1 antibody (nivolumab or pembrolizumab).

26 Dec 2017

Higher ‘mutational burden’ of tumors predicts success rate with cancer immunotherapies

The "mutational burden," or the number of mutations present in a tumor's DNA, is a good predictor of whether that cancer type will respond to a class of cancer immunotherapy drugs known as checkpoint inhibitors, a new study led by Johns Hopkins Kimmel Cancer Center researchers shows.

21 Dec 2017

Study findings could lead to less expensive and more effective cancer treatments

The latest generation of cancer treatments spring from the discovery that the human immune system is able to beat the disease. Like Dorothy in "The Wizard of Oz," what research teams around the world have spent decades searching for was right in their own backyard all along.

20 Dec 2017

New recommendations aim to improve diagnosis of liver disease, prevent unnecessary tests

New recommendations, led by experts at the University of Birmingham, have been published to improve the use of liver blood tests.

20 Dec 2017

Special precautions not required when people with egg allergy take flu shots

For years, people with an egg allergy have been told to avoid or take special precautions when getting a flu shot because most influenza vaccines are grown in eggs and contain a tiny amount of egg protein. An updated practice parameter from the Joint Task Force on Practice Parameters stresses that people with egg allergy should receive their yearly flu shot, and that no special precautions are required.

19 Dec 2017

Mountain cedar allergy season set to strike this year

Allergy specialists like Dr. Shelly Harvey are again readying themselves for mountain cedar, the annual irritant that makes noses run and eyes itch – potentially transforming the merriest of holiday well-wishers into miserable Ebenezer Scrooges.

19 Dec 2017

Treatment for skin cancer could be more effective if combined with arthritis drug

Treatment for the most deadly form of skin cancer could be more effective if combined with a well-known drug for rheumatoid arthritis, new research has shown.

19 Dec 2017

Research uncovers mechanism implicated in defective function of tumor-associated dendritic cells

A new study from The Wistar Institute revealed the mechanism implicated in the defective function of tumor-associated dendritic cells (DCs), a specialized type of immune cells that expose the antigens on their surface to activate the T cells.

15 Dec 2017

Cancer immunotherapy’s effectiveness may depend on patient’s genetic makeup

Cancer cells arise when DNA is mutated, and these cells should be recognized as "foreign" by the immune system. However, cancer cells have found ways to evade detection by the immune system.

15 Dec 2017

People diagnosed with schizophrenia or bipolar disorder may actually have treatable condition

Researchers at Houston Methodist believe that a significant number of people diagnosed with schizophrenia or bipolar disorder may actually have a treatable immune system condition.

14 Dec 2017

Researchers discover potential regulator essential for killer T cells to reside in tumors

Researchers report the discovery that a protein called "Runx3" programs killer T cells to establish residence in tumors and infection sites.

11 Dec 2017

Pairing immunotherapy drug with chemotherapy proves beneficial for relapsed acute myeloid leukemia

University of North Carolina Lineberger Comprehensive Cancer Center researchers report that pairing an immunotherapy drug with chemotherapy proved beneficial for some patients with acute myeloid leukemia whose disease did not respond to standard treatment or had relapsed.

11 Dec 2017

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

In a pair of clinical trials stretching from Philadelphia to Tokyo, the chimeric antigen receptor (CAR) T cell therapy Kymriah (formerly known as CTL019) demonstrated long-lasting remissions in non-Hodgkin's lymphoma (NHL) patients.

11 Dec 2017

Drug improves disease-free, overall survival after hematopoietic stem cell transplants

Results from a phase 2 clinical trial, presented by Seattle Children's Research Institute at the 59th American Society of Hematology Annual Meeting, show that the drug Abatacept (Orencia) nearly eliminated life-threatening severe acute graft-versus-host disease (GvHD) in patients receiving hematopoietic stem cell transplants.

11 Dec 2017

Two immunotherapy approaches for multiple myeloma show hope

Researchers from the University of Pennsylvania's Abramson Cancer Center have developed two experimental immunotherapy methods that include one chimeric antigen receptor (CAR) T cell therapy for the treatment of multiple myeloma patients who were not responding to other treatments.

11 Dec 2017

Immunotherapy News and Research

Latest Immunotherapy News and Research

Researchers discover genetic mechanism for resistance to immunotherapy drugs

New yardstick offers practical recommendations for treatment of atopic dermatitis

Researchers discover novel genes responsible for Alzheimer's disease

Rutgers researcher receives $1 million grant for international prostate cancer study

Gene therapy with CAR T-cells could create long-term immunity from HIV

Nanobiotix receives FDA approval for first immuno-oncology trial

Higher ‘mutational burden’ of tumors predicts success rate with cancer immunotherapies

Study findings could lead to less expensive and more effective cancer treatments

New recommendations aim to improve diagnosis of liver disease, prevent unnecessary tests

Special precautions not required when people with egg allergy take flu shots

Mountain cedar allergy season set to strike this year

Treatment for skin cancer could be more effective if combined with arthritis drug

Research uncovers mechanism implicated in defective function of tumor-associated dendritic cells

Cancer immunotherapy’s effectiveness may depend on patient’s genetic makeup

People diagnosed with schizophrenia or bipolar disorder may actually have treatable condition

Researchers discover potential regulator essential for killer T cells to reside in tumors

Pairing immunotherapy drug with chemotherapy proves beneficial for relapsed acute myeloid leukemia

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

Drug improves disease-free, overall survival after hematopoietic stem cell transplants

Two immunotherapy approaches for multiple myeloma show hope

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Immunotherapy News and Research

Latest Immunotherapy News and Research

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Utilizing process Raman in optimizing cultivated meat production

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