Immunotherapy News and Research

Latest Immunotherapy News and Research

Research findings pave way to better tailored treatment for oesophageal cancer

Scientists have discovered that oesophageal cancer can be classified into three different subtypes, paving the way for testing targeted treatments tailored to patients' disease for the first time.

6 Sep 2016

Scientists combine immunotherapy with chemotherapy to eliminate cancer recurrence

Scientists from the United States have made an important step toward eliminating cancer recurrence by combining immunotherapy with chemotherapy.

1 Sep 2016

Experimental drug may become key tool to target triple-negative breast cancer with immunotherapy

Previous studies at the University of Colorado Cancer Center show that the experimental drug AMPI-109 potently kills triple-negative breast cancer cells.

30 Aug 2016

New NCCN Imaging AUC released for eight new cancers

The National Comprehensive Cancer Network, a Centers for Medicare & Medicaid Services-approved provider-led entity for imaging appropriate use criteria, continues to build its library of AUC and has published NCCN Imaging Appropriate Use Criteria for eight new cancer types. Launched in June 2016, NCCN Imaging AUC currently are available for 20 cancer types.

29 Aug 2016

Janssen seeks to extend DARZALEX license to benefit more multiple myeloma patients

Janssen-Cilag International NV has announced the submission of a Type II variation application to the European Medicines Agency (EMA), seeking to broaden the existing marketing authorisation for the immunotherapy DARZALEX® (daratumumab) to include treatment of adult patients with relapsed multiple myeloma who have received at least one prior therapy. The expanded indication is based on daratumumab in combination with lenalidomide (an immmunomodulatory agent) and dexamethasone, or bortezomib (a PI) and dexamethasone.

29 Aug 2016

Curbing immune system infighting could make treatment more effective for pancreatic cancer

Internal conflict between cell types explains why the immune system struggles to recognize and attack pancreatic cancer.

25 Aug 2016

Three like-minded nonprofits collaborate to launch immunotherapy clinical trial for pediatric brain tumors

A Kids' Brain Tumor Cure Foundation, Solving Kids' Cancer and the Ty Louis Campbell Foundation announce their joint financial support of a Phase 1 clinical trial to test the safety and efficacy of combination checkpoint inhibitors in the treatment of children with brain tumors.

25 Aug 2016

NIBIB researchers develop nanovaccine to enhance cancer immunotherapy

NIBIB researchers have created a nanovaccine that could make a current approach to cancer immunotherapy more effective while also reducing side effects.

25 Aug 2016

Stem cells derived from bone marrow provide better quality of life to transplant patients

A large, nationwide study published in the journal JAMA Oncology found that people who received transplants of cells collected from a donor's bone marrow the original source for blood stem cell transplants, developed decades ago had better self-reported psychological well-being, experienced fewer symptoms of a common post-transplant side effect called graft-vs.-host disease and were more likely to be back at work five years after transplantation than those whose transplanted cells were taken from the donor's bloodstream.

17 Aug 2016

FDA grants Orphan Drug Designation to CD4CAR therapy for treatment of peripheral T-cell lymphoma

iCell Gene Therapeutics today (Aug. 11) announced that the Food and Drug Administration has granted Orphan Drug Designation for its chimeric antigen receptor engineered T-cells directed against the target protein CD4 (CD4CAR) for the treatment of peripheral T-cell lymphoma (PTCL).

12 Aug 2016

Analysis of biopsies during early treatment predicts patient’s response to melanoma immunotherapy

Immune response measured in tumor biopsies during the course of early treatment predicts which melanoma patients will benefit from specific immune checkpoint blockade drugs, researchers at The University of Texas MD Anderson Cancer Center report in the journal Cancer Discovery.

11 Aug 2016

Study finds oral immunotherapy safe, effective at suppressing peanut allergy in preschool children

Nearly 80 percent of peanut-allergic preschool children successfully incorporated peanut-containing foods into their diets after receiving peanut oral immunotherapy (OIT), a clinical trial has found.

10 Aug 2016

Researchers develop computational algorithm to analyze big genomic data for different cancers

University of Hawai'i Cancer Center researchers developed a computational algorithm to analyze "Big Data" obtained from tumor samples to better understand and treat cancer.

10 Aug 2016

CTCA at Western begins clinical trial for novel antibody to treat patients with advanced tumors

Cancer Treatment Centers of America at Western Regional Medical Center has dosed its first three patients as part of the launch of a Phase I clinical trial using a novel antibody to treat patients with advanced solid tumors.

8 Aug 2016

Immunotherapy innovations in oncology: an interview with Robert LaCaze

The body’s immune system is an excellent weapon against many diseases. For more than 100 years, immunology and immunotherapy have played an ever-increasing role in the understanding and treatment of cancer.

8 Aug 2016

Oncolytic virotherapy medicine shows positive treatment outcomes in late-stage cancer patients

The surprisingly positive treatment outcomes using Rigvir virotherapy for late stages cancer patients were recently published.

8 Aug 2016

Wistar scientists discover marker for PMN-MDSCs in the blood of cancer patients

Myeloid-derived suppressor cells (MDSCs) are a population of immune cells that have been implicated in tumor resistance to various types of cancer treatment, including targeted therapies, chemotherapy and immunotherapy.

5 Aug 2016

Experimental immunotherapeutic strategy may pave way for new treatments against lymphoma

Lymphoma is a cancer that affects lymphocytes, a type of white blood cell. The disease originates in a lymphoid organ (lymph node, spleen, or bone marrow) before spreading through the blood to infiltrate not only other lymphoid organs but also other tissues.

4 Aug 2016

Watch-and-wait approach may prove successful in subset of adults with advanced kidney cancer

Watch-and-wait approach means some patients could delay taking highly toxic non-curative anticancer drugs that come with substantial side effects

4 Aug 2016

PD-1-responsive T cells may offer clues to design more effective drugs for cancer

Cancer immunotherapy drugs that block the inhibitory PD-1 pathway have shown success in clinical trials and are now FDA-approved for melanoma, lung cancer and bladder cancer. Yet many patients' tumors do not respond to these drugs.

3 Aug 2016

Immunotherapy News and Research

Latest Immunotherapy News and Research

Research findings pave way to better tailored treatment for oesophageal cancer

Scientists combine immunotherapy with chemotherapy to eliminate cancer recurrence

Experimental drug may become key tool to target triple-negative breast cancer with immunotherapy

New NCCN Imaging AUC released for eight new cancers

Janssen seeks to extend DARZALEX license to benefit more multiple myeloma patients

Curbing immune system infighting could make treatment more effective for pancreatic cancer

Three like-minded nonprofits collaborate to launch immunotherapy clinical trial for pediatric brain tumors

NIBIB researchers develop nanovaccine to enhance cancer immunotherapy

Stem cells derived from bone marrow provide better quality of life to transplant patients

FDA grants Orphan Drug Designation to CD4CAR therapy for treatment of peripheral T-cell lymphoma

Analysis of biopsies during early treatment predicts patient’s response to melanoma immunotherapy

Study finds oral immunotherapy safe, effective at suppressing peanut allergy in preschool children

Researchers develop computational algorithm to analyze big genomic data for different cancers

CTCA at Western begins clinical trial for novel antibody to treat patients with advanced tumors

Immunotherapy innovations in oncology: an interview with Robert LaCaze

Oncolytic virotherapy medicine shows positive treatment outcomes in late-stage cancer patients

Wistar scientists discover marker for PMN-MDSCs in the blood of cancer patients

Experimental immunotherapeutic strategy may pave way for new treatments against lymphoma

Watch-and-wait approach may prove successful in subset of adults with advanced kidney cancer

PD-1-responsive T cells may offer clues to design more effective drugs for cancer

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Immunotherapy News and Research

Latest Immunotherapy News and Research

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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