Immunotherapy News and Research

Latest Immunotherapy News and Research

New treatment strategy makes pancreatic tumors sensitive to immunotherapy, mice study shows

Pancreatic cancer is one of the most aggressive and deadly tumor types and notorious for its resistance to virtually all types of treatment, including newer immunotherapies.

7 Mar 2022

Specific variant of the HLA-DPB1 gene linked with poor response to allergen immunotherapy

Although sublingual immunotherapy (SLIT) has become an effective treatment option for many allergies, about 20-30% of patients don’t respond to SLIT for Japanese cedar pollinosis–a highly common disease.

7 Mar 2022

T-cell cytokine and fatty acid work together to trigger a type of cell death

Researchers at the University of Michigan Rogel Cancer Center found that a cytokine, a category of protein that acts as messengers in the body, and a fatty acid can work together to trigger a type of cell death previously defined by studies with synthetic molecules.

4 Mar 2022

Melanoma patients do better on immunotherapy than completion lymph node dissection

For years, surgery for patients with stage III melanoma -; melanoma that has spread to the lymph nodes -; involved removing those lymph nodes along with the primary tumor.

4 Mar 2022

Microneedle treatments could significantly desensitize people with food allergies

Treating peanut allergy with microneedles could significantly improve desensitization by directly targeting the allergen to the skin, providing greater protection from severe allergic reactions for millions of people, a new study suggests.

4 Mar 2022

Novel approach to generate reliable breast tumor models may pave way for better immunotherapies

The discrepancy between preclinical advances in breast cancer immunotherapy and poor patient outcomes is rooted in the limitations of current breast cancer models. These models often fail to mimic complex interactions between cancer cells and key immune cells present in the tumor microenvironment.

3 Mar 2022

Study explores signature gut microbiome connection with immune checkpoint inhibitor response in advanced melanomas

Researchers from different countries performed a meta-analysis of real-world cross-cohorts and provided an association of the gut microbiome with immune checkpoint inhibitors response in patients with advanced melanomas.

2 Mar 2022

AI and machine learning could improve cancer diagnosis through biomarker discovery

Artificial intelligence (AI), deep learning (DL), and machine learning (ML) have transformed many industries and areas of science.

1 Mar 2022

Adding immunotherapy drug to standard head and neck cancer treatment increases patient survival

A University of Cincinnati clinical trial that added an immunotherapy drug to standard of care treatment regimens has shown increased survival rates for head and neck cancer patients with intermediate risk features.

1 Mar 2022

Microorganisms hindering cancer therapy have more influence than the beneficial ones, study says

Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on the types of microbes in their gut, and new research suggests the microorganisms hindering therapy have more influence than the beneficial ones.

28 Feb 2022

Understanding the gut microbiome could help personalize immunotherapy for melanoma

The largest study to date has confirmed the link between the gut microbiome and the response to cancer immunotherapy therapy for melanoma.

28 Feb 2022

Researchers develop new precision medicine technology for cancer immunotherapy

In recent years, great advances have been made in the development of new successful immunotherapies to treat cancer. CAR T-cell therapy and antibody treatments are two types of targeted immunotherapies that have revolutionized areas of cancer care.

28 Feb 2022

ESMO announces a new series of resources to guide physicians in oncological practice

ESMO, the leading professional organization for medical oncology, announces a new series of resources designed to guide physicians in areas of oncological practice not covered by guidelines, where current evidence is insufficient to evenly inform clinical decision-making.

28 Feb 2022

Triple antibody cocktail is a promising candidate for immunotherapy against SARS-CoV-2 variants of concern

Researchers generated a panel of bnAbs against SARS-CoV, SARS-CoV-2, and its variant VOCs, including Omicron from sequentially immunized mice.

28 Feb 2022

Clinical trial shows encouraging results with fecal microbiota transplants for peanut-allergic patients

Peanut allergies are hard to treat and can cause fatal or near-fatal anaphylactic reactions. People usually don't outgrow peanut allergy, requiring lifelong scrutiny of food labels to avoid even small traces of peanut.

27 Feb 2022

Unexpected discovery could open the door to new treatment for small-cell lung cancer

An unexpected discovery at UVA Cancer Center has allowed scientists to halt the development of small-cell lung cancer in lab mice, and the surprise finding could open the door to a new treatment approach in people.

25 Feb 2022

LJI researchers discover new genes in CD4+ "helper" T cell subsets

T cells play important roles in helping to fight infections and cancers-;and they can also drive autoimmune diseases. Now researchers at La Jolla Institute for Immunology (LJI) have discovered new genes in CD4+ "helper" T cell subset that are linked to risk of autoimmune diseases.

25 Feb 2022

Treatment with Tumor Treating Fields triggers downstream anti-tumor cell response, study finds

Novocure announced that a new study published in the Journal of Clinical Investigation (JCI) finds treatment with Tumor Treating Fields (TTFields) mediated cell disruption activates the immune system and triggers an anti-tumor cell response that may be effectively used together with existing immunotherapy approaches in the treatment of solid tumors, with limited systemic toxicity.

25 Feb 2022

Outcomes of SARS-Cov-2 infection in patients undergoing active anti-cancer treatment

Researchers demonstrated that irrespective of the type of ACT, SARS-CoV-2 infection rates in patients receiving ACT remained comparable to the general population.

25 Feb 2022

T cell responses in inflammatory bowel disease patients on immune-modifying agents after mRNA COVID-19 vaccination

Researchers characterized humoral and SARS-CoV-2 S-specific T cell responses in IBD patients who received two-dose mRNA-based COVID-19 vaccination series.

25 Feb 2022

Immunotherapy News and Research

Latest Immunotherapy News and Research

New treatment strategy makes pancreatic tumors sensitive to immunotherapy, mice study shows

Specific variant of the HLA-DPB1 gene linked with poor response to allergen immunotherapy

T-cell cytokine and fatty acid work together to trigger a type of cell death

Melanoma patients do better on immunotherapy than completion lymph node dissection

Microneedle treatments could significantly desensitize people with food allergies

Novel approach to generate reliable breast tumor models may pave way for better immunotherapies

Study explores signature gut microbiome connection with immune checkpoint inhibitor response in advanced melanomas

AI and machine learning could improve cancer diagnosis through biomarker discovery

Adding immunotherapy drug to standard head and neck cancer treatment increases patient survival

Microorganisms hindering cancer therapy have more influence than the beneficial ones, study says

Understanding the gut microbiome could help personalize immunotherapy for melanoma

Researchers develop new precision medicine technology for cancer immunotherapy

ESMO announces a new series of resources to guide physicians in oncological practice

Triple antibody cocktail is a promising candidate for immunotherapy against SARS-CoV-2 variants of concern

Clinical trial shows encouraging results with fecal microbiota transplants for peanut-allergic patients

Unexpected discovery could open the door to new treatment for small-cell lung cancer

LJI researchers discover new genes in CD4+ "helper" T cell subsets

Treatment with Tumor Treating Fields triggers downstream anti-tumor cell response, study finds

Outcomes of SARS-Cov-2 infection in patients undergoing active anti-cancer treatment

T cell responses in inflammatory bowel disease patients on immune-modifying agents after mRNA COVID-19 vaccination

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Immunotherapy News and Research

Latest Immunotherapy News and Research

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