Immunotherapy News and Research

Latest Immunotherapy News and Research

Researchers develop nanoparticles delivering STING agonists for intravenous cancer immunotherapy

Cancer immunotherapy seeks to turn "cold" tumors into "hot" tumors––those that respond to immunotherapy––by awakening and enlisting the body's own immune system.

30 Sep 2021

Additional supportive care services benefit older adults receiving chemotherapy, study finds

A clinical trial led by researchers at City of Hope, a world-renowned cancer research and treatment organization, showed that patients over 65 receiving chemotherapy experienced significantly fewer treatment-related side effects when a multidisciplinary team of experts analyzed each case and introduced personalized interventions.

30 Sep 2021

Study reveals how to improve overall immune response against virally driven cancers

Blocking the PD-1 inhibitory pathway within a subset of specialized T-cells may improve overall immune response against virally driven cancers, according to findings published in Nature.

30 Sep 2021

Long-held theory of cancer-induced immune suppression requires revision, study says

Many cancers produce an enzyme called IDO that suppresses immune system activity, but the long-held hypothesis of how this mechanism operates requires revision, according to a study published in Clinical Cancer Research.

29 Sep 2021

Researchers compare transcriptomic and cytokine responses of colorectal cancer cells

Oncotarget published "Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells" which reported that there was an increase in IL-8 by oxaliplatin and increase in ferritin by cisplatin which may contribute to cancer cell survival.

29 Sep 2021

Research provides the basis for an additional novel immunotherapy for multiple myeloma patients

Oncotarget published "Multipeptide stimulated PBMCs generate TEM/TCM for adoptive cell therapy in multiple myeloma" which reported that Multiple Myeloma patients suffer disease relapse due to the development of therapeutic resistance. Increasing evidence suggests that immunotherapeutic strategies can provide durable responses.

29 Sep 2021

Study reports on ex vivo drug delivery system for delivering MSCs to kidney disease patients

Scientists are reporting promising results in the early stages of a clinical trial designed to gauge the feasibility of a new type of treatment for people with acute kidney disease.

28 Sep 2021

Classic antidepressants show potential to enhance modern cancer treatments

Classic antidepressants could help improve modern cancer treatments. They slowed the growth of pancreatic and colon cancers in mice, and when combined with immunotherapy, they even stopped the cancer growth long-term.

28 Sep 2021

B cell activating anti-CD73 antibody for the immunotherapy of COVID-19

Despite the advent of numerous vaccines and the discovery of passive monoclonal antibodies for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), there remains an urgent need for definitive therapies for coronavirus disease-2019 (COVID-19) patients.

27 Sep 2021

Novel antibody candidate shows potent binding to diverse SARS-CoV-2 variant mutations

Twist Bioscience Corporation (Nasdaq: TWST) today reported that its internally-discovered antibody candidate TB202-3 (CoVIC-094), demonstrated potent binding to diverse SARS-CoV-2 variant mutations, including strains with the E484K, N501Y, D614G, Y453F and K417N mutations in pseudovirus assays, indicating this therapeutic antibody may be effective in treating many strains of COVID-19.

25 Sep 2021

NCI recognizes UC Davis as one of the most elite cancer centers

The National Cancer Institute once again recognized UC Davis Comprehensive Cancer Center as one of the nation's most elite cancer centers, awarding the center $17.5 million over five years and renewing the cancer center's "comprehensive" designation.

24 Sep 2021

Promising data from early clinical trials of new anticancer therapies presented at ESMO Congress 2021

Data from early clinical trials presented at the ESMO Congress 2021 suggest that new anticancer treatments are on the horizon, with a clear emphasis on precision medicine.

24 Sep 2021

AI technique could lead to new ways to predict cancer prognosis and treatment response

Researchers and data scientists at UT Southwestern Medical Center and MD Anderson Cancer Center have developed an artificial intelligence technique that can identify which cell surface peptides produced by cancer cells called neoantigens are recognized by the immune system.

24 Sep 2021

Melanomas that metastasize to the adrenal gland are resistant to checkpoint inhibitors

Recent advances in immunotherapy have allowed doctors at the University of Colorado Cancer Center to more effectively treat melanomas that spread to other parts of the body. Immunotherapy drugs such as checkpoint inhibitors, which are commonly used to treat melanomas, work to strengthen a patient's immune system so that it can prevent a tumor from "turning off" the ability of the immune system to fight it.

24 Sep 2021

Design of mRNA vaccines to combat COVID-19

A recent review study discusses fundamental concepts in the successful delivery of nucleic acids in therapeutics.

23 Sep 2021

Penn Medicine and Wistar secure $11.7 million SPORE grant for three melanoma research projects

Penn Medicine and The Wistar Institute have been awarded a prestigious $11.7 million Specialized Programs of Research Excellence, or SPORE, grant from the National Cancer Institute.

22 Sep 2021

Study findings could lead to novel ways to overcome tumor resistance to immunotherapies

Cancer-fighting immune cells in patients with lung cancer whose tumors do not respond to immunotherapies appear to be running on a different "program" that makes them less effective than immune cells in patients whose cancers respond to these immune treatments, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy.

22 Sep 2021

Oxford COVID vaccine technology has the potential to revolutionize cancer treatment

Scientists from the University of Oxford and the Ludwig Institute for Cancer Research are building on the success of the Oxford-AstraZeneca vaccine against SARS-CoV-2 to develop a vaccine to treat cancer.

21 Sep 2021

Researchers reveal a mechanism of SHP2-mediated tumor immunosuppression

Colorectal cancer (CRC), a malignant tumor worldwide consists of microsatellite instability (MSI) and stable (MSS) phenotypes. Although SHP2 is a hopeful target for cancer therapy, its relationship with innate immunosuppression remains elusive. To address that, the authors of this article performed single-cell RNA sequencing to explore the role of SHP2 in all cell types of tumor microenvironment (TME) from murine MC38 xenografts.

21 Sep 2021

New evidence confirms the efficacy of COVID-19 vaccination in cancer patients

The long-awaited confirmation of the efficacy of COVID-19 vaccination in patients with cancer has arrived, on time to be disseminated to a global audience at the annual congress of the European Society for Medical Oncology (ESMO Congress 2021), the leading professional society for medical oncology.

20 Sep 2021

Immunotherapy News and Research

Latest Immunotherapy News and Research

Researchers develop nanoparticles delivering STING agonists for intravenous cancer immunotherapy

Additional supportive care services benefit older adults receiving chemotherapy, study finds

Study reveals how to improve overall immune response against virally driven cancers

Long-held theory of cancer-induced immune suppression requires revision, study says

Researchers compare transcriptomic and cytokine responses of colorectal cancer cells

Research provides the basis for an additional novel immunotherapy for multiple myeloma patients

Study reports on ex vivo drug delivery system for delivering MSCs to kidney disease patients

Classic antidepressants show potential to enhance modern cancer treatments

B cell activating anti-CD73 antibody for the immunotherapy of COVID-19

Novel antibody candidate shows potent binding to diverse SARS-CoV-2 variant mutations

NCI recognizes UC Davis as one of the most elite cancer centers

Promising data from early clinical trials of new anticancer therapies presented at ESMO Congress 2021

AI technique could lead to new ways to predict cancer prognosis and treatment response

Melanomas that metastasize to the adrenal gland are resistant to checkpoint inhibitors

Design of mRNA vaccines to combat COVID-19

Penn Medicine and Wistar secure $11.7 million SPORE grant for three melanoma research projects

Study findings could lead to novel ways to overcome tumor resistance to immunotherapies

Oxford COVID vaccine technology has the potential to revolutionize cancer treatment

Researchers reveal a mechanism of SHP2-mediated tumor immunosuppression

New evidence confirms the efficacy of COVID-19 vaccination in cancer patients

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Immunotherapy News and Research

Latest Immunotherapy News and Research

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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