Inflammatory Bowel Disease News and Research

Latest Inflammatory Bowel Disease News and Research

Higher BMI linked to increased risk of SARS-CoV-2 infection

Researchers at the University of Miami Miller School of Medicine, USA, revealed that the spike-specific immunoglobulin G antibodies in obese people are negatively associated with body mass index (BMI) and serum levels of proinflammatory and metabolic markers of pulmonary inflammation.

24 Dec 2020

Researchers demonstrate potential preventive treatment for Crohn's disease

A potential preventive treatment for Crohn's disease, a form of inflammatory bowel disease, has been demonstrated in a mouse model and using immune-reactive T cells from patients with Crohn's disease.

21 Dec 2020

Mother's diet while breastfeeding can shape the profile of human milk oligosaccharides

Research has shown that human milk is the optimal nutrition source for neonates and infants. It confers protection against both immediately life-threatening infant diseases such as necrotizing enterocolitis, as well as later onset diseases in adults, like obesity, diabetes and inflammatory bowel disease.

16 Dec 2020

Autoimmune condition biomarkers promote SARS-CoV-2 viral entry, study finds

Researchers have reported that the autoimmune PTPN2 risk variant rs1893217 promotes the expression of the SARS-CoV-2 receptor, ACE2, and thus promotes cellular entry, which is mediated by SARS-CoV-2 spike S protein.

16 Dec 2020

Study uncovers genetic risks of Takayasu arteritis

In a paper published today in the American Journal of Human Genetics, a group of international collaborators led by researchers from the University of Pittsburgh School of Medicine identified new genetic associations that can predict individual susceptibility to a rare inflammatory disease called Takayasu arteritis.

11 Dec 2020

Neutrophils may play a key role in COVID-19-related thrombosis

A team of researchers in Italy have published a study suggesting that rather than platelets, neutrophils could be playing the lead role in thrombotic complications associated with COVID-19.

9 Dec 2020

Penn State researcher to study how vitamin D regulates host immunity to viral infection

Funding from the National Institutes of Health will enable a Penn State researcher to study whether vitamin D supplementation could help people ward off or reduce symptoms caused by COVID-19.

24 Nov 2020

Severe COVID-19 complications linked to gut barrier breakdown

A new study claims that severe COVID-19 is caused by a positive feedback loop triggered by systemic inflammation and mediated by abnormal gut permeability. This finding could potentially help open up new avenues of treatment.

18 Nov 2020

Targeting BCAP with new drugs could benefit people with inflammatory bowel disease

Managing the activity of the BCAP protein could help the body repair intestinal tissue from damage caused by inflammation, according to a new study led by experts at Cincinnati Children's.

17 Nov 2020

Study reveals key role of IL-33 signaling molecule in parasite infections, other health conditions

De'Broski Herbert has a philosophy that's guided his career researching helminths, or parasitic worms, and their interaction with their hosts' immune systems: "Follow the worm."

15 Nov 2020

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

Scientists in Taiwan recently published a report on their use of anti-neutrophil strategies to treat acute respiratory distress syndrome (ARDS) – a life-threatening condition that can arise in critical COVID-19 cases – in the journal Frontiers in Pediatrics.

15 Nov 2020

Study identifies genetic risk for fatal blood clots in IBD patients

Blood clots are the biggest cause of death in patients with inflammatory bowel disease (IBD) ─ ulcerative colitis or Crohn's disease. In a retrospective study recently published in the journal Gastroenterology, Cedars-Sinai investigators found that a combination of rare and common genetic variants in some IBD patients significantly increased their risk of developing clot-causing thromboembolic diseases.

11 Nov 2020

Novel super-activating macrophage receptor could explain hyper-inflammation in severe COVID-19

Immunity is a curious thing. While essential in protecting the body against invading pathogens and foreign antigens, it can also turn against the body and trigger destructive immunological processes. A new study published on the preprint server bioRxiv* in November 2020 reports on the role played by hyperactive macrophages in a range of acute and chronic hyper-inflammatory conditions.

10 Nov 2020

Melatonin may be a viable treatment option for COVID-19, study suggests

Results from a new Cleveland Clinic-led study suggest that melatonin, a hormone that regulates the sleep-wake cycle and is commonly used as an over-the-counter sleep aid, may be a viable treatment option for COVID-19.

9 Nov 2020

New IBD safety registry established to support the completion of post-marketing safety requirements

The Pediatric IBD Foundation, ImproveCareNow, and the Critical Path Institute (C-Path) are proud to announce a collaboration establishing the Children's Registry for the Advancement of Therapeutics (CREATE™).

6 Nov 2020

Johns Hopkins researchers design tiny, star-shaped microdevices to deliver drugs

Inspired by a parasitic worm that digs its sharp teeth into its host's intestines, Johns Hopkins researchers have designed tiny, star-shaped microdevices that can latch onto intestinal mucosa and release drugs into the body.

3 Nov 2020

Study suggests a role for the hypothalamus in genetic susceptibility to IBD

Using sophisticated 3D genomic mapping and integrating with public data resulting from genome-wide association studies, researchers at Children's Hospital of Philadelphia have found significant genetic correlations between inflammatory bowel disease and stress and depression.

29 Oct 2020

Severe ulcerative colitis linked to a newly-discovered strain of oral bacteria

Bacteria from the mouth could hold clues to understanding – and potentially treating – severe ulcerative colitis, a painful bowel disease.

29 Oct 2020

High-sugar diet can damage the gut’s protective mucus layer, lead to worse colitis

Mice fed diets high in sugar developed worse colitis, a type of inflammatory bowel disease (IBD), and researchers examining their large intestines found more of the bacteria that can damage the gut's protective mucus layer.

28 Oct 2020

Endocannabinoids in the body can help fight intestinal infections

Endocannabinoids, signaling molecules produced in the body that share features with chemicals found in marijuana, can shut down genes needed for some pathogenic intestinal bacteria to colonize, multiply, and cause disease, new research led by UT Southwestern scientists shows.

7 Oct 2020

Inflammatory Bowel Disease News and Research

Latest Inflammatory Bowel Disease News and Research

Higher BMI linked to increased risk of SARS-CoV-2 infection

Researchers demonstrate potential preventive treatment for Crohn's disease

Mother's diet while breastfeeding can shape the profile of human milk oligosaccharides

Autoimmune condition biomarkers promote SARS-CoV-2 viral entry, study finds

Study uncovers genetic risks of Takayasu arteritis

Neutrophils may play a key role in COVID-19-related thrombosis

Penn State researcher to study how vitamin D regulates host immunity to viral infection

Severe COVID-19 complications linked to gut barrier breakdown

Targeting BCAP with new drugs could benefit people with inflammatory bowel disease

Study reveals key role of IL-33 signaling molecule in parasite infections, other health conditions

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

Study identifies genetic risk for fatal blood clots in IBD patients

Novel super-activating macrophage receptor could explain hyper-inflammation in severe COVID-19

Melatonin may be a viable treatment option for COVID-19, study suggests

New IBD safety registry established to support the completion of post-marketing safety requirements

Johns Hopkins researchers design tiny, star-shaped microdevices to deliver drugs

Study suggests a role for the hypothalamus in genetic susceptibility to IBD

Severe ulcerative colitis linked to a newly-discovered strain of oral bacteria

High-sugar diet can damage the gut’s protective mucus layer, lead to worse colitis

Endocannabinoids in the body can help fight intestinal infections

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

Inflammatory Bowel Disease News and Research

Latest Inflammatory Bowel Disease News and Research

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

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