Inflammatory Bowel Disease News and Research

Latest Inflammatory Bowel Disease News and Research

Mount Sinai researchers reveal innovative mechanisms to predict and prevent Crohn's disease

In a series of four studies published today in Gastroenterology, a journal of the American Gastroenterological Association, Mount Sinai inflammatory bowel disease researchers, describe the identification of predictive tools and a new understanding of environmental factors that trigger IBD.

26 Mar 2020

FDA approves immune-modulating therapy for treatment of multiple sclerosis

The U.S. Food and Drug Administration has approved ozanimod, an immune-modulating therapy invented at Scripps Research, for the treatment of adults with relapsing forms of multiple sclerosis.

26 Mar 2020

Cumulative doses of oral steroids associated with increased hypertension

Cumulative doses of oral steroids in patients with chronic inflammatory diseases are associated with increased hypertension (blood pressure) for those who take them regularly, found new research in CMAJ.

23 Mar 2020

Key COVID-19 information for gastroenterologists and patients with digestive conditions

A paper published today in Clinical Gastroenterology and Hepatology by clinicians at Icahn School of Medicine at Mount Sinai outlines key information gastroenterologists and patients with chronic digestive conditions need to know about COVID-19, or coronavirus.

18 Mar 2020

Using 'organs-on-a-chip' to study chronic inflammatory diseases

MIT biological engineers have created a multitissue model that lets them study the relationships between different organs and the immune system, on a specialized microfluidic platform seeded with human cells.

18 Mar 2020

Immunosuppressive therapy does not increase risk of vulvar or vaginal cancer in women with IBD

In a new retrospective study, researchers found that the use of immunosuppressive therapy does not increase the occurrence or recurrence of vulvar or vaginal cancer in women with inflammatory bowel disease (IBD).

11 Mar 2020

Aging and competition for nutrients determine changes in gut bacteria

Two studies with surprising discoveries: in the elderly, the bacterium E. coli evolves in a way that can become potentially pathogenic and increase the risk of disease and, according to data obtained in another study, the metabolism of the same bacterium present in the microbiota evolves differently if it is alone or accompanied by other bacteria.

11 Mar 2020

New AI system can evaluate endoscopic findings of ulcerative colitis with accuracy

Assessments of patients with ulcerative colitis, which is a type of inflammatory bowel disease, are usually conducted via endoscopy and histology. But now, researchers from Japan have developed a system that may be more accurate than existing methods and may reduce the need for these patients to undergo invasive medical procedures.

6 Mar 2020

Inhibiting specific protein could make radiation therapy for colon cancer more effective

Researchers at Washington University School of Medicine in St. Louis appear to have discovered a way to make radiation therapy for colorectal cancer more effective by inhibiting a protein found in cancer cells in the gut.

3 Mar 2020

Cellular metabolism plays key role in dictating the fate decision between pathogenic and regulatory T cells

Patients with autoimmune diseases like multiple sclerosis, inflammatory bowel disease and rheumatoid arthritis have an imbalance between two types of immune system T cells.

26 Feb 2020

Ulcerative colitis and a missing microbe in the gut

Ulcerative colitis is a seriously debilitating inflammatory disease of the bowel leading to crippling symptoms that can affect the quality of life severely. Researchers from Stanford University School of Medicine have found in a new study that a missing microbe could be linked to this condition. The study was published today in the latest issue of the journal Cell Host & Microbe.

25 Feb 2020

DuPont Nutrition & Biosciences partners with microbiome specialist MRM Health

DuPont Nutrition & Biosciences today announced a collaboration with the MRM Health NV, a biopharmaceutical company, focused on the discovery and development of innovative therapeutics based on the human microbiome.

From DuPont 19 Feb 2020

Microbiome can predict a person's chronological age

Our microbiomes - the complex communities of microbes that live in, on and around us - are influenced by our diets, habits, environments and genes, and are known to change with age.

11 Feb 2020

DNA misfolding linked to heightened risk for Type 1 diabetes

It's known that genetics, or an inherited genome, is a major determinant of one's risk for autoimmune diseases, like Type 1 diabetes. In human cells, a person's genome--about six feet of DNA--is compressed into the micrometer space of the nucleus via a three-dimensional folding process.

11 Feb 2020

Researchers simulate leaky gut conditions using 3D models of human intestines

Once a vague scapegoat for a variety of ills, increasing evidence suggests a condition known as "leaky gut" -- in which microbes and other molecules seep out of the intestines -- may be more common, and more harmful, than previously thought.

10 Feb 2020

Georgia State researcher receives $1.67 million federal grant to study gut immunity

Dr. Tim Denning, professor and associate director of the Institute for Biomedical Sciences at Georgia State University, has received a four-year, $1.67 million federal grant to study how an immunological pathway influences inflammatory signaling in the intestine that can lead to chronic human diseases such as inflammatory bowel disease.

9 Feb 2020

Human organ chips for better drug development

The process of developing new drugs is both difficult and costly. It is estimated that of all the drug candidates which start out on their testing journey, less than 14% actually make it to the clinical scene and receive approval by the US Food and Drug Administration (FDA).

27 Jan 2020

Study reveals new "crosstalk" between intestinal microbes and developing thymic cells

Newborns face unique immunological challenges immediately after birth. As they depart a relatively sterile fetal environment, they are abruptly exposed to a multitude of foreign antigens, the major burden of which is in the form of the microbiota newly colonizing the gastrointestinal tract.

24 Jan 2020

Study reveals new mechanism involved in the pathogenesis of IBD

Inflammatory bowel disease is a category of refractory inflammatory disease, of which ulcerative colitis and Crohn's disease are the main types.

21 Jan 2020

Liver mesenchymal stromal cells could be a better option for many therapeutic applications

Mesenchymal stromal cells from fat tissue and bone marrow are widely used in therapeutic trials for their anti-inflammatory qualities, but new Mayo Clinic research finds that liver cells may be of greater value.

20 Jan 2020

Inflammatory Bowel Disease News and Research

Latest Inflammatory Bowel Disease News and Research

Mount Sinai researchers reveal innovative mechanisms to predict and prevent Crohn's disease

FDA approves immune-modulating therapy for treatment of multiple sclerosis

Cumulative doses of oral steroids associated with increased hypertension

Key COVID-19 information for gastroenterologists and patients with digestive conditions

Using 'organs-on-a-chip' to study chronic inflammatory diseases

Immunosuppressive therapy does not increase risk of vulvar or vaginal cancer in women with IBD

Aging and competition for nutrients determine changes in gut bacteria

New AI system can evaluate endoscopic findings of ulcerative colitis with accuracy

Inhibiting specific protein could make radiation therapy for colon cancer more effective

Cellular metabolism plays key role in dictating the fate decision between pathogenic and regulatory T cells

Ulcerative colitis and a missing microbe in the gut

DuPont Nutrition & Biosciences partners with microbiome specialist MRM Health

Microbiome can predict a person's chronological age

DNA misfolding linked to heightened risk for Type 1 diabetes

Researchers simulate leaky gut conditions using 3D models of human intestines

Georgia State researcher receives $1.67 million federal grant to study gut immunity

Human organ chips for better drug development

Study reveals new "crosstalk" between intestinal microbes and developing thymic cells

Study reveals new mechanism involved in the pathogenesis of IBD

Liver mesenchymal stromal cells could be a better option for many therapeutic applications

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

Inflammatory Bowel Disease News and Research

Latest Inflammatory Bowel Disease News and Research

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

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