Inflammatory Bowel Disease News and Research

Latest Inflammatory Bowel Disease News and Research

Boston researchers develop novel approach to generate intestinal organoids in vitro

Boston researchers have developed a new way to generate groups of intestinal cells that can be used, among others, to make disease models in the lab to test treatments for diseases affecting the gastrointestinal system.

11 Jan 2020

Study: Inflammatory bowel disease can increase certain risks in pregnant women

Pregnant women with inflammatory bowel disease (IBD) are more likely to undergo delivery by Caesarean section and face certain risks during pregnancy, according to an analysis of published studies.

8 Jan 2020

Bile acids could also play a role in immunity and inflammation

Could bile acids--the fat-dissolving juices churned out by the liver and gallbladder--also play a role in immunity and inflammation?

3 Jan 2020

Study finds new drivers of destructive inflammation

Scientists describe in Nature Immunology an entirely new molecular process in mice that triggers T cell-driven inflammation and causes different auto-immune diseases.

17 Dec 2019

Study: Blocking IL1α protein decreases severity of inflammation in Crohn's disease

Investigators at the Case Western Reserve University School of Medicine discovered that blocking interleukin-1α (IL1α), a protein that controls inflammation in the gut, markedly decreases the severity of intestinal inflammation in a mouse model of Crohn's disease (CD).

17 Dec 2019

Scientists develop an approach to vaccinate against gut inflammation

Inflammatory bowel disease (IBD) is an umbrella term that describes many disorders that involve chronic inflammation of the digestive tract, including ulcerative colitis and Crohn's disease. These conditions are tied to certain alternations in the gut flora.

12 Dec 2019

Immune cells repair damaged gut in children with IBD

According to a new study published in the journal Gastroenterology, immune cells of a certain kind which regulate inflammatory processes and even help restore normal gut function after inflammation could be of great use to treat children with inflammatory bowel disease (IBD).

11 Dec 2019

Gut disease and gene analysis networks

Gut diseases are difficult to diagnose in many cases, and their underlying dysfunction is hard to understand in many cases. Now, a new study published in the journal Molecular Omics promises to uncover a better insight into how these conditions occur and their mechanisms, by providing a deeper look at how genes interact in complex ways in health and fail to do so in disease.

11 Dec 2019

New system enables real-time observations of individual cells in the colon

Biomedical engineers at Duke University have developed a system that allows for real-time observations of individual cells in the colon of a living mouse.

11 Dec 2019

Genetically engineered living hydrogel material facilitates intestinal wound healing

About 1.6 million people in the US alone currently have lifelong and incurable Inflammatory Bowel Disease (IBD) including Crohn's disease and ulcerative colitis, and 70,000 new cases are diagnosed in the USA each year.

6 Dec 2019

Young patients with IBD have increased risk of severe viral infections

Young patients with inflammatory bowel disease are five times more likely than the general population to develop viral infections that can lead to hospitalization or permanent organ damage, a new study published in the UEG Journal has found.

5 Dec 2019

FDA-approved drug repairs gut leakiness associated with ulcerative colitis

A research team led by biomedical scientists at the University of California, Riverside, has found that a drug approved by the FDA to treat rheumatoid arthritis and ulcerative colitis can repair permeability defects in the gut's epithelium.

4 Dec 2019

New human colon-on-a-chip enables in vitro study of mucus physiology

We have a mutualistic but complicated relationship with the collection of microbes in our gut known as the intestinal microbiome.

3 Dec 2019

Inhibition of a protease could improve the treatment of IBD, study shows

Scientists at the Centro Nacional de Investigaciones Cardiovasculares and the Centro de Investigaciones Biológicas of the Consejo Superior de Investigaciones Científicas have identified the protease MT1-MMP as a possible future target for drugs to treat inflammatory bowel disease.

3 Dec 2019

Link found between the gut microbiome, host genome, and RA in Japanese population

One of the most astounding discoveries of recent times is just how much influence gut bacteria have on our health and well-being.

2 Dec 2019

Leaky gut and space flight – the mechanism revealed

A new study on the effects of simulated microgravity, the condition that astronauts face in space, interferes with the epithelial barrier of the intestine, and the effect persists even after the astronaut returns to a normal environment. The research is published in the journal Scientific Reports.

28 Nov 2019