Juvenile Diabetes News and Research

Latest Juvenile Diabetes News and Research

Researchers managed to replicate human pancreatic beta cells in mouse model

Klaus Kaestner, PhD, professor of Genetics and postdoctoral fellow Dana Avrahami, PhD, from the Perelman School of Medicine, University of Pennsylvania, published a study this week in the Journal of Clinical Investigation, with colleague Benjamin Glaser, MD, from the Hadassah-Hebrew University Medical Center, Jerusalem, and colleagues. In this study, they were able to replicate human pancreatic beta cells - the cells in our body that produce the critical hormone insulin - in a mouse model in which donor cells were transplanted. The newly replicated cells retained features of mature beta cells and showed a physiological response to glucose.

17 Jan 2014

Oramed reports positive results from ORMD-0801 pharmacokinetic study in type 1 diabetes patients

Oramed Pharmaceuticals Inc., a clinical-stage pharmaceutical company focused on the development of oral drug delivery systems, announced today successful results in a clinical trial testing the pharmacokinetic dose response of its oral insulin capsule (ORMD-0801) in type 1 diabetes patients.

20 Dec 2013

Penn researchers identify protein that could clear Alzheimer's plaques

The body is structured to ensure that any invading organisms have a tough time reaching the brain, an organ obviously critical to survival. Known as the blood-brain barrier, cells that line the brain and spinal cord are tightly packed, making it difficult for anything besides very small molecules to cross from the bloodstream into the central nervous system. While beneficial, this blockade also stands in the way of delivering drugs intended to treat neurological disorders, such as Alzheimer's.

9 Dec 2013

Suppression of mitochondria: A dominant feature of diabetic kidney disease

Researchers at the University of California, San Diego School of Medicine have identified 13 metabolites - small molecules produced by cellular metabolism - that are significantly different in patients with diabetes and chronic kidney disease compared to healthy controls.

11 Oct 2013

Compugen drug candidate prevents autoimmune type I diabetes in animal model

Compugen Ltd., announced today that CGEN-15001, an Fc fusion protein drug candidate derived from a novel immune checkpoint protein discovered by Compugen, has been shown to be highly efficient in preventing the development of disease in a well-accepted animal model of autoimmune type I diabetes, known also as juvenile diabetes.

9 Oct 2013

Salk scientist receives Career Development Award for new research from JDRF

The Juvenile Diabetes Research Foundation has given Salk scientist Mark Huising a five-year, $750,000 Career Development Award for his proposed study on how a novel network of receptors in human islets receives and integrates molecular signals. In pre-clinical models, activation of these receptors has proven to actually prevent diabetes.

9 Oct 2013

Study provides new insights into type 1 diabetes pathology

Joslin researchers have identified immune cells that promote growth of beta cells in type 1 diabetes. This study provides further evidence of a changed role for immune cells in type 1 diabetes pathology. The study appears online today and will also appear in the January issue of Diabetes.

29 Sep 2013

Use of insulin pump with sensor reduces rate of severe hypoglycemia

Use of an insulin pump with a sensor that suspends insulin delivery when blood glucose falls below a set threshold reduced the rate of severe and moderate hypoglycemia among patients with type 1 diabetes and impaired awareness of hypoglycemia, according to a study in the September 25 issue of JAMA.

25 Sep 2013

Vanderbilt examines ability of drug abatacept to prevent type 1 diabetes

Vanderbilt's Eskind Diabetes Clinic has been selected to examine the ability of the drug abatacept to prevent type 1 diabetes (T1D). As part of the TrialNet consortium, Vanderbilt will be one of 14 North American sites observing the effects of the drug in people at high risk to develop T1D.

17 Sep 2013

Drug used in patients for cancer treatment has beneficial effects on diabetes

A pair of studies by researchers at the Stanford University School of Medicine has identified a molecular pathway - a series of interaction among proteins - involved in the development of diabetes. Furthermore, they have found that a drug already approved for use in humans can regulate the pathway.

16 Sep 2013

Little STING could go long way in avoiding arthritis, type 1 diabetes, report researchers

A little STING could go a long way in helping treat or even avoid autoimmune diseases such as arthritis, type 1 diabetes and multiple sclerosis, researchers report.

10 Sep 2013

Experts and patient advocates to discuss growing concerns around blood glucose test strip accuracy

The Diabetes Hands Foundation announced today that it will send diabetes advocate Bennet Dunlap to participate on a panel September 9, 2013 aiming to address the growing concerns around blood glucose test strip accuracy.

7 Sep 2013

UAB study points to protein pathway that could lead to new treatments for diabetes

The same protein tells beta cells in the pancreas to stop making insulin and then to self-destruct as diabetes worsens, according to a University of Alabama at Birmingham study published online today in the journal Nature Medicine.

27 Aug 2013

Teplizumab to block type 1 diabetes proves strikingly effective in phase 2 clinical trial

An experimental drug designed to block the advance of type 1 diabetes in its earliest stages has proven strikingly effective over two years in about half of the patients who participated in the phase 2 clinical trial.

8 Aug 2013

Brain tumor cells in arrested development contribute to cell variety that protects cancer

A program that pushes immature cells to grow up and fulfill their destiny as useful, dedicated cells is short-circuited in the most common and deadly form of brain tumor, scientists at The University of Texas MD Anderson Cancer Center report this week in the Early Edition of the Proceedings of the National Academy of Sciences.

8 Aug 2013

Artificial pancreas for type 1 diabetes patients: an interview with John Pritchard, Cambridge Consultants

Essentially, what an artificial pancreas would be doing is taking the blood glucose results from a continuous monitor and taking the data that the patient puts in about the amount she/he is eating, and then adjusting the amount of insulin being delivered by the pump based on a mathematical formula that would be very personalized to that patient.

25 Jul 2013

Researchers discover potential markers for severity of juvenile idiopathic arthritis

Children who suffer from arthritis could one day receive more targeted treatment thanks to potential markers for the severity of the disorder discovered by researchers at the University of Adelaide and Women's and Children's Hospital.

15 Jul 2013

NIH awards nursing students of Wayne State University to gain unique insight about research fields

Eight Wayne State University undergraduate nursing students are gaining unique insight about the research field thanks to a $40,000 grant awarded to the university's College of Nursing and School of Medicine from the National Institute of Nursing Research of the National Institutes of Health.

3 Jul 2013

UCI researchers receive $2.27M to develop innovative methods of treating Type 1 diabetes.

Two UC Irvine research groups have received $2.27 million from the JDRF to develop innovative methods of treating and possibly curing Type 1 diabetes.

27 Jun 2013

Researchers are one step closer to treating type 1 diabetes

Researchers at Washington University School of Medicine in St. Louis have identified a way to trigger reproduction in the laboratory of clusters of human cells that make insulin, potentially removing a significant obstacle to transplanting the cells as a treatment for patients with type 1 diabetes.

14 Jun 2013

Juvenile Diabetes News and Research

Latest Juvenile Diabetes News and Research

Researchers managed to replicate human pancreatic beta cells in mouse model

Oramed reports positive results from ORMD-0801 pharmacokinetic study in type 1 diabetes patients

Penn researchers identify protein that could clear Alzheimer's plaques

Suppression of mitochondria: A dominant feature of diabetic kidney disease

Compugen drug candidate prevents autoimmune type I diabetes in animal model

Salk scientist receives Career Development Award for new research from JDRF

Study provides new insights into type 1 diabetes pathology

Use of insulin pump with sensor reduces rate of severe hypoglycemia

Vanderbilt examines ability of drug abatacept to prevent type 1 diabetes

Drug used in patients for cancer treatment has beneficial effects on diabetes

Little STING could go long way in avoiding arthritis, type 1 diabetes, report researchers

Experts and patient advocates to discuss growing concerns around blood glucose test strip accuracy

UAB study points to protein pathway that could lead to new treatments for diabetes

Teplizumab to block type 1 diabetes proves strikingly effective in phase 2 clinical trial

Brain tumor cells in arrested development contribute to cell variety that protects cancer

Artificial pancreas for type 1 diabetes patients: an interview with John Pritchard, Cambridge Consultants

Researchers discover potential markers for severity of juvenile idiopathic arthritis

NIH awards nursing students of Wayne State University to gain unique insight about research fields

UCI researchers receive $2.27M to develop innovative methods of treating Type 1 diabetes.

Researchers are one step closer to treating type 1 diabetes

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Juvenile Diabetes News and Research

Latest Juvenile Diabetes News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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