Melanoma News and Research

Latest Melanoma News and Research

Scientists identify factors influencing outcomes in kidney cancer patients treated with immunotherapy

By analyzing tumors from patients treated with immunotherapy for advanced kidney cancer in three clinical trials, Dana-Farber Cancer Institute scientists have identified several features of the tumors that influence their response to immune checkpoint inhibitor drugs.

30 May 2020

First-ever oncology hospital-at-home program shows improved patient outcomes

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) presented the first outcomes evaluation of an adult oncology hospital-at-home program today at the 2020 American Society of Clinical Oncology (ASCO) annual meeting.

30 May 2020

Newer treatment approaches may reduce risk of therapy-related hematologic cancers

While breakthrough treatments have emerged for several cancers over the last two decades, driving striking improvements in survival and other clinical outcomes, too little is known about the risk of therapy-related hematologic cancers following targeted and immunotherapeutic approaches.

29 May 2020

First-ever oncology hospital-at-home program improves patient outcomes, reduces hospitalizations

Researchers at Huntsman Cancer Institute at the University of Utah (U of U) presented the first outcomes evaluation of an adult oncology hospital-at-home program today at the 2020 American Society of Clinical Oncology annual meeting.

29 May 2020

Adoptive T-cell therapy targeting MAGE-A4 achieves responses in patients with multiple solid tumors

The adoptive T-cell therapy ADP-A2M4, which is engineered to express a T-cell receptor (TCR) directed against the MAGE-A4 cancer antigen, achieved responses in patients with multiple solid tumor types, including synovial sarcoma, head and neck cancer and lung cancer, according to results from a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

29 May 2020

Ludwig Cancer Research study profiles immune landscape of brain tumors

A Ludwig Cancer Research study has profiled, in a sweeping comparative analysis, the distinct immune landscapes of tumors that arise in the brain, or gliomas, and those that metastasize to the organ from the lungs, breast and skin.

28 May 2020

Inhibiting tumor signals can suppress the spread of cancer

For most people who die of cancer, the spread of the initial tumor is to blame. "Metastasis is what kills most cancer patients," says Serge Fuchs, a professor in Penn's School of Veterinary Medicine.

28 May 2020

New drug combinations could help overcome genetic immunotherapy resistance

A new study from researchers at the UCLA Jonsson Comprehensive Cancer Center helps explain how disruptions in genes can lead to the resistance to one of the leading immunotherapies, PD-1 blockade, and how new drug combinations could help overcome resistance to the anti-PD-1 therapy in a mechanistically-based way.

28 May 2020

A new approach to predict the evolutionary mechanisms of melanoma

Melanoma is a malignant tumour resulting from the transformation of melanocytes, the cells in the skin that undertake to synthesise melanin, a complex polymer which protects us from the negative effects of solar radiation.

27 May 2020

Antimalarial drug shows promise as potential therapy for aggressive brain cancer

Glioblastoma multiforme is an aggressive form of cancer in the brain that is typically fatal. But new findings by VCU Massey Cancer Center and VCU Institute of Molecular Medicine researchers could help increase the effectiveness of the most common current treatments with the addition of lumefantrine, an FDA-approved drug used to treat malaria.

26 May 2020

Inherited genetic variations can alter progression of melanoma, indicates study

Sometimes cancer stays put, but often it metastasizes, spreading to new locations in the body. It has long been suspected that genetic mutations arising inside tumor cells drive this potentially devastating turn of events.

26 May 2020

Scientists discover how an obscure protein promotes breast cancer progression

South Australian scientists have made a critical breakthrough, discovering how an obscure protein causes breast cancer to develop and grow more quickly.

25 May 2020

Study examines 5-aminolevulinic acid induced fluorescence in surgery of brain metastases

Two-thirds of brain metastases give off fluorescence following administration of 5-aminolevulinic acid, which could potentially assist surgeons in identifying such tumors.

20 May 2020

Placentas of pregnant women with COVID-19 showed abnormalities

A study conducted by researchers at Northwestern University, Chicago, has found that the placentas of pregnant women who were infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) showed abnormalities, compared with those of uninfected women.

13 May 2020

Innovative approach turns 'cold' tumors 'hot' to improve cancer immunotherapy

Scientists from the Tumor Immunotherapy and Microenvironment research group led by Dr Bassam Janji at the Luxembourg Institute of Health Department of Oncology, and the Swedish pharma company Sprint Bioscience published the results of an innovative approach that turns “cold” tumors “hot”. “Cold”, immune-desert tumors are classically immunotherapy-resistant.

13 May 2020

New review outlines potential approaches for treating cold tumors

Announcing a new article publication for BIO Integration journal. In this review article the authors Jing Liu, Mengze Xu and Zhen Yuan from University of Macau, Macau SAR, China consider immunotherapy for the treatment of tumors.

13 May 2020

Fasting-mimicking diet plus vitamin C could be effective at treating some cancer types

Scientists from USC and the IFOM Cancer Institute in Milan have found that a fasting-mimicking diet could be more effective at treating some types of cancer when combined with vitamin C.

12 May 2020

Common allergy medicine may improve survival in patients with malignant melanoma

Can a very common allergy medicine improve survival among patients suffering from the serious skin cancer, malignant melanoma? A new study from Lund University in Sweden indicates that this may be the case.

11 May 2020

Interleukin-12 electroporation led to clinical responses in patients with advanced melanoma

Combining intratumoral electroporation of interleukin-12 (IL-12) DNA (tavokinogene telseplasmid, or TAVO) with the immune checkpoint inhibitor pembrolizumab (Keytruda) led to clinical responses in patients with immunologically quiescent advanced melanoma, according to results from a phase II trial.

6 May 2020

Activation of estrogen receptor can impede growth of pancreatic cancer cells

Activating the G protein-coupled estrogen receptor - a receptor found on the surface of many normal and cancer tissues - has been shown to stop pancreatic cancer from growing, but may also make tumors more visible to the immune system and thus more susceptible to modern immunotherapy.

4 May 2020

Melanoma News and Research

Latest Melanoma News and Research

Scientists identify factors influencing outcomes in kidney cancer patients treated with immunotherapy

First-ever oncology hospital-at-home program shows improved patient outcomes

Newer treatment approaches may reduce risk of therapy-related hematologic cancers

First-ever oncology hospital-at-home program improves patient outcomes, reduces hospitalizations

Adoptive T-cell therapy targeting MAGE-A4 achieves responses in patients with multiple solid tumors

Ludwig Cancer Research study profiles immune landscape of brain tumors

Inhibiting tumor signals can suppress the spread of cancer

New drug combinations could help overcome genetic immunotherapy resistance

A new approach to predict the evolutionary mechanisms of melanoma

Antimalarial drug shows promise as potential therapy for aggressive brain cancer

Inherited genetic variations can alter progression of melanoma, indicates study

Scientists discover how an obscure protein promotes breast cancer progression

Study examines 5-aminolevulinic acid induced fluorescence in surgery of brain metastases

Placentas of pregnant women with COVID-19 showed abnormalities

Innovative approach turns 'cold' tumors 'hot' to improve cancer immunotherapy

New review outlines potential approaches for treating cold tumors

Fasting-mimicking diet plus vitamin C could be effective at treating some cancer types

Common allergy medicine may improve survival in patients with malignant melanoma

Interleukin-12 electroporation led to clinical responses in patients with advanced melanoma

Activation of estrogen receptor can impede growth of pancreatic cancer cells

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Melanoma News and Research

Latest Melanoma News and Research

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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