Metabolism News and Research

Latest Metabolism News and Research

Key enzyme may be therapeutic target to treat diabetes-related blood vessel damage

A key enzyme that helps our proteins fold and function properly may also be a good therapeutic target to improve blood vessel health in diseases like diabetes and atherosclerosis, scientists say.

23 Oct 2017

Researchers discover new regulatory role for protein that links diet and disease

A team of researchers from Case Western Reserve University School of Medicine have discovered how uncontrolled vitamin A metabolism in the gut can cause harmful inflammation.

23 Oct 2017

Penn researchers provide new insights into how Notch drives growth of B-cell cancers

Notch is one of the most frequently mutated genes in chronic lymphocytic leukemia (CLL), the most common leukemia in adults in the United States. It is also often mutated in other common B cell tumors, such as mantle cell lymphoma.

23 Oct 2017

Blood levels of thyroid hormone may help identify individuals at risk for irregular heartbeat

Individuals with higher levels of thyroid hormone (free thyroxine, FT4) circulating in the blood were more likely than individuals with lower levels to develop irregular heartbeat, or atrial fibrillation, even when the levels were within normal range, according to new research in the American Heart Association's journal Circulation.

23 Oct 2017

Study elucidates how obesity makes breast cancer more aggressive

Obesity leads to the release of cytokines into the bloodstream which impact the metabolism of breast cancer cells, making them more aggressive as a result. Scientists from Helmholtz Zentrum München, Technische Universität München, and Heidelberg University Hospital report on this in 'Cell Metabolism'. The team has already been able to halt this mechanism with an antibody treatment.

23 Oct 2017

New study adds evidence to ‘selfish brain’ theory of human evolution

Human brains are expensive - metabolically speaking. It takes lot of energy to run our sophisticated grey matter, and that comes at an evolutionary cost.

23 Oct 2017

Better post-weaning diet can reverse potential consequences of early-life high-fat exposure

Research has shown that a mother's diet during pregnancy, particularly one that is high-fat, may program her baby for future risk of certain diseases such as diabetes. A new study from nutrition researchers at the University of Illinois shows that switching the offspring to a new diet--a low-fat diet, in this case--can reverse that programming.

20 Oct 2017

Small RNA molecules trigger cancer cells to commit suicide

Small RNA molecules originally developed as a tool to study gene function trigger a mechanism hidden in every cell that forces the cell to commit suicide, reports a new Northwestern Medicine study, the first to identify molecules to trigger a fail-safe mechanism that may protect us from cancer.

19 Oct 2017

Scientists uncover surprising molecular link in critical cellular growth pathway

A team of scientists led by Whitehead Institute has uncovered a surprising molecular link that connects how cells regulate growth with how they sense and make available the nutrients required for growth.

19 Oct 2017

Yale study finds reduced brain glucose levels in people with obesity, type 2 diabetes

Glucose levels are reduced in the brains of individuals with obesity and type 2 diabetes compared to lean individuals, according to a new Yale study. The finding might explain disordered eating behavior -- and even a higher risk of Alzheimer's disease -- among obese and diabetic individuals, the researchers said.

19 Oct 2017

New imaging system offers better way to monitor brain changes from Alzheimer's in mouse models

An estimated 5.5 million Americans live with Alzheimer's disease, a type of dementia that causes problems with memory, thinking and behavior. Although treatments can slow the worsening of symptoms, scientists are still working to better understand the neurodegenerative disease so that curative and preventative medicines can be developed.

17 Oct 2017

Lack of sleep among pregnant women linked to increased risk of gestational diabetes

The amount of time spent sleeping in the United States has dropped significantly in the past twenty years with almost a quarter of women and 16 percent of men experiencing insufficient sleep. Now, a new study has found that lack of sleep among pregnant women may be a contributing factor to the development of gestational diabetes.

16 Oct 2017

New model predicts how E. coli bacteria respond to temperature changes, genetic mutations

Researchers at the University of California San Diego have developed a genome-scale model that can accurately predict how E. coli bacteria respond to temperature changes and genetic mutations.

13 Oct 2017

Breakthrough discovery reveals positive correlation between sugar and cancer

A nine-year joint research project conducted by VIB, KU Leuven and VUB has led to a crucial breakthrough in cancer research.

13 Oct 2017

Cholesterol byproduct acts on specific immune cells to facilitate breast cancer spread

High cholesterol levels have been associated with breast cancer spreading to other sites in the body, but doctors and researchers don't know the cause for the link.

12 Oct 2017

MIT researchers develop new technique to screen for genes that protect against diseases

Using a modified version of the CRISPR genome-editing system, MIT researchers have developed a new way to screen for genes that protect against specific diseases.

12 Oct 2017

New study examines link between sleep and weight management

A new study by sleep experts at Loughborough University is examining how sleep and weight management are related.

12 Oct 2017

C-section kids could be at greater risk of being overweight due to differences in their gut bacteria

Researchers from NYU School of Medicine studied the effects of Caesarean section on the weights of the offspring in laboratory mice and found that they are more at risk of becoming overweight and obese.

12 Oct 2017

Study pinpoints racial disparities linked to severity and effects of peripartum cardiomyopathy

African American women were found to be twice as likely to be diagnosed with peripartum cardiomyopathy as compared to women of Caucasian, Hispanic/Latina, Asian, and other ethnic backgrounds, according to a new study--the largest of its kind--published today in JAMA Cardiology by researchers from the Perelman school of Medicine at the University of Pennsylvania.

11 Oct 2017

Penn State researcher creates step-index optical fiber for light delivery inside the body

A flexible, biodegradable optical fiber that can deliver light into the body for medical applications is the latest work of a collaboration between electrical engineers and biomaterials engineers in Penn State's Materials Research Institute.

11 Oct 2017

Metabolism News and Research

Latest Metabolism News and Research

Key enzyme may be therapeutic target to treat diabetes-related blood vessel damage

Researchers discover new regulatory role for protein that links diet and disease

Penn researchers provide new insights into how Notch drives growth of B-cell cancers

Blood levels of thyroid hormone may help identify individuals at risk for irregular heartbeat

Study elucidates how obesity makes breast cancer more aggressive

New study adds evidence to ‘selfish brain’ theory of human evolution

Better post-weaning diet can reverse potential consequences of early-life high-fat exposure

Small RNA molecules trigger cancer cells to commit suicide

Scientists uncover surprising molecular link in critical cellular growth pathway

Yale study finds reduced brain glucose levels in people with obesity, type 2 diabetes

New imaging system offers better way to monitor brain changes from Alzheimer's in mouse models

Lack of sleep among pregnant women linked to increased risk of gestational diabetes

New model predicts how E. coli bacteria respond to temperature changes, genetic mutations

Breakthrough discovery reveals positive correlation between sugar and cancer

Cholesterol byproduct acts on specific immune cells to facilitate breast cancer spread

MIT researchers develop new technique to screen for genes that protect against diseases

New study examines link between sleep and weight management

C-section kids could be at greater risk of being overweight due to differences in their gut bacteria

Study pinpoints racial disparities linked to severity and effects of peripartum cardiomyopathy

Penn State researcher creates step-index optical fiber for light delivery inside the body

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