Metabolism News and Research

Latest Metabolism News and Research

Chemicals used in plastics linked to increased risk of high blood pressure, diabetes in children and adolescents

According to a new series of studies out of NYU Langone Medical Center, two chemicals increasingly used during manufacturing to strengthen plastic wrap, soap, cosmetics, and processed food containers have been linked to a rise in risk of high blood pressure and diabetes in children and adolescents.

9 Jul 2015

Simple blood test could detect early stages of type 1 diabetes

Scientists at the MRC's Clinical Sciences Centre in West London are the first to show that a small molecule circulates in the blood of people who are in the early stages of type 1 diabetes. A simple blood test could detect this biological marker years, maybe decades, before symptoms develop.

9 Jul 2015

City of Hope offers islet cell transplant program to cure type 1 diabetes

For patients with severe type 1 diabetes, a strict diet and insulin shots are sometimes not enough to sufficiently control their disease. What they need are insulin-producing cells of their own - currently only available through a still-experimental procedure known as islet cell transplantation.

8 Jul 2015

WSU researcher secures $1.25 million NIH grant to study role of rosiglitazone drug in reversing preeclampsia

Sascha Drewlo, Ph.D., assistant professor of obstetrics and gynecology for the Wayne State University School of Medicine, has secured a $1.25 million grant from the National Heart, Lung and Blood Institute of the National Institutes of Health to study the role of approved drugs to improve placental function.

8 Jul 2015

MGH-CEM researchers develop microfabricated device to analyze effects of pro-drugs on cancer cells

A team of researchers from the Massachusetts General Hospital Center for Engineering in Medicine has developed a novel approach that dramatically simplifies the evaluation of the liver's drug-metabolizing activity and the potential toxic effects of the products of that activity on other organs.

8 Jul 2015

Cognizin citicoline shows promise in patients with bipolar disorder and cocaine dependence

The results of a randomized, double-blind, placebo-controlled clinical trial showed that Cognizin citicoline (Jarrow Formulas) was effective at reducing cocaine use, based on urine drug screens, in patients with bipolar disorder and cocaine dependence. The study, published in the American Journal of Psychiatry in Advance, included a total of 130 outpatients with bipolar I disorder and cocaine dependence, who received either Cognizin citicoline or placebo add-on therapy for 12 weeks.

7 Jul 2015

Tests reveal that FY26 cancer drug is 49 times more potent than Cisplatin drug

Tests have shown that a new cancer drug, FY26, is 49 times more potent than the clinically used treatment Cisplatin.

7 Jul 2015

New treatment option available for CLL patients in Manitoba and Saskatchewan

People in Manitoba and Saskatchewan living with Chronic Lymphocytic Leukemia (CLL) will now be able to access a new treatment option through the prescription drug insurance plans in both provinces. Earlier this week, GAZYVA (obinutuzumab) in combination with chlorambucil chemotherapy was added to benefits formularies of the Provincial Oncology Drug Programs at CancerCare Manitoba and the Saskatchewan Cancer Agency.

6 Jul 2015

Penn study suggests future precision medicine approach to treating diabetes, other metabolic disorders

In the first study of its kind, Penn researchers have shown how an anti-diabetic drug can have variable effects depending on small natural differences in DNA sequence between individuals. Mitchell Lazar, MD, PhD, Raymond Soccio, MD, PhD, and colleagues at the Perelman School of Medicine at the University of Pennsylvania, aim to apply this knowledge to develop personalized approaches to treating diabetes and other metabolic disorders.

3 Jul 2015

More support for amyloidosis as earliest AD biomarker

A longitudinal study of people with autosomal dominant Alzheimer’s disease shows that β-amyloid deposition begins well before neurodegeneration and cognitive decline.

2 Jul 2015

European Nanomedicine Characterization Lab aims to bring safe, efficient nano-therapeutics to patients

Empa, the Swiss Federal Laboratories for Materials Science and Technology, is part of the European Nanomedicine Characterization Laboratory, a European project funded by the EU framework program «Horizon 2020.

2 Jul 2015

UTHealth researchers discover new light-activated proteins that work as 'off switches' for brain cells

Light switches for neurons have made enormous contributions to brain research by giving investigators access to "on switches" for brain cells. But, finding "off switches" has been much more challenging.

2 Jul 2015

Special issue provides comprehensive overview of latest findings in the area of skeletal research

While there is good understanding of how bone mass, and more recently bone architecture, affects fracture risk, far less is known about the material properties of bone, or how these can impart resilience or fragility to the skeleton.

2 Jul 2015

Concert Pharmaceuticals’ precision deuteration platform can enhance metabolic properties of drugs

Substituting deuterium for certain hydrogen atoms in molecules has been shown to enhance the metabolic properties of a number of drugs and provides a promising approach to the discovery and development of innovative drug products.

2 Jul 2015

Multiple courses of antibiotics may have significant impact on child development

A new animal study by NYU Langone Medical Center researchers adds to growing evidence that multiple courses of commonly used antibiotics may have a significant impact on children's development.

1 Jul 2015

New York Blue Light Symposium highlights three measures to counter consequences of artificial illumination

The New York Blue Light Symposium convened in New York from June 26-27, 2015. The event was sponsored by the International Blue Light Society (Senior Representative: Kazuo Tsubota), which was founded to research and release findings on the effects of blue light on the human body.

30 Jun 2015

Inhibikase Therapeutics receives Phase II SBIR grant to advance novel RAMP medicinal chemistry program

Inhibikase Therapeutics, Inc. announces the receipt of a Phase II SBIR grant in the amount of $1.54 million dollars from the U.S. National Institutes of Health to advance its novel Re-engineering with Metabolism Preserved (RAMP) medicinal chemistry program.

29 Jun 2015

Researchers discover mechanism that regulates metabolism

The protein complex mTORC1 is a central regulator of cell metabolism. In the active state, it stimulates anabolic processes and increases the production and storage of proteins and lipids. Researchers from the German Leibniz Institute for Age Research in Jena and the Dutch Ageing Institute ERIBA in Groningen discovered a mechanism how mTORC1 regulates metabolism: It controls the expression of a specific variant of the transcriptional regulator C/EBPβ.

29 Jun 2015

SLU researchers find way to stop growth of cancer cells by targeting the Warburg Effect

In research published in Cancer Cell, Thomas Burris, Ph.D., chair of pharmacology and physiology at Saint Louis University, has, for the first time, found a way to stop cancer cell growth by targeting the Warburg Effect, a trait of cancer cell metabolism that scientists have been eager to exploit.

26 Jun 2015

Potential new class of drugs lessen neurodegeneration in rat model of Parkinson's disease

The first test in a mammalian model of a potential new class of drugs to treat Parkinson's disease shows abatement of neurodegeneration in the brains of test rats and no significant toxicities, University of Alabama at Birmingham and Pfizer Inc. researchers report online in The Journal of Biological Chemistry.

26 Jun 2015

Metabolism News and Research

Latest Metabolism News and Research

Chemicals used in plastics linked to increased risk of high blood pressure, diabetes in children and adolescents

Simple blood test could detect early stages of type 1 diabetes

City of Hope offers islet cell transplant program to cure type 1 diabetes

WSU researcher secures $1.25 million NIH grant to study role of rosiglitazone drug in reversing preeclampsia

MGH-CEM researchers develop microfabricated device to analyze effects of pro-drugs on cancer cells

Cognizin citicoline shows promise in patients with bipolar disorder and cocaine dependence

Tests reveal that FY26 cancer drug is 49 times more potent than Cisplatin drug

New treatment option available for CLL patients in Manitoba and Saskatchewan

Penn study suggests future precision medicine approach to treating diabetes, other metabolic disorders

More support for amyloidosis as earliest AD biomarker

European Nanomedicine Characterization Lab aims to bring safe, efficient nano-therapeutics to patients

UTHealth researchers discover new light-activated proteins that work as 'off switches' for brain cells

Special issue provides comprehensive overview of latest findings in the area of skeletal research

Concert Pharmaceuticals’ precision deuteration platform can enhance metabolic properties of drugs

Multiple courses of antibiotics may have significant impact on child development

New York Blue Light Symposium highlights three measures to counter consequences of artificial illumination

Inhibikase Therapeutics receives Phase II SBIR grant to advance novel RAMP medicinal chemistry program

Researchers discover mechanism that regulates metabolism

SLU researchers find way to stop growth of cancer cells by targeting the Warburg Effect

Potential new class of drugs lessen neurodegeneration in rat model of Parkinson's disease

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications