Metabolism News and Research

Latest Metabolism News and Research

Common diabetes drug could be repurposed as a treatment for autoimmune disorders

Swansea University researchers have found that a drug commonly used to treat type 2 diabetes can potentially be used in the treatment of autoimmune disorders.

25 May 2023

Researchers design new tool to remove clinician barriers in providing weight management care

After finding that few to no clinicians provided weight management care, researchers developed a weight loss tool called PATHWEIGH.

24 May 2023

Looking at cancer drugs to help put the brakes on classic indicators of aging

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

Innovative magnetic muscle therapy could reverse decline in functional mobility, loss of muscle strength in older adults

A decline in functional mobility, loss of muscle strength and an increase in body fats are often associated with aging.

23 May 2023

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Research unveils the significance of uridine as a metabolic fuel in pancreatic ductal adenocarcinoma (PDA) cells under glucose-deprived conditions. Uridine utilization, mediated by uridine phosphorylase 1 (UPP1), supports redox balance, survival, and proliferation in PDA, highlighting its potential as a novel therapeutic target in the treatment of this resistant cancer.

23 May 2023

Metabolic sensors may play a role in the development of Alzheimer's disease, study suggests

It's well-known that people with Type 2 diabetes are at an increased risk of developing Alzheimer's disease, but the reason why isn't fully understood and is an area of current research.

22 May 2023

High HDL-C levels and cardiovascular risks - what you need to know!

Research paper investigates the relationship between very high levels of high-density lipoprotein cholesterol (HDL-C) and cardiovascular outcomes in the general population. The study reveals that while men with high HDL-C face an increased risk of all-cause death and cardiovascular death, this association is not observed in women without coronary artery disease.

22 May 2023

Surviving without glucose: uridine-derived ribose as an alternative energy source

Researchers attempted to identify new genes and molecular pathways that might supply energy when the availability of glucose or other nutrients is limited.

22 May 2023

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The clinical outcomes of patients with active RA can be improved using anti-rheumatic medications, such as methotrexate (MTX).

22 May 2023

Study could help understand why limiting sugary foods can ease symptoms for IBD patients

Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study by University of Pittsburgh scientists.

22 May 2023

AI-based method predicts small molecule substrates of enzymes

Enzymes are the molecule factories in biological cells. However, which basic molecular building blocks they use to assemble target molecules is often unknown and difficult to measure.

22 May 2023

People with higher long-term hair glucocorticoid levels more likely to develop heart, circulatory diseases

New research being presented at this year's European Congress on Obesity (ECO) in Dublin, Ireland (17-20 May) suggests that glucocorticoid levels (a class of steroid hormones secreted as a response to stress) present in the hair of individuals may indicate which of them are more likely to suffer from cardiovascular diseases (CVD) in the future.

22 May 2023

Indirect inhibitors of cellular respiration for treatment of glioblastoma

A new research perspective was published in Oncotarget's Volume 14 on May 4, 2023, entitled, "Targeting cellular respiration as a therapeutic strategy in glioblastoma."

19 May 2023

Genomes of modern humans shaped by admixture events

The course of human history has been marked by complex patterns of migration, isolation, and admixture, the latter a term that refers to gene flow between individuals from different populations.

19 May 2023

Tirzepatide improves body composition across a range of adult age groups, study shows

A new analysis of SURMOUNT-1, the first Phase 3 study of tirzepatide in adults for chronic weight management shows that tirzepatide improves body composition across a range of adult age groups.

19 May 2023

Mutation in a ribosomal protein leads to impaired cardiac contractility in mice

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.

19 May 2023

Transforming antibiotic resistance testing: a novel, rapid and affordable technique

News Medical speaks with Dr. Sandor Kasas, a lead researcher at Ecole Polytechnique Fédérale de Lausanne in Switzerland.

19 May 2023

Going nuts for heart health: Mixed nuts consumption shows promising effects on cardiovascular risk factors

Researchers investigated the effect of daily consumption of mixed nuts on cardiovascular disease biomarkers in overweight and obese adults.

18 May 2023

Researchers discover how corticosteroids influence inflammatory response during COVID-19 infection

Since the start of the COVID-19 pandemic, a class of corticosteroids called glucocorticoids (GCs) have become established as one of the main treatment options, especially for severe cases, thanks to their anti-inflammatory and immunosuppressant action.

18 May 2023

Researchers discover molecular pathway that mediates cancer-associated muscle atrophy

Nearly half of all cancer patients suffer from excessive weight loss due to the loss of adipose and skeletal muscle tissues, or cachexia.

18 May 2023

Metabolism News and Research

Latest Metabolism News and Research

Common diabetes drug could be repurposed as a treatment for autoimmune disorders

Researchers design new tool to remove clinician barriers in providing weight management care

Looking at cancer drugs to help put the brakes on classic indicators of aging

Innovative magnetic muscle therapy could reverse decline in functional mobility, loss of muscle strength in older adults

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Metabolic sensors may play a role in the development of Alzheimer's disease, study suggests

High HDL-C levels and cardiovascular risks - what you need to know!

Surviving without glucose: uridine-derived ribose as an alternative energy source

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

Study could help understand why limiting sugary foods can ease symptoms for IBD patients

AI-based method predicts small molecule substrates of enzymes

People with higher long-term hair glucocorticoid levels more likely to develop heart, circulatory diseases

Indirect inhibitors of cellular respiration for treatment of glioblastoma

Genomes of modern humans shaped by admixture events

Tirzepatide improves body composition across a range of adult age groups, study shows

Mutation in a ribosomal protein leads to impaired cardiac contractility in mice

Transforming antibiotic resistance testing: a novel, rapid and affordable technique

Going nuts for heart health: Mixed nuts consumption shows promising effects on cardiovascular risk factors

Researchers discover how corticosteroids influence inflammatory response during COVID-19 infection

Researchers discover molecular pathway that mediates cancer-associated muscle atrophy

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production