Metabolomics News and Research

Latest Metabolomics News and Research

Pharmacophore model helps find key protease inhibitor responsible for COVID-19

A team of San Diego Supercomputer Center (SDSC) researchers recently created a pharmacophore model and conducted data mining of the database of drugs approved by the U.S. Federal Drug Administration (FDA) to find potential inhibitors of papain-like protease of SARS-CoV2, one of the main viral proteins responsible for COVID-19.

2 Dec 2020

Severe COVID-19 complications linked to gut barrier breakdown

A new study claims that severe COVID-19 is caused by a positive feedback loop triggered by systemic inflammation and mediated by abnormal gut permeability. This finding could potentially help open up new avenues of treatment.

18 Nov 2020

Short bursts of exercise elicit widespread changes in the body's levels of metabolites

Short bursts of physical exercise induce changes in the body's levels of metabolites that correlate to, and may help gauge, an individual's cardiometabolic, cardiovascular and long-term health, a study by Massachusetts General Hospital has found.

16 Nov 2020

Compound found in brown seaweeds could help treat malignant brain tumour

A compound found in brown seaweeds could help to treat one of the most common and aggressive forms of malignant brain tumour.

10 Nov 2020

High Throughput Identification and Quantification of Breast Cancer With NMR-Based Metabolomics

Breast cancer is the leading cause of cancer-related death among the female population globally, despite the ever-growing technology of early detection.

From Bruker BioSpin - NMR, EPR and Imaging 30 Oct 2020

Study findings could lead to a rapid, cost-effective screening tool for COVID-19

A new study from Lawson Health Research Institute, Western University and University of Alberta suggests that COVID-19 affects the human body's blood concentration levels of specific metabolites - small molecules broken down in the human body through the process of metabolism.

27 Oct 2020

NMR Metabolomics as Novel Screening Tool for New-borns (For Research Only)

In this interview, Oscar Millet, group leader of the Precision Medicine and Metabolism group of the CIC bioGUNE, talked to News Medical about his research into the use of nuclear magnetic resonance spectroscopy (NMR) metabolomic analysis as a clinical screening tool. His team has used NMR to screen urine samples form new-borns for congenital metabolic disorders.

From Bruker BioSpin - NMR, EPR and Imaging 20 Oct 2020

Serum metabolite profile can help identify individuals at risk of alcohol-related disease

A new study from the University of Eastern Finland is the first in the world to show that the serum metabolite profile can be used to identify individuals likely at risk of developing an alcohol-related disease in the future.

19 Oct 2020

New machine learning concepts can help develop novel drugs

Tandem mass spectrometry is a powerful analytical tool used to characterize complex mixtures in drug discovery and other fields.

14 Oct 2020

Too little sugar is the cause of perforated bones

Bone marrow cancer is currently an incurable disease that affects about 400 people in Norway every year. Professor Therese Standal at NTNU has now found an important reason for bone destruction in people with this disease.

9 Oct 2020

UCLA researchers receive $13 million NIH grant to combat melanoma

UCLA researchers have received a $13 million grant from the National Institutes of Health to find new ways to overcome melanoma resistance to some of the most promising targeted therapies and immunotherapies.

28 Sep 2020

New framework allows researchers to probe the metabolic processes inside cancer cells

One of the biggest challenges to the development of medical treatments for cancer is the fact that there is no single kind of cancer.

28 Sep 2020

NAU researcher awarded $3.75 million NCI grant to build cancer research software

Greg Caporaso, director of the Center for Applied Microbiome Science, part of the Pathogen and Microbiome Institute at Northern Arizona University, has been awarded a $3.75 million grant by the National Cancer Institute to build software capable of analyzing and archiving data focused on the interplay between the human microbiome (the trillions of microorganisms living in and on the human body) and diverse types of cancer.

22 Sep 2020

Heat and gut microbiota promote stronger bones

Osteoporosis, a bone disease linked to ageing, is characterized by a loss of bone density, micro-architectural deterioration of the bones and an increased risk of fractures.

11 Sep 2020

CN Bio partners with Imperial College London to uncover therapeutic targets for alcoholic hepatitis

CN Bio, a leading cell culture company, that has developed single and multi-organ microphysiological systems to improve the accuracy and efficiency of drug discovery, today announced a collaboration with Imperial College London, a world-class research university.

10 Sep 2020

Exploring the Relationship Between Mass Spectrometry and Informatics

Mass spectrometry has always had a powerful synergy with computers. Computers have pushed mass spectrometry forward at key junctures in it’s history from data collection to instrument operation to data analysis.

From Bruker Life Sciences Mass Spectrometry 9 Sep 2020

Study illuminates the role of body temperature in realizing diet-induced health benefits

Cutting calories significantly may not be an easy task for most, but it's tied to a host of health benefits ranging from longer lifespan to a much lower chance of developing cancer, heart disease, diabetes and neurodegenerative conditions such as Alzheimer's.

8 Sep 2020

Mason researchers to provide biostatistics and bioinformatic analysis for new project

Virginia Espina, Research Associate Professor, Applied Proteomics and Molecular Medicine, received $21,000 from Baylor Research Institute for a project in which Mason researchers are providing biostatistics and bioinformatic analysis for integrating multi-omic data sets from a breast cancer cohort.

5 Sep 2020

Researchers identify biomarkers associated with bacterial infection mortality

David Gonzalez's "a-ha" moment came when a physician-colleague, George Sakoulas, MD, shared with him one of the biggest problems faced in clinical practice: How long it takes to diagnose a patient.

4 Sep 2020

Scientists identify robust set of biomarkers to help guide treatment for brain injuries

A scientific team led by the University of Arizona and the Translational Genomics Research Institute, an affiliate of City of Hope, identified a robust set of biomarkers through proteomics and metabolomic analysis that could help guide treatment for tens of millions of patients who each year sustain brain injuries, potentially preventing severe long-term disabilities.

3 Aug 2020