Metabolomics News and Research

Latest Metabolomics News and Research

Researchers identify new biomarker for severe COVID-19

During the pandemic, it has become increasingly evident that people with cardiovascular disease and obesity are at a much higher risk of developing very severe, even fatal COVID-19 disease.

8 Oct 2021

Metabolic and immune markers as tools for risk stratification and monitoring in COVID-19

In a new study posted to the medRxiv* server scientists from Weil Cornell University and Stony Brook University in New York attempted to identify the metabolic and immune markers associated with severe COVID-19 disease using high-throughput targeted nuclear magnetic resonance (NMR) spectroscopy and high-dimensional flow cytometry. This will facilitate risk stratification, monitoring, and therapeutic interventions in COVID-19 patients.

14 Sep 2021

Study finds accumulation of common therapeutic drugs by gut bacteria

Common medications can accumulate in gut bacteria, a new study has found, altering bacterial function and potentially reducing the effectiveness of the drug.

8 Sep 2021

Newly identified mechanism can accelerate the development of STING-activating drugs using imaging

A new study from scientists at the UCLA Jonsson Comprehensive Cancer Center found that emerging drugs that activate the protein STING, a well-established regulator of immune cell activation, substantially alter the activity of metabolic pathways responsible for generating the nucleotide building blocks for DNA.

7 Sep 2021

Research reveals a previously unknown role for a key transcription regulator linked to cancer

CTCF is a transcription factor that has been a research target due to its role in regulating a critical oncogene called MYC.

7 Sep 2021

Weill Cornell receives NIH support to advance TB research

Tuberculosis (TB) is one of the deadliest infectious diseases in history and one of the few that naturally infects only humans.

4 Sep 2021

New MOGONET outperforms existing supervised multi-omics integrative analysis approaches

Genomics, proteomics, metabolomics, transcriptomics -- rapid advances in high-throughput biomedical technologies has enabled the collection of data with unprecedented detail from the growing number of omics.

27 Aug 2021

Child with Bachmann-Bupp Syndrome successfully treated in just 16 months

Diagnosing a rare medical condition is difficult. Identifying a treatment for it can take years of trial and error. In a serendipitous intersection of research expertise, an ill patient in this case a child and innovative technology, Bachmann-Bupp Syndrome has gone from a list of symptoms to a successful treatment in just 16 months.

20 Jul 2021

Metabolomics: The Individual Metabolic Profile is the Key to Personalized Medicine

The study of these unique substances in each of us paves the way for a revolution in the treatment and prevention of diseases, allowing for early diagnosis and increasingly targeted pharmacological treatments.

From Bruker BioSpin - NMR, EPR and Imaging 14 Jul 2021

USF receives $69.9 Million NIH funding to continue study on type 1 diabetes

The National Institutes of Health has awarded the University of South Florida total expected funds of $69.9 million over the next four years to continue the follow-up of study participants in The Environmental Determinants of Diabetes in The Young (TEDDY) consortium.

13 Jul 2021

Untargeted metabolomics profiling can improve diagnosis of metabolic disorders in newborns

A team led by researchers at Baylor College of Medicine found that a screening method known as untargeted metabolomics profiling can improve the diagnostic rate for inborn errors of metabolism, a group of rare genetic conditions, by about seven-fold when compared to the traditional metabolic screening approach.

12 Jul 2021

Can saliva metabolomics predict COVID-19 severity?

New research suggests that saliva metabolomics may be able to help prognosticate disease severity in COVID-19 positive individuals.

9 Jul 2021

Biomarker discovery can open door to screening newborn babies for pyridoxine-dependent epilepsy

The door has finally opened on screening newborn babies for pyridoxine-dependent epilepsy (PDE), a severe inherited metabolic disorder. This screening promises to enable better and earlier treatment of the disease.

8 Jul 2021

A new method for generating metabolic profiles of single cells

Scientists from the European Molecular Biology Laboratory and the German Cancer Research Center have presented a new method for generating metabolic profiles of individual cells.

6 Jul 2021

Metabolomics lab analysis reveals large nutritional differences between near-meat and meat

Plant-based meat substitutes taste and chew remarkably similar to real beef, and the 13 items listed on their nutrition labels - vitamins, fats and protein -- make them seem essentially equivalent.

6 Jul 2021

Study provides a reliable early prognostic biomarker for COVID-19 severity

In a retrospective, multi-centre cohort study conducted by researchers from Nanjing University, Huazhong University of Science and Technology, Jinling Hospital and the Second Hospital of Nanjing, a microRNA-like small RNA encoded by SARS-CoV-2 was identified in the serum of COVID-19 patients, which can be developed as a non-invasive biomarker for stratification of severe patients from mild/moderate ones and for identification of high-risk individuals before clinical manifestation of severe symptoms.

6 Jul 2021

World-first study uses artificial intelligence to map the risks of ovarian cancer in women

The University of South Australia will lead a world-first study, using artificial intelligence, to map the risks of the most fatal reproductive cancer in women worldwide so it can be detected and treated earlier.

2 Jul 2021

Genetic variants in a neuro-associated gene cause neurodevelopmental disorder, finds study

Mayo Clinic researchers have discovered that genetic variants in a neuro-associated gene called SPTBN1 are responsible for causing a neurodevelopmental disorder. The study, published in Nature Genetics, is a first step in finding a potential therapeutic strategy for this disorder, and it increases the number of genes known to be associated with conditions that affect how the brain functions.

2 Jul 2021

New biomarkers can predict HIV remission after antiretroviral therapy interruption

New biomarkers that predict HIV remission after antiretroviral therapy (ART) interruption are critical for the development of new therapeutic strategies that can achieve infection control without ART, a condition defined as functional cure.

29 Jun 2021

Nicotinamide can help stimulate plant immune systems, shows study

Fungal diseases in cereal crops cause major economic losses and also threaten human and livestock health, because some fungi produce powerful toxins that might enter the food chain. Farmers use fungicides to control crop diseases, such as wheat head blight. Although agrochemicals are rigorously tested for safety, there can be concerns over chemical residues in food.

11 Jun 2021

Metabolomics News and Research

Latest Metabolomics News and Research

Researchers identify new biomarker for severe COVID-19

Metabolic and immune markers as tools for risk stratification and monitoring in COVID-19

Study finds accumulation of common therapeutic drugs by gut bacteria

Newly identified mechanism can accelerate the development of STING-activating drugs using imaging

Research reveals a previously unknown role for a key transcription regulator linked to cancer

Weill Cornell receives NIH support to advance TB research

New MOGONET outperforms existing supervised multi-omics integrative analysis approaches

Child with Bachmann-Bupp Syndrome successfully treated in just 16 months

Metabolomics: The Individual Metabolic Profile is the Key to Personalized Medicine

USF receives $69.9 Million NIH funding to continue study on type 1 diabetes

Untargeted metabolomics profiling can improve diagnosis of metabolic disorders in newborns

Can saliva metabolomics predict COVID-19 severity?

Biomarker discovery can open door to screening newborn babies for pyridoxine-dependent epilepsy

A new method for generating metabolic profiles of single cells

Metabolomics lab analysis reveals large nutritional differences between near-meat and meat

Study provides a reliable early prognostic biomarker for COVID-19 severity

World-first study uses artificial intelligence to map the risks of ovarian cancer in women

Genetic variants in a neuro-associated gene cause neurodevelopmental disorder, finds study

New biomarkers can predict HIV remission after antiretroviral therapy interruption

Nicotinamide can help stimulate plant immune systems, shows study

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