Neuroblastoma News and Research

Latest Neuroblastoma News and Research

Researchers uncover new and unexploited drug target for childhood cancer

An Australian-led international research effort has broken fresh ground in the race to find more effective treatments for the childhood cancer neuroblastoma, by uncovering a new and as-yet unexploited target in cancer cells that therapeutic drugs can be aimed at.

12 Nov 2019

Preclinical data on new drug combination to treat neuroblastoma published

Neuroblastoma is the most common cancer outside of the brain in infants and young children and often fails to respond to therapy. Though it can appear in several areas of the body, it commonly develops as a solid tumor most frequently found in or adjacent to the adrenal glands, which sit atop the kidneys.

10 Nov 2019

St. Jude Children's Research Hospital and IAEA team up to combat childhood cancers

The International Atomic Energy Agency and St. Jude Children's Research Hospital are joining forces to combat childhood cancers in developing countries, where children are four times more likely to die of the disease than in high-income countries due to a lack of affordable treatment and quality care options.

18 Oct 2019

Researchers identify targeted therapy for adolescent patients with neuroblastoma

Mount Sinai researchers have identified a targeted therapy for adolescent patients with neuroblastoma, a deadly pediatric nerve cancer, who would otherwise have no treatment options, according to a study published in October in Cancer Cell.

17 Oct 2019

New algorithm can help reduce therapy for some patients with intermediate-risk neuroblastoma

A recent Children's Oncology Group study identified a treatment algorithm that can help reduce therapy for some neuroblastoma patients with intermediate-risk disease, while maintaining good clinical outcomes.

2 Oct 2019

Ruthenium probes shed new light on cause of Alzheimer's disease

Rice University researchers have found a way to track the formation of soluble amyloid beta peptide aggregates implicated in the onset of Alzheimer's disease.

23 Sep 2019

Removing tumor's protective wall could help boost the effects of cancer treatments

Scientists may have found a way to pull down the protective wall that surrounds tumors, potentially re-exposing them to the killing power of the immune system and immunotherapy treatments, according to a study part funded by Cancer Research UK and published in EBioMedicine today (Monday).

26 Aug 2019

Study aims to reduce therapy for subsets of patients with intermediate-risk neuroblastoma

Each year, approximately 750 patients are diagnosed with neuroblastoma in North America, the most common form of cancer in infants less than one year old.

8 Aug 2019

Australian researchers discover gene that plays key role in aggressive childhood cancer

Neuroblastoma accounts for 15% of total childhood cancer deaths. The survival rate of high-risk neuroblastoma patients is 50%.

27 Jul 2019

Children with birth defects have elevated cancer risk, study reveals

Childhood cancer is a rare occurrence in the overall population but may be somewhat more frequent in children born with birth defects.

26 Jun 2019

Study aims at developing new therapies to fight childhood cancer

Researchers from the Department of Cellular Biology at the University of Seville and the Seville Institute of Biomedicine, Pablo Vicente and Doctor Luisma Escudero, in close collaboration with the researcher Rebecca Burgos and other members of the group of Doctor Rosa Noguera have published a study aimed at developing new therapies to fight childhood cancer.

12 Jun 2019

IU researchers, collaborators receive grant to develop immunotherapy treatments for cancer

A team of researchers from Indiana University and Memorial Sloan Kettering Cancer Center have been awarded a $4.1 million National Cancer Institute "Cancer Moonshot" grant to develop immunotherapy treatments for cancer in children and adolescents, especially those with leukemia.

31 May 2019

Researchers develop synthetic molecules that deliver drugs to neuroblastoma

Researchers from Universidad Politécnica de Madrid are involved in the development of specific molecular scaffolds which are able to deliver drugs and diagnostic agents to the neuroblastoma, an aggressive tumor in children.

27 May 2019

Potential new therapeutic approach identified for neuroblastoma tumors

Research led by Michael Lan, PhD, Professor of Pediatrics and Genetics at LSU Health New Orleans School of Medicine, found that a compound named 5'-iodotubercidin (5'-IT) suppresses the growth of neuroblastoma cells and identified a potential new therapeutic approach for the disease.

12 Apr 2019

Study describes vulnerability shared by large subset of cancer cell lines

Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in the process becoming dependent on those genes for their survival and growth.

12 Apr 2019

Proton therapy shows excellent outcomes, minimal side effects in high-risk neuroblastoma patients

Researchers from Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania analyzed the largest cohort to date of pediatric patients with high-risk neuroblastoma treated with proton radiation therapy, finding both that proton therapy was effective at reducing tumors and demonstrated minimal toxicity to surrounding organs.

10 Apr 2019

Antibody-drug conjugate effectively targets surface protein in childhood neuroblastomas

Physician-scientists in the Cancer Center at Children's Hospital of Philadelphia have developed a preclinical, potent therapy attached to an antibody that targets a surface protein expressed in most childhood neuroblastomas, effectively killing cancer cells.

14 Mar 2019

Causes of disease including infant cancer can be revealed with new tool from Princeton University research team

Machine learning is being used to gain insight into the causes of hundreds of diseases, with Princeton University researchers discovering four specific genes that contribute to infant cancer.

4 Mar 2019

New tool uncovers molecular causes of different diseases

Princeton University researchers are gaining new insights into the causes and characteristics of diseases by harnessing machine learning to analyze molecular patterns across hundreds of diseases simultaneously.

1 Mar 2019

Johns Hopkins researchers find genetic cause of olfactory neuroblastoma

By sequencing the entire genomes of tumor cells from six people with a rare cancer of the nose and sinus cavity, Johns Hopkins researchers report they unexpectedly found the same genetic change¾one in a gene involved in muscle formation¾in five of the tumors.

28 Feb 2019

Neuroblastoma News and Research

Latest Neuroblastoma News and Research

Researchers uncover new and unexploited drug target for childhood cancer

Preclinical data on new drug combination to treat neuroblastoma published

St. Jude Children's Research Hospital and IAEA team up to combat childhood cancers

Researchers identify targeted therapy for adolescent patients with neuroblastoma

New algorithm can help reduce therapy for some patients with intermediate-risk neuroblastoma

Ruthenium probes shed new light on cause of Alzheimer's disease

Removing tumor's protective wall could help boost the effects of cancer treatments

Study aims to reduce therapy for subsets of patients with intermediate-risk neuroblastoma

Australian researchers discover gene that plays key role in aggressive childhood cancer

Children with birth defects have elevated cancer risk, study reveals

Study aims at developing new therapies to fight childhood cancer

IU researchers, collaborators receive grant to develop immunotherapy treatments for cancer

Researchers develop synthetic molecules that deliver drugs to neuroblastoma

Potential new therapeutic approach identified for neuroblastoma tumors

Study describes vulnerability shared by large subset of cancer cell lines

Proton therapy shows excellent outcomes, minimal side effects in high-risk neuroblastoma patients

Antibody-drug conjugate effectively targets surface protein in childhood neuroblastomas

Causes of disease including infant cancer can be revealed with new tool from Princeton University research team

New tool uncovers molecular causes of different diseases

Johns Hopkins researchers find genetic cause of olfactory neuroblastoma

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Neuroblastoma News and Research

Latest Neuroblastoma News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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