Pharmacology News and Research

Latest Pharmacology News and Research

Combination of anti-nausea drug and turmeric spice target cancer cells

In a laboratory, preclinical study recently published by the journal Organic & Biomolecular Chemistry, Virginia Commonwealth University Massey Cancer Center researchers combined structural features from anti-nausea drug thalidomide with common kitchen spice turmeric to create hybrid molecules that effectively kill multiple myeloma cells.

20 Aug 2013

Researchers identify key transcription factor linked with treatment-resistant prostate cancer

Prostate cancer is one of the most common forms of cancer in men and the leading cause of cancer deaths in white, African-American and Hispanic men, according to the Centers for Disease Control. Current treatment of prostate cancer targets androgens, hormones which promote the growth and spread of cancer cells.

20 Aug 2013

Newly expanded role for pharmacists helps manage health of patients

The newly expanded role that pharmacists in Canada now have in helping manage the health of patients can benefit both patients and physicians, according to an article in CMAJ (Canadian Medical Association Journal).

20 Aug 2013

Basic cancer research at Creighton yields promising results for diagnosing, treating asthma

What started as basic cancer research at Creighton University has yielded promising results for diagnosing and treating asthma - and the National Institutes of Health (NIH) agrees, investing nearly $1.5 million in Creighton to find out more.

17 Aug 2013

Study suggests Braintone has neuroprotective effects on ischemia-induced brain damage

Recently, the importance of the neurovascular unit, which is comprised of neurons, endothelial cells and astrocytes, has received great attention in the field of stroke, because stroke affects not only neurons, but also astrocytes and microvessels.

17 Aug 2013

Pre-doctoral students receive International Student Research Fellowships from HHMI

The Howard Hughes Medical Institute has awarded two doctoral students from the Sackler School of Graduate Biomedical Sciences at Tufts University with 2013 International Student Research Fellowships. Seblewongel Asrat, from Ethiopia, studies the bacterium that causes Legionnaires' disease while Jennifer Nwankwo, from Nigeria, studies red blood cell dehydration in sickle cell disease.

17 Aug 2013

Scientists develop new therapies to prevent chemoresistance of established tumours

Cancer cells often develop defence mechanisms which enable them to survive chemotherapy. A group of researchers from the Institutes of Pharmacology and Pathology in Bern present new solutions for preventing the development of such resistances.

17 Aug 2013

Omega-3 rich oils improve membrane fluidity in retina cells and help fight age-related eye diseases

Scientists working at the Research Center on Aging at the Health and Social Services Centre - University Institute of Geriatrics of Sherbrooke (CSSS-IUGS) have been studying strategies for protecting retinal pigment epithelium (RPE) cells.

16 Aug 2013

Novel neural mechanism may help improve therapies for spinal injuries, neurodegenerative diseases

University of Arizona scientists have discovered an unknown mechanism that establishes polarity in developing nerve cells. Understanding how nerve cells make connections is an important step in developing cures for nerve damage resulting from spinal cord injuries or neurodegenerative diseases such as Alzheimer's.

16 Aug 2013

Gene variant linked with Mediterranean diet pattern prevents stroke

A gene variant strongly associated with development of type 2 diabetes appears to interact with a Mediterranean diet pattern to prevent stroke, report researchers from the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University and from the CIBER Fisiopatolog-a de la Obesidad y Nutriciόn in Spain.

14 Aug 2013

Study reveals cancer in humans linked with high amounts of proteins responsible for cells division

Cancer in humans is frequently associated with unusually high amounts of one or more proteins responsible for controlling the rate at which cells divide. As an example, excessive amounts of the cyclin-dependent kinase CDK6 are often found in types of cancer such as lymphoma.

14 Aug 2013

X-linked methyl-CpG protein may be potential target for treatment of Parkinson's

X-linked methyl-CpG binding protein 2 plays important role in the regulation of neuronal development, proliferation and maturation, and synaptic regeneration and apoptosis.

13 Aug 2013

NCI renews UCLA prostate SPORE grant

UCLA's Jonsson Comprehensive Cancer Center and the department of urology at the David Geffen School of Medicine at UCLA have been notified that their standing as a National Cancer Institute Specialized Program of Research Excellence site in prostate cancer has been renewed for another five years.

8 Aug 2013

ASH to award 2013 William Dameshek Prize to Andrew S. Weyrich

The American Society of Hematology will present the 2013 William Dameshek Prize to Andrew S. Weyrich, PhD, of The University of Utah for his seminal research on the cellular and molecular causes of blood clots.

2 Aug 2013

FDA grants orphan-drug designation to Convergence's CNV1014802 for treatment of TN

Convergence Pharmaceuticals Limited, the company focused on the development of novel and high value analgesic medicines for the treatment of chronic pain, is pleased to announce that its novel sodium channel blocker, CNV1014802 ('802), has been granted orphan-drug designation by the US Food and Drug Administration for the treatment of trigeminal neuralgia.

30 Jul 2013

FDA grants orphan-drug designation for Ligand’s Captisol-enabled Topiramate Injection

Ligand Pharmaceuticals Incorporated announced that the U.S. Food and Drug Administration (FDA) has granted orphan-drug designation for its proprietary Captisol-enabled Topiramate Injection for the treatment of partial onset or primary generalized tonic-clonic seizures in hospitalized epilepsy patients who are unable to take oral topiramate.

26 Jul 2013

Non-invasive optical techniques use LED, laser to view beneath skin

Impressive examples of new non-invasive optical techniques using lasers, light-emitting diodes (LEDs), and spectroscopic methods to probe and render images from beneath the surface of the skin are featured in a newly completed special section in the Journal of Biomedical Optics published by SPIE, the international society for optics and photonics.

26 Jul 2013

Researchers explain how gut bacteria can inactivate cardiac drugs

For decades, doctors have understood that microbes in the human gut can influence how certain drugs work in the body - by either activating or inactivating specific compounds, but questions have long remained about exactly how the process works.

26 Jul 2013

Study: Daily dietary supplementation with blend of omega fatty acids improves severe dry eye

Study findings published online, ahead of print, in Cornea show that daily dietary supplementation with a unique combination of omega fatty acids (GLA, EPA and DHA) for six months is effective in improving ocular irritation symptoms and halting the progression of inflammation that characterizes moderate to severe dry eye.

25 Jul 2013

Forced-air patient warming systems may affect airflows in OR; increase exposure to airborne contaminants

Forced-air systems used to keep patients warm during surgery may affect the performance of operating room (OR) ventilation systems-potentially increasing exposure to airborne contaminants, reports a study in the August issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

25 Jul 2013

Pharmacology News and Research

Latest Pharmacology News and Research

Combination of anti-nausea drug and turmeric spice target cancer cells

Researchers identify key transcription factor linked with treatment-resistant prostate cancer

Newly expanded role for pharmacists helps manage health of patients

Basic cancer research at Creighton yields promising results for diagnosing, treating asthma

Study suggests Braintone has neuroprotective effects on ischemia-induced brain damage

Pre-doctoral students receive International Student Research Fellowships from HHMI

Scientists develop new therapies to prevent chemoresistance of established tumours

Omega-3 rich oils improve membrane fluidity in retina cells and help fight age-related eye diseases

Novel neural mechanism may help improve therapies for spinal injuries, neurodegenerative diseases

Gene variant linked with Mediterranean diet pattern prevents stroke

Study reveals cancer in humans linked with high amounts of proteins responsible for cells division

X-linked methyl-CpG protein may be potential target for treatment of Parkinson's

NCI renews UCLA prostate SPORE grant

ASH to award 2013 William Dameshek Prize to Andrew S. Weyrich

FDA grants orphan-drug designation to Convergence's CNV1014802 for treatment of TN

FDA grants orphan-drug designation for Ligand’s Captisol-enabled Topiramate Injection

Non-invasive optical techniques use LED, laser to view beneath skin

Researchers explain how gut bacteria can inactivate cardiac drugs

Study: Daily dietary supplementation with blend of omega fatty acids improves severe dry eye

Forced-air patient warming systems may affect airflows in OR; increase exposure to airborne contaminants

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