Pharmacology News and Research

Latest Pharmacology News and Research

Nearly 1/2 of older adults undergoing surgery with general anesthesia have delirium in PACU

Close to half of older adults undergoing surgery with general anesthesia are found to have delirium in the postanesthesia care unit (PACU), according to a study in the August issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

25 Jul 2013

Scientists identify new genetic mutations that can cause pulmonary arterial hypertension

Columbia University Medical Center (CUMC) scientists have identified new genetic mutations that can cause pulmonary arterial hypertension (PAH), a rare fatal disease characterized by high blood pressure in the lungs.

25 Jul 2013

Researchers suggest new key to switch off signaling pathways that lead to hypertension

A team of University of California, San Diego researchers has designed new compounds that mimic those naturally used by the body to regulate blood pressure. The most promising of them may literally be the key to controlling hypertension, switching off the signaling pathways that lead to the deadly condition.

23 Jul 2013

EU-funded project examines dietary habits in people with inadequate nutrition

Until now, we have had very little understanding of the extent of malnutrition in Europe, especially in populations at risk of poverty. Now, an EU-funded project calledCHANCE, aims to address the dietary habits in people with inadequate nutrition.

20 Jul 2013

Study leads to new approach for treatment of aortic valve stenosis

A study conducted by the team of Dr. Jean-Claude Tardif, Director of the Research Centre at the Montreal Heart Institute, has led to the discovery of a new approach to treat aortic valve stenosis through the administration of a compound that prevents valve deterioration and can even reverse the progression of the disease.

19 Jul 2013

Children exposed to AEDs in womb at risk of early development issues: Study

Children whose mothers took antiepileptic drugs while pregnant are at increased risk of early development issues, according to a new study published in Epilepsia, a journal published by Wiley on behalf of the International League Against Epilepsy.

18 Jul 2013

Novel way to fine-tune activity of cells' protein-disposing machinery with cancer-fighting effects

Molecular biologists in the School of Medicine at The University of Texas Health Science Center San Antonio have found a novel way to fine-tune the activity of cells' protein-disposing machinery, with potentially cancer-fighting effects.

18 Jul 2013

Drug that spurs cancer cells to self-destruct is on road to human clinical trials

Thanks to a new $2 million investment, a drug that spurs cancer cells to self-destruct while sparing healthy cells is on the road to human clinical trials. The compound, known as PAC-1, has so far proven safe and has promising anti-cancer effects in cell culture, in mouse models of cancer and in pet dogs with spontaneously occurring lymphomas and osteosarcomas.

18 Jul 2013

Long-term cannabis use, dopamine and motivation: an interview with Dr Michael Bloomfield, Department of Medicine at Imperial

We classified ‘long-term’ cannabis use as being regular, at least weekly, cannabis use for over 12 months. This is the period of time that’s used in the DSM-IV psychiatric diagnostic manual to classify substance use disorders. In our study the average duration of at least weekly use was just over four and a half years.

17 Jul 2013

The more you chew, the more energy you retain

Almonds may still be considered one of the highest energy food sources but it's not about how much you bite off, instead it's about how much you chew, according to a July 14 panel discussion at the 2013 Institute of Food Technologists Annual Meeting & Food Expo- held at McCormick Place.

17 Jul 2013

Largest data set of cancer-specific genetic variations generated by NCI scientists

Scientists at the National Cancer Institute have generated a data set of cancer-specific genetic variations and are making these data available to the research community, according to a study published in Cancer Research, a journal of the American Association for Cancer Research.

16 Jul 2013

USC study shows missing brain protein may be responsible for severe over-worry and fear

A little bit of learned fear is a good thing, keeping us from making risky, stupid decisions or falling over and over again into the same trap. But new research from neuroscientists and molecular biologists at USC shows that a missing brain protein may be the culprit in cases of severe over-worry, where the fear perseveres even when there's nothing of which to be afraid.

16 Jul 2013

Protein complex may be an effective alternative to opioid pain medications

A drug targeting a protein complex containing two different types of opioid receptors may be an effective alternative to morphine and other opioid pain medications, without any of the side effects or risk of dependence, according to research led by the Icahn School of Medicine at Mount Sinai.

16 Jul 2013

Assurex Health announces release of new psychiatric pharmacogenomic test panel

Assurex Health today announced the release of GeneSight Psychotropic 2.0, its lead psychiatric pharmacogenomic test panel. This latest GeneSight Psychotropic version has been updated to include four additional medications that now cover a total of 36 of the most commonly prescribed psychotropic medications in the US.

15 Jul 2013

Researchers find new potential treatment for cancer

A University of Southampton Professor, in collaboration with colleagues at the BC Cancer Agency Research Centre, have discovered a novel way of killing cancer cells. The research, recently published in the journal Cell, has found a new potential treatment for cancer, which leaves the body's healthy cells undamaged, unlike traditional therapies such as radiotherapy.

12 Jul 2013

Scientists set out to develop safer versions of acetaminophen

Efforts to develop a safer form of acetaminophen - the pain and fever-reducer that is one of the most widely used drugs - have led to discovery of substances that may have less potentially toxic effects on the liver. A report on the research appears in ACS Medicinal Chemistry Letters.

12 Jul 2013

UNMC conducts clinical trial on Leukine to test unique immune therapy in people with Parkinson's

The Nebraska Neuroscience Alliance at the University of Nebraska Medical Center, is embarking on a translational clinical trial using Leukine, a drug used to boost the immune system in cancer patients, to test a unique immune therapy in people with Parkinson's disease.

11 Jul 2013

Resurgence in cardiovascular R&D is urgently needed to curb new epidemic of CVD

A resurgence in cardiovascular R&D is urgently needed to curb a new epidemic of cardiovascular diseases, according to leading cardiologists and industry representatives in the Cardiovascular Round Table (CRT).

10 Jul 2013

Research finding may offer novel path for cancer drug design

Genetic mutations aren't the only thing that can keep a protein called PTEN from doing its tumor-suppressing job. Johns Hopkins researchers have now discovered that four small chemical tags attached (reversibly) to the protein's tail can have the same effect, and they say their finding may offer a novel path for drug design to keep PTEN working.

10 Jul 2013

p53 restoration of function drug candidate: an interview with Dr. Wayne Danter, MD, FRCPC President and CEO of Critical Outcome Technologies

COTI-2 is a computer-designed small molecule that was discovered by our artificial intelligence drug discovery platform called CHEMSAS.

8 Jul 2013

Pharmacology News and Research

Latest Pharmacology News and Research

Nearly 1/2 of older adults undergoing surgery with general anesthesia have delirium in PACU

Scientists identify new genetic mutations that can cause pulmonary arterial hypertension

Researchers suggest new key to switch off signaling pathways that lead to hypertension

EU-funded project examines dietary habits in people with inadequate nutrition

Study leads to new approach for treatment of aortic valve stenosis

Children exposed to AEDs in womb at risk of early development issues: Study

Novel way to fine-tune activity of cells' protein-disposing machinery with cancer-fighting effects

Drug that spurs cancer cells to self-destruct is on road to human clinical trials

Long-term cannabis use, dopamine and motivation: an interview with Dr Michael Bloomfield, Department of Medicine at Imperial

The more you chew, the more energy you retain

Largest data set of cancer-specific genetic variations generated by NCI scientists

USC study shows missing brain protein may be responsible for severe over-worry and fear

Protein complex may be an effective alternative to opioid pain medications

Assurex Health announces release of new psychiatric pharmacogenomic test panel

Researchers find new potential treatment for cancer

Scientists set out to develop safer versions of acetaminophen

UNMC conducts clinical trial on Leukine to test unique immune therapy in people with Parkinson's

Resurgence in cardiovascular R&D is urgently needed to curb new epidemic of CVD

Research finding may offer novel path for cancer drug design

p53 restoration of function drug candidate: an interview with Dr. Wayne Danter, MD, FRCPC President and CEO of Critical Outcome Technologies

Industry Focus - Biopharma eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Pharmacology News and Research

Latest Pharmacology News and Research

Industry Focus - Biopharma eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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