Pharmacology News and Research

Latest Pharmacology News and Research

Review: Mercury likely plays role in development of AD

Mercury likely plays a role in the development of Alzheimer's disease, according to a review of relevant scientific literature published this month in The Journal of Alzheimer's Disease. Dr. Joachim Mutter of Germany, Dr. Richard Deth of the United States, and other esteemed researchers collaborated on the groundbreaking article Does Inorganic Mercury Play a Role in Alzheimer's Disease? A Systematic Review and an Integrated Molecular Mechanism, which clarifies the need for continuing research to understand the cause of neurological diseases such as Alzheimer's.

16 Nov 2010

New i-phone application provides instant access to HIV drug interactions

The University of Liverpool has launched an i-phone application, HIV iChart,that provides healthcare professionals and HIV patients with instant and easy access to information about drug interactions.

16 Nov 2010

PAREXEL wins 2010 Scrip Award for 'Clinical Research Team of the Year'

PAREXEL International Corporation, a leading global biopharmaceutical services provider, today announced that the Company has won the 2010 Scrip Award for "Clinical Research Team of the Year." The award was presented to PAREXEL at the sixth annual Scrip Awards ceremony, hosted by Scrip Intelligence, a leading news, data, and information service for the global pharmaceutical industry, on November 4, 2010 in London, England.

From Parexel 15 Nov 2010

Acne, acne medicine and mental health: Study

Acne drug Accutane (isotretinoin) has been plagued by serious controversies with some linking it to suicidal tendencies. Now the latest research finds that severe acne itself increases the risk for suicidal thoughts and actions, raising more questions about the role of the drug, if any, in suicide.

14 Nov 2010

Amorfix second quarter net loss decreases to $25,728

Amorfix Life Sciences, a product development company focused on the development of diagnostics and therapeutics for misfolded protein diseases, today announced its operational and financial results for the three and six months ended September 30, 2010.

12 Nov 2010

New findings suggest serotonin may have anti-diabetic property

New findings by researchers at UT Southwestern Medical Center suggest that serotonin a brain chemical known to help regulate emotion, mood and sleep might also have anti-diabetic properties.

11 Nov 2010

MqsA and MqsR protein complex can disrupt drug-resistant biofilm formation

When a foreign object such as a catheter enters the body, bacteria may not only invade it but also organize into a slick coating - a biofilm - that is highly resistant to antibiotics. Like sophisticated organized crime rings, biofilms cannot be defeated by a basic approach of conventional means. Instead doctors and drug developers need sophisticated new intelligence that reveals the key players in the network and how they operate. New research led by biologists at Brown University provides exactly that dossier on some key proteins in the iconic bacterium E. coli.

11 Nov 2010

Evotec revenues increase 33% to € 38.8 m during first nine months of 2010

Evotec AG today reported financial results and a corporate update for the first nine months of 2010.

11 Nov 2010

Alnylam Pharmaceuticals presents ALN-VSP Phase I data for liver cancer at Chemotherapy Foundation Symposium

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, today presented additional interim data from its ongoing Phase I trial with ALN-VSP, a systemically delivered RNAi therapeutic for the treatment of advanced solid tumors with liver involvement. The data were presented at the Chemotherapy Foundation Symposium being held in New York City.

11 Nov 2010

Childhood asthma risk linked with prenatal paracetamol exposure depends on antioxidant genes in mother

Evidence suggesting that the risk of childhood asthma associated with prenatal paracetamol exposure may depend on antioxidant genes in the mother has been found by a team of UK scientists. The results of their study - which strengthens the argument for a causal link between paracetamol exposure in early life and later childhood asthma - are published online (10 November) in the Journal of Allergy and Clinical Immunology.

11 Nov 2010

Chocolates inhibit enzyme known to raise blood pressure

Numerous studies have shown that cocoa has a protective effect against cardiovascular diseases. The reason for this has now been uncovered by researchers at Linköping University in Sweden. When a group of volunteers devoured a good-sized piece of dark chocolate, it inhibited an enzyme in their bodies that is known to raise blood pressure.

10 Nov 2010

New TB-drugome may help identify protein targets for tuberculosis

Researchers at the University of California, San Diego School of Medicine and the University of Leeds have linked hundreds of federally approved drugs to more than 1,000 proteins in Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), opening new avenues to repurpose these drugs to treat TB.

9 Nov 2010

EpiCept third quarter net loss decreases to $3.2 million

EpiCept Corporation today announced operating and financial results for the three and nine months ended September 30, 2010, and provided an update with respect to the Company's key business initiatives.

9 Nov 2010

Positive results from Ardea's RDEA594 combination study with febuxostat or allopurinol for gout

Ardea Biosciences, Inc. announced positive results from two clinical studies of RDEA594 in combination with currently marketed drugs for the treatment of gout patients, febuxostat (Uloric®) and allopurinol.

8 Nov 2010

Research findings on RGL2 protein can lead to new therapeutic target for pancreatic cancer

One of the most frustrating problems faced by doctors who treat pancreatic cancer is the lack of effective therapeutic options. More than 38,000 people in the United States die of the disease each year, and new drugs and treatments are desperately needed.

8 Nov 2010

TRPM7 protein plays a key role in maintenance of magnesium homeostasis

An international team led by researchers at the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School has published new findings that demonstrate how a specific protein controls the body's ability to balance magnesium levels. Magnesium is an essential element for good health and is critical to more than 300 biochemical reactions that occur in the body.

8 Nov 2010

Alder to present data of ALD518 two clinical studies for rheumatoid arthritis at American College Meeting

Alder Biopharmaceuticals Inc. today announced that data from two clinical studies of its ALD518 investigational antibody therapeutic will be presented at the Annual Meeting of the American College of Rheumatology in Atlanta.

8 Nov 2010

New noninvasive technique to detect methemoglobin level

Potentially harmful levels of methemoglobin which can build up in patients receiving certain anesthetics are detectable using a new, noninvasive monitoring technique called pulse CO-oximetry, reports a study in the November issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

4 Nov 2010

New noninvasive technique provides low-level electrical stimulation to reduce pain

A simple, noninvasive technique providing low-level electrical stimulation of the brain produces significant pain-reducing effects in humans, reports the November issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

4 Nov 2010

OMJPI enters agreement with Watson to distribute generic version of CONCERTA tablets

Ortho-McNeil-Janssen Pharmaceuticals, Inc. today announced it has entered into a supply and distribution agreement with Watson Laboratories, Inc. to distribute an authorized generic version of CONCERTA (methylphenidate HCl extended-release tablets).

3 Nov 2010