Pharmacology News and Research

Latest Pharmacology News and Research

$Worldwide hip fracture counts likely to double by 2050, study finds$

Worldwide hip fracture counts likely to double by 2050, study finds

Osteoporotic hip fracture, already a dangerous and debilitating problem for older men and women worldwide, is poised to become a far more severe global public-health issue as the population grows older and frailer, according to a new study led by researchers at the University of Hong Kong.

12 Sep 2022

Phase III ADAURA trial reveals promising results for patients with non-small cell lung cancer

Newly released results from the Phase III ADAURA trial reveal that osimertinib yielded a 5.5-year median disease-free survival in the post-surgical treatment of patients with EGFR-mutated lung cancer, and nearly three in four patients treated with adjuvant osimertinib were disease-free at four years.

12 Sep 2022

Study shortlists potential drug repurposing candidates to treat symptoms in ASD

Can you teach an old drug new tricks? Although drug treatments for the core symptoms of autism spectrum disorder (ASD) are not currently available, could an existing drug provide a new treatment, even if it previously had no association with ASD? This was the question asked by a new study in the journal Frontiers in Pharmacology. The researchers used a computer model that encompasses proteins involved in ASD and the way they interact.

12 Sep 2022

Tumor-infiltrating lymphocytes therapy treats cancers at a large scale

A novel treatment strategy with personalized cell therapy significantly improves progression-free survival compared to standard immunotherapy in patients with advanced melanoma, according to ground-breaking results reported at the ESMO Congress 2022 from the phase 3 M14TIL trial.

12 Sep 2022

HKUMed team estimates a moderate link between antipsychotic use and breast cancer by over 30%

A research team from the Centre for Safe Medication Practice and Research (CSMPR), Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) conducted the world's first systematic review and meta-analysis of observational studies with over two million individuals and estimated a moderate association between antipsychotic use and breast cancer by over 30%.

9 Sep 2022

Licorice compounds proposed as effective candidates for treatment of COVID-19

Researchers describe the different mechanisms by which licorice active ingredients target SARS-CoV-2.

8 Sep 2022

Promising anti-cancer agent may also prevent SARS-CoV-2 from replication

Based on findings from a new study by a Johns Hopkins Medicine-led research team, an effective means of fighting SARS-CoV-2, the virus that causes COVID-19, may be possible that circumvents the problem of waning immunity often observed when current vaccines deal with emerging COVID variants.

8 Sep 2022

Study establishes link between Piezo1 and intracellular cholesterol levels during neural development

A new University of California, Irvine-led study reveals how mechanical forces and tissue mechanics influence the morphology of the developing brain, and establishes a direct link in neural stem cells between Piezo1, a mechanically-activated ion channel, and intracellular cholesterol levels during neural development.

8 Sep 2022

Total lockdown during COVID-19 has measurable impact on vascular health, research shows

A new paper in European Heart Journal - Digital Health, published by Oxford University Press, indicates that social-distancing measures like total lockdown have a measurable impact on vascular health.

6 Sep 2022

Lactate may have a previously unrecognized role in fighting cancer

A new study by UT Southwestern's Simmons Cancer Center scientists suggests that lactate, a metabolic byproduct produced by cells during strenuous exercise, can rejuvenate immune cells that fight cancer.

6 Sep 2022

Trial compares two different lung volume reduction procedures for people with emphysema

The first randomized controlled trial to compare two different lung volume reduction procedures for people with emphysema has found that both lead to similar improvements in lung function, breathlessness and exercise capacity.

5 Sep 2022

Researchers secure $20.5 million NIH grant to beat Alzheimer's disease and related dementias

A team of researchers at the University of Kentucky's Sanders-Brown Center on Aging has been awarded a $20.5 million grant from the National Institute on Aging of the National Institutes of Health.

2 Sep 2022

Leukemia drug successfully disrupts HER2-positive brain metastasis in animal studies

In animal studies led by researchers at Duke Cancer Institute, a drug approved to treat leukemia successfully disrupted the ability of HER2-positive breast cancer tumors from colonizing the brain.

30 Aug 2022

Vitamin D mediates crosstalk between COVID-19 and osteoporosis

Researchers identify and characterize the targets of Vit D on COVID-19 and osteoporosis.

30 Aug 2022

Penn State receives $1.6 million grant to study the link between COVID-19 and cognitive decline

As populations around the globe age, dementia -; often caused by Alzheimer's disease and related disorders -; is a growing health issue for older adults worldwide.

26 Aug 2022

Researchers develop a protein thermal shift chip for COVID-19

Announcing a new publication for Acta Materia Medica journal. Traditional protein chips are based on solid chips and cannot enable drug and target screening in a label-free manner.

26 Aug 2022

Penn-CHOP Kidney Innovation Center focuses on early detection, prevention, and treatment of kidney disease

In an effort to improve the lives of children and adults with kidney disease, Children's Hospital of Philadelphia and Penn Medicine are jointly launching the Penn-CHOP Kidney Innovation Center.

26 Aug 2022

Researchers report large molecular compounds and nanoscale nanozyme of two traditional Chinese medicines may inhibit COVID-19 signaling

Researchers investigated the potential anti-COVID-19 activity of traditional Chinese medicine.

25 Aug 2022

Scientists demonstrate safety of neurosurgical procedure used to measure dopamine and serotonin

Scientists at Wake Forest University School of Medicine have demonstrated that a neurosurgical procedure used to research and measure dopamine and serotonin in the human brain is safe.

24 Aug 2022

Simple computer program may help personalize cancer treatment

Cancer Council SA-funded researcher Associate Professor Stephanie Reuter Lange from UniSA hopes that a simple computer program can help personalize treatment for cancer patients.

23 Aug 2022

Pharmacology News and Research

Latest Pharmacology News and Research

Worldwide hip fracture counts likely to double by 2050, study finds

Phase III ADAURA trial reveals promising results for patients with non-small cell lung cancer

Study shortlists potential drug repurposing candidates to treat symptoms in ASD

Tumor-infiltrating lymphocytes therapy treats cancers at a large scale

HKUMed team estimates a moderate link between antipsychotic use and breast cancer by over 30%

Licorice compounds proposed as effective candidates for treatment of COVID-19

Promising anti-cancer agent may also prevent SARS-CoV-2 from replication

Study establishes link between Piezo1 and intracellular cholesterol levels during neural development

Total lockdown during COVID-19 has measurable impact on vascular health, research shows

Lactate may have a previously unrecognized role in fighting cancer

Trial compares two different lung volume reduction procedures for people with emphysema

Researchers secure $20.5 million NIH grant to beat Alzheimer's disease and related dementias

Leukemia drug successfully disrupts HER2-positive brain metastasis in animal studies

Vitamin D mediates crosstalk between COVID-19 and osteoporosis

Penn State receives $1.6 million grant to study the link between COVID-19 and cognitive decline

Researchers develop a protein thermal shift chip for COVID-19

Penn-CHOP Kidney Innovation Center focuses on early detection, prevention, and treatment of kidney disease

Researchers report large molecular compounds and nanoscale nanozyme of two traditional Chinese medicines may inhibit COVID-19 signaling

Scientists demonstrate safety of neurosurgical procedure used to measure dopamine and serotonin

Simple computer program may help personalize cancer treatment

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Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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