Pharmacology News and Research

Latest Pharmacology News and Research

Study findings could be harnessed to engineer new botulinum neurotoxin E variants

A team of researchers from the University of California, Irvine, have revealed the first crystal structures of the receptor-binding domain of botulinum neurotoxin E (BoNT/E) in complex with its human neuronal receptors, synaptic vesicle glycoprotein 2A (SV2A).

27 Apr 2023

Insomnia drug shows potential as an effective treatment for opioid use disorder

The insomnia drug suvorexant (Belsomra) might be an effective treatment for opioid use disorder, according to a preclinical study from Scripps Research.

27 Apr 2023

Study uncovers new clues and raises more questions about CRISPR

CRISPR claimed scientific fame for its ability to quickly and accurately edit genes. But, at the core, CRISPR systems are immune systems that help bacteria protect themselves from viruses by targeting and destroying viral DNA and RNA.

27 Apr 2023

UC research examines link between genetics and the presence of opioid use disorder

New research out of the University of Cincinnati examines the association between genetics and the presence of opioid use disorder.

27 Apr 2023

How inert, sleeping bacteria spring back to life

Solving a riddle that has confounded biologists since bacterial spores - inert, sleeping bacteria - were first described more than 150 years ago, researchers at Harvard Medical School have discovered a new kind of cellular sensor that allows spores to detect the presence of nutrients in their environment and quickly spring back to life.

27 Apr 2023

Researchers identify a druggable copper-signaling pathway that drives inflammation

Inflammation is a complex biological process that can eradicate pathogens and promotes repair of damaged tissues.

27 Apr 2023

Melanoma research unveils landscape of DNA and RNA alterations across multiple organs of metastasis

In a new translational study from UCLA Jonsson Comprehensive Cancer Center, researchers analyzed genetic changes in the organs of recently deceased patients to understand how metastatic cutaneous melanoma spreads in those who had initially benefited from precision therapies.

27 Apr 2023

Understanding how biological sex and immune system contribute to shaping the developing brain

Researchers have established that biological sex plays a role in determining an individual's risk of brain disorders.

26 Apr 2023

Prenatal exposure to cannabinoids linked to newborn mortality and respiratory problems

Consumption of cannabis (marijuana) or derivatives during pregnancy can cause respiratory problems for the baby, such as impaired control of breathing and diminished sensitivity to carbon dioxide, both of which favor sudden infant death syndrome.

25 Apr 2023

Drug-metabolizing enzyme may be a major player in safety concerns related to the painkiller diclofenac

Safety concerns related to the widely used painkiller diclofenac may be tied to a little-studied drug-metabolizing enzyme whose expression can vary as much as 3,000 times from one individual to the next, according to new research.

24 Apr 2023

Research findings could help inform more effective therapies for AML

Acute myeloid leukemia (AML) is a type of cancer in which the bone marrow makes a large number of abnormal blood cells. It is the most common type of acute leukemia in adults.

24 Apr 2023

Researchers discover a key player in preventing 'insulin shock'

Just over a century has passed since the discovery of insulin, a time period during which the therapeutic powers of the hormone have broadened and refined. Insulin is an essential treatment for type 1 diabetes and often for type 2 diabetes, as well.

24 Apr 2023

How alcohol intake contributes to increased pain and hypersensitivity

Chronic alcohol consumption may make people more sensitive to pain through two different molecular mechanisms - one driven by alcohol intake and one by alcohol withdrawal.

21 Apr 2023

New biologic inactivates potent opioid and reverses overdose

A new therapeutic designed by Scripps Research chemists can alter the molecular structure of the potent opioid carfentanil, inactivating the opioid and reversing a carfentanil overdose.

18 Apr 2023

Researchers discover the molecule responsible for guiding T cells toward tumors

Immunotherapy, particularly CAR T-Cell treatment for cancer, is extending the lives of many patients. But sometimes the therapy randomly migrates to places it shouldn't go, tucking into the lungs or other noncancerous tissue and causing toxic side effects.

18 Apr 2023

Study sheds light on cardiovascular health of babies exposed to opioids in the womb

A new study sheds light on an understudied aspect of today's opioid crisis: What happens to the cardiovascular health of babies exposed to opioids in the womb.

13 Apr 2023

Male alcohol consumption before conception causes facial growth defects in offspring

According to the U.S. Surgeon General, women should not drink alcoholic beverages during pregnancy because of the risk of birth defects in their unborn child.

12 Apr 2023

Unexpected discovery could inspire new strategies for preventing liver disease and cancer

Liver cancer is the third leading cause of cancer death and the sixth most common cancer type worldwide.

12 Apr 2023

ACC to host annual Advancing the Cardiovascular Care of the Oncology Patient course

The American College of Cardiology will host the annual Advancing the Cardiovascular Care of the Oncology Patient course on April 14-16, 2023, in Washington, DC.

10 Apr 2023

Novel amino acid compound treats nonalcoholic fatty liver disease in non-human primates

A recently developed amino acid compound successfully treats nonalcoholic fatty liver disease in non-human primates - bringing scientists one step closer to the first human treatment for the condition that is rapidly increasing around the world, a study suggests.

10 Apr 2023

Pharmacology News and Research

Latest Pharmacology News and Research

Study findings could be harnessed to engineer new botulinum neurotoxin E variants

Insomnia drug shows potential as an effective treatment for opioid use disorder

Study uncovers new clues and raises more questions about CRISPR

UC research examines link between genetics and the presence of opioid use disorder

How inert, sleeping bacteria spring back to life

Researchers identify a druggable copper-signaling pathway that drives inflammation

Melanoma research unveils landscape of DNA and RNA alterations across multiple organs of metastasis

Understanding how biological sex and immune system contribute to shaping the developing brain

Prenatal exposure to cannabinoids linked to newborn mortality and respiratory problems

Drug-metabolizing enzyme may be a major player in safety concerns related to the painkiller diclofenac

Research findings could help inform more effective therapies for AML

Researchers discover a key player in preventing 'insulin shock'

How alcohol intake contributes to increased pain and hypersensitivity

New biologic inactivates potent opioid and reverses overdose

Researchers discover the molecule responsible for guiding T cells toward tumors

Study sheds light on cardiovascular health of babies exposed to opioids in the womb

Male alcohol consumption before conception causes facial growth defects in offspring

Unexpected discovery could inspire new strategies for preventing liver disease and cancer

ACC to host annual Advancing the Cardiovascular Care of the Oncology Patient course

Novel amino acid compound treats nonalcoholic fatty liver disease in non-human primates

Pittcon Highlights: Pharmaceutical & Biologic eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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