Pharmacology News and Research

Latest Pharmacology News and Research

Researchers discover neuronal mechanism involved in the learning of maternal behavior

Various conditions such as postpartum depression or postpartum psychosis can lead to an alteration in maternal behavior and disrupt the mother-child bonding process.

8 Nov 2022

Environmental toxicants contribute to obesity and metabolic disease

In a recent study published in the Current Opinion in Pharmacology journal, researchers assessed the impact of environmental toxicants and brown adipose tissue (BAT) on obesity and metabolic disorders.

4 Nov 2022

Inflammation increases the expression of risk gene in first-episode schizophrenia patients

Schizophrenia patients have fewer connections between nerve cells. This is believed to be caused by genetic risk variants leading to an excessive elimination of nerve cell connections by the immune cells of the brain.

3 Nov 2022

Researchers unravel how the brain chemical dopamine relates to schizophrenia

Researchers at the Lieber Institute for Brain Development (LIBD) believe they have solved a riddle that has challenged scientists for more than 70 years: how the brain chemical dopamine relates to schizophrenia, the often-devastating brain disorder characterized by delusional thinking, hallucinations and other forms of psychosis.

1 Nov 2022

Researchers develop special molecules that stimulate the immune system

Surgery, radiation, and chemotherapy are the three main therapies used to treat cancerous tumors. The doctoral research network 'Magicbullet::Reloaded'is investigating another approach, with 15 doctoral researchers developing special molecules that stimulate the immune system to destroy tumor cells. In a video, network members explain how doctoral researchers gain valuable experience and research opportunities as part of the network.

1 Nov 2022

Study finds sexual dimorphism in the development of vascular insulin resistance induced by obesogenic lifestyle

A new study from the University of Missouri School of Medicine is the first evidence in humans that short-term lifestyle changes can disrupt the response to insulin of blood vessels. It's also the first study to show men and women react differently to these changes.

27 Oct 2022

New discovery may change the textbook model of GPCR-mediated signaling

Researchers at University of California San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse drugs.

27 Oct 2022

RIT professor receives grant to investigate new therapeutic approaches for scleroderma

More collagen in the human body is not always good, and Karin Wuertz-Kozak is investigating how disease progresses because of the increase in this important protein.

25 Oct 2022

Researchers identify a natural defense mechanism that protects cells from Pseudomonas infection

Pseudomonas aeruginosa (P.a.) are resistant to most antibiotics and cause life-threatening infections of wounds or the lungs.

21 Oct 2022

Male mice three times more likely than females to survive E. coli infection

Scientists at UC San Francisco have developed a new way of looking at sex-biased diseases that is rooted in evolutionary biology.

20 Oct 2022

Researchers circumvent a key mechanism in castration-resistant prostate cancer

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have shown that they can circumvent a key mechanism in castration-resistant prostate cancer (CRPC) and possibly make immunotherapies more effective.

20 Oct 2022

Adaptation-proof SARS-CoV-2 vaccine design is one step closer to reality

A vaccine design approach that could protect against new variants of SARS-CoV-2, the virus that causes COVID-19, but also potentially protects against other coronaviruses is one step closer to reality as a result of Penn State College of Medicine research.

18 Oct 2022

Epigenetic changes related to Parkinson's disease are different in men and women, study says

The epigenetic changes linked to Parkinson's disease – a nervous system disorder that afflicts nearly 1 million Americans – are different in men and women, according to a new Rutgers study published in NPJ Parkinson's Disease.

18 Oct 2022

What is the impact of COVID-19 and organophosphates on cardiac health?

In a new study, researchers discussed the impacts of organophosphates (OP) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on cardiovascular (CVS) health.

17 Oct 2022

Inhalation therapeutics against COVID-19

A recent study published in the Pulmonary Pharmacology & Therapeutics journal described different inhalation therapeutic agents for treating respiratory viral infections like coronavirus disease 2019 (COVID-19).

17 Oct 2022

Multi-center analysis shines light on invasive lobular carcinoma

A multi-center analysis of patients with invasive lobular carcinoma, or ILC - the second most common histological subtype of invasive breast cancer in the U.S. - showed that, despite its prevalence, ILC is detected later and has worse outcomes than the predominant subtype of invasive breast cancer, known as invasive ductal carcinoma (IDC), or no special type.

14 Oct 2022

High-sugar diet lowers the ability of the taste system to sense sweetness

For many people, a high-sugar diet has become almost accidental. Three-quarters of food in the supermarket has added sugar, according to University of Michigan researcher Monica Dus, leading the scientist to wonder whether our sense of taste can become dulled to sweetness.

12 Oct 2022