Pharmacology News and Research

Latest Pharmacology News and Research

Researchers develop a long-acting injectable formulation of the anti-TB drug rifabutin

In 2020, more than 1.5 million people around the world died of tuberculosis, marking the first time in more than a decade that annual TB deaths had increased and demonstrating the global need for better access to treatments.

8 Aug 2022

Should pregnant women be included clinical trials?

The current study reports some of the scientific, ethical, and legal considerations that will support the inclusion of pregnant women in future research.

8 Aug 2022

Extracellular vesicle-based surface protein assay likely to lead to a better way to detect early-stage hepatocellular carcinoma

Primary liver cancer, the third-leading cause of cancer-related death worldwide, takes more than 30,000 lives in the United States each year. The high mortality rates can be attributed in part to the fact that a significant portion of the patients are detected at a late stage, when potentially curative treatments are no longer an option. Unfortunately, today's screening methods are not able to routinely provide accurate, early detection.

5 Aug 2022

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

In this interview, we speak to Tom Kostrzewski, VP of Science and Technology at CN Bio, about their organ-on-a-chip product and the future of drug discovery.

From CN Bio Innovations Ltd 3 Aug 2022

NUS study provides evidence of the cytotoxic effect of black cardamom on lung cancer cells

The main challenges associated with existing lung cancer drugs are severe side effects and drug resistance. There is hence a constant need to explore new molecules for improving the survival rate and quality of life of lung cancer patients.

1 Aug 2022

Two Weill Cornell doctoral students receive Gilliam Fellowships for Advanced Study from HHMI

Two doctoral students at Weill Cornell Graduate School of Medical Sciences have been awarded prestigious Gilliam Fellowships for Advanced Study from the Howard Hughes Medical Institute.

29 Jul 2022

Study highlights impaired ketogenesis as a potential confounder of severe COVID-19

In severe Covid-19 patients, the metabolism produces insufficient amounts of certain energy-rich compounds called ketone bodies. However, these energy carriers are needed by two important cell types in the immune system in order to fight the virus effectively.

28 Jul 2022

Lactating mice expose their feeding pups to triclosan resulting in early signs of liver damage

In mouse studies, researchers at University of California San Diego School of Medicine report that lactating mothers expose their feeding pups to triclosan, an antimicrobial commonly used in consumer products, resulting in early signs of liver damage that can eventually lead to more serious impairment and illness, such as nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH).

28 Jul 2022

Genetic variations in one serotonin receptor could be the reason behind psychedelic treatment disparity

When all else fails, some patients trying to overcome alcoholism, severe depression or anxiety, and even cluster headaches, turn to psychedelic drugs, which clinical research has shown can help treat individuals with these conditions, sometimes with dramatically positive results.

27 Jul 2022

Researchers unravel how one gut bacterium influences immunity

From immunity to metabolism to mental health, it seems like the gut microbiome has been linked to every aspect of human health and disease.

27 Jul 2022

UTHSC investigators secure $2.16 million to test a new way to combat neurodegenerative disorders

The National Institute on Aging recently awarded $2.16 million to a team of investigators from the University of Tennessee Health Science Center (UTHSC) testing a new way to combat the root cause of neurodegenerative disorders such as Alzheimer's Disease.

22 Jul 2022

Scientists find new evidence against using BET inhibitors to treat COVID-19

A while ago, some researchers had suggested that blocking a set of proteins, known as bromodomain and extraterminal (BET) proteins, might be a way to fight COVID-19.

20 Jul 2022

Men with hematopoietic mosaic loss of Y chromosome have worse prognosis for heart failure

research group led by Dr. Soichi Sano, a specially appointed lecturer in the Department of Cardiovascular Medicine, Graduate School of Medicine, Osaka Metropolitan University, revealed that men with hematopoietic mosaic loss of Y chromosome (mLOY) — meaning men with an increase, in the blood, of cells that have lost the male sex chromosome — have a worse prognosis for heart failure due to fibrosis progression in the heart.

15 Jul 2022

The Mark Foundation for Cancer Research announces latest ASPIRE awards for eight outstanding projects

The Mark Foundation for Cancer Research announced eight outstanding research projects to receive its latest class of ASPIRE awards.

14 Jul 2022

Y chromosome loss in men can lead to deadly heart failure, research shows

The loss of the male sex chromosome as many men age causes the heart muscle to scar and can lead to deadly heart failure, new research from the University of Virginia School of Medicine shows.

14 Jul 2022

New transport system exemplifies the potential of a de novo design of peptides and proteins

A novel peptide developed at the Universities of Bayreuth and Bristol is eminently suited for the targeted transport of molecules, for example of active substances and dyes, into the cells of mammals.

14 Jul 2022

Study describes biochemical pathway that leads to inflammation characteristic of autoimmune diseases

Mitochondria are self-contained organelles (they possess their own mini-chromosome and DNA) residing within cells and are charged with the job of generating the chemical energy needed to fuel functions essential to life and well-being.

13 Jul 2022

Mount Sinai receives $4.2 million to establish a Proteogenomic Data Analysis Center

The Office of Cancer Clinical Proteomics Research at the National Cancer Institute has awarded $4.2 million over five years to Mount Sinai researchers establishing a Proteogenomic Data Analysis Center to advance cancer research and treatments.

13 Jul 2022

How common is pediatric cannabis use and what are the risks?

New research evaluated the recent usage of marijuana and its derivative products, their effects and clinical manifestations, perceptions, pharmaceutics, epidemiological studies, and the long-term ramifications in pediatric populations.

12 Jul 2022

Researchers challenge centuries-old beliefs about limb regeneration

Ken Muneoka is no stranger to disrupting the field of regeneration; for example, in a 2019 ground-breaking publication in Nature, the Texas A&M University College of Veterinary Medicine & Biomedical Sciences professor proved for the first time that joint regeneration in mammals was possible.

6 Jul 2022

Pharmacology News and Research

Latest Pharmacology News and Research

Researchers develop a long-acting injectable formulation of the anti-TB drug rifabutin

Should pregnant women be included clinical trials?

Extracellular vesicle-based surface protein assay likely to lead to a better way to detect early-stage hepatocellular carcinoma

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

NUS study provides evidence of the cytotoxic effect of black cardamom on lung cancer cells

Two Weill Cornell doctoral students receive Gilliam Fellowships for Advanced Study from HHMI

Study highlights impaired ketogenesis as a potential confounder of severe COVID-19

Lactating mice expose their feeding pups to triclosan resulting in early signs of liver damage

Genetic variations in one serotonin receptor could be the reason behind psychedelic treatment disparity

Researchers unravel how one gut bacterium influences immunity

UTHSC investigators secure $2.16 million to test a new way to combat neurodegenerative disorders

Scientists find new evidence against using BET inhibitors to treat COVID-19

Men with hematopoietic mosaic loss of Y chromosome have worse prognosis for heart failure

The Mark Foundation for Cancer Research announces latest ASPIRE awards for eight outstanding projects

Y chromosome loss in men can lead to deadly heart failure, research shows

New transport system exemplifies the potential of a de novo design of peptides and proteins

Study describes biochemical pathway that leads to inflammation characteristic of autoimmune diseases

Mount Sinai receives $4.2 million to establish a Proteogenomic Data Analysis Center

How common is pediatric cannabis use and what are the risks?

Researchers challenge centuries-old beliefs about limb regeneration

Pittcon Highlights: Pharmaceutical & Biologic eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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