Pharmacology News and Research

Latest Pharmacology News and Research

Molecular pathway allows cells to sense when their lipid supplies become depleted

UT Southwestern researchers have discovered a molecular pathway that allows cells to sense when their lipid supplies become depleted, prompting a flurry of activity that prevents starvation.

18 May 2022

New tool can accurately predict which hospitalized patients need critical care for COVID-19

Scientists have developed and validated an algorithm that can help healthcare professionals identify who is most at risk of dying from COVID-19 when admitted to a hospital, reports a study published today in eLife.

17 May 2022

Targeting specific neurons modulates memory retrieval and alters anxiety-like behaviors in mice

We humans lose mental acuity, an unfortunate side effect of aging. And for individuals with neurodegenerative conditions such as Alzheimer's and Parkinson's, the loss of cognitive function often accompanied by mood disorders such as anxiety is a harrowing experience.

16 May 2022

Rutgers study identifies key protein for brain stem cell longevity

A receptor that was first identified as necessary for insulin action, that also is located on the neural stem cells found deep in the brains of mice, is pivotal for brain stem cell longevity, according to a Rutgers study, a finding that has important implications for brain health and future therapies for brain disorders.

11 May 2022

How new Insights into ESR1 Mutant Breast Cancers may lead to Novel Therapy Targets

In this interview, we speak to Steffi Oesterreich, PH.D., from the University of Pittsburgh, about how new insights into a gene mutation present in 20-30% of breast cancer recurrences may have a silver lining, leading to novel treatment opportunities.

9 May 2022

Antigen-presenting cancer-associated fibroblasts offer a new target to fight pancreatic cancer

Scar-like cells that make up a sizable portion of malignant pancreatic tumors and shield these cancers from immune attack are derived from mesothelial cells that line tissues and organs, a new study led by UT Southwestern researchers suggests.

6 May 2022

Study assesses the efficacy and safety of lithium treatment in patients infected with severe SARS-CoV-2

Researchers assessed the efficacy and safety of using lithium for coronavirus disease 2019 (COVID-19) treatment.

5 May 2022

Discovery could lead to new treatments to minimize cravings in people with addictions

For some people with alcohol use disorder, it might be the sight of a familiar bar or a favorite bottle; for others, it might be the feeling of leaving the office after a stressful day at work or stepping into a crowded party. Most people who struggle with drug or alcohol addiction have particular cues that set off their cravings.

4 May 2022

Study finds brain circuit controlling drug withdrawal-induced anxiety and reinstatement

New research from the University of California, Irvine, finds that drug withdrawal-induced anxiety and reinstatement of drug seeking behaviors are controlled by a single pathway in the brain and centered around dopamine cells.

4 May 2022

Scientists discover a potential new method of active immunization to prevent Alzheimer's disease

During experiments in animal models, researchers at the University of Kansas have discovered a possible new approach to immunization against Alzheimer's disease (AD).

4 May 2022

University of Arizona, Oklahoma State University join forces to combat opioid crisis and chronic pain

Robert C. Robbins, MD, president of the University of Arizona, and Kayse Shrum, DO, president of Oklahoma State University, today announced the two institutions’ academic medical centers have joined forces to combat the opioid crisis and chronic pain through research, treatment and education.

30 Apr 2022

New insights into how NANOG protein facilitates the activation of human cell pluripotency

There are cells in the body known as pluripotent stem cells that are yet to specialize in a particular biological function.

28 Apr 2022

Researchers unravel why neuropsychiatric symptoms appear in Alzheimer's patients before memory loss

Researchers from Indiana University School of Medicine are studying why neuropsychiatric symptoms, such as apathy and irritability, appear in most Alzheimer's disease patients before the onset of memory loss.

28 Apr 2022

New data may change the standard of care for patients with advanced non-small cell lung cancer

The phase 2 clinical trial of a multi-center study known as the COAST clinical trial has demonstrated improved outcomes using immunotherapy combinations for patients with unresectable stage III non-small cell lung cancer, according to researchers at Yale Cancer Center and participating organizations.

25 Apr 2022

New photo-responsive nanomedicine for light-controlled colorectal cancer therapy

A research team from Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, The University of Hong Kong (HKUMed), has developed a photo-responsive nanomedicine for light-controlled colorectal cancer therapy.

21 Apr 2022

Study highlights mortality risk and healthcare utilization of people with treatment-resistant depression

Researchers from the Department of Pharmacology and Pharmacy, Department of Medicine, Department of Pediatrics and Adolescent Medicine of the LKS Faculty of Medicine, The University of Hong Kong (HKUMed) and Department of Social Work and Social Administration at The University of Hong Kong (HKU).

21 Apr 2022

New technology enables single-cell sorting based on functional outputs

For nearly 40 years, drugmakers have used genetically engineered cells as tiny drug factories. Such cells can be programmed to secrete compounds that yield drugs used to treat cancer and autoimmune conditions such as arthritis.

20 Apr 2022

Mutated gene found in breast cancer recurrences may help tumors to become more aggressive

A mutated gene found in more than 20% to 30% of breast cancer recurrences may help tumors become more aggressive and promote metastasis, according to a pair of new studies that uncover mechanisms behind these processes and point to new therapy targets.

20 Apr 2022

Using customized 'mini-antibodies' to mitigate chronic inflammation

Researchers at the Universities of Bonn and Sao Paulo have succeeded in mitigating chronic inflammation in mice using customized "mini-antibodies."

19 Apr 2022

Study examines how race and sex influence tacrolimus pharmacokinetics in kidney transplant recipients

Kidney transplant survival is shorter, on average, in Black recipients compared to white recipients receiving similar treatment.

18 Apr 2022

Pharmacology News and Research

Latest Pharmacology News and Research

Molecular pathway allows cells to sense when their lipid supplies become depleted

New tool can accurately predict which hospitalized patients need critical care for COVID-19

Targeting specific neurons modulates memory retrieval and alters anxiety-like behaviors in mice

Rutgers study identifies key protein for brain stem cell longevity

How new Insights into ESR1 Mutant Breast Cancers may lead to Novel Therapy Targets

Antigen-presenting cancer-associated fibroblasts offer a new target to fight pancreatic cancer

Study assesses the efficacy and safety of lithium treatment in patients infected with severe SARS-CoV-2

Discovery could lead to new treatments to minimize cravings in people with addictions

Study finds brain circuit controlling drug withdrawal-induced anxiety and reinstatement

Scientists discover a potential new method of active immunization to prevent Alzheimer's disease

University of Arizona, Oklahoma State University join forces to combat opioid crisis and chronic pain

New insights into how NANOG protein facilitates the activation of human cell pluripotency

Researchers unravel why neuropsychiatric symptoms appear in Alzheimer's patients before memory loss

New data may change the standard of care for patients with advanced non-small cell lung cancer

New photo-responsive nanomedicine for light-controlled colorectal cancer therapy

Study highlights mortality risk and healthcare utilization of people with treatment-resistant depression

New technology enables single-cell sorting based on functional outputs

Mutated gene found in breast cancer recurrences may help tumors to become more aggressive

Using customized 'mini-antibodies' to mitigate chronic inflammation

Study examines how race and sex influence tacrolimus pharmacokinetics in kidney transplant recipients

Pittcon Highlights: Pharmaceutical & Biologic eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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