Pharmacology News and Research

Latest Pharmacology News and Research

Study provides better understanding of the degenerative underpinnings of Parkinson’s disease

Northwestern investigators have discovered the molecular signature of a subset of dopaminergic neurons with an increased vulnerability to degeneration.

12 Dec 2021

UTSW study points to a new way to fight parasitic nematode diseases

Combining two agents to block a parasitic worm's life cycle boosted survival from a potentially deadly tropical disease to 85% in animal models, far better than either treatment alone, according to a proof-of-concept study led by UT Southwestern Medical Center pharmacologists.

11 Dec 2021

Higher intake of plant-based foods could help reduce the risk of cognitive decline due to aging

A diet rich in plant products reduces the risk of cognitive impairment and dementia in the elderly. This is the result of a study by the Biomarkers and Nutritional Food Metabolomics Research Group of the Faculty of Pharmacy and Food Sciences of the University of Barcelona and the CIBER on Frailty and Healthy Aging.

9 Dec 2021

Study examines the extent of medication-related harm in pediatric intensive care units

In an observational study conducted across three pediatric intensive care units (PICUs) in England over a three-month period in 2019, one-sixth of patients experienced at least one adverse drug event, in which they were harmed by a medication.

8 Dec 2021

Study shows how senescent cells can be an underlying cause of kidney damage

A study in mice by researchers at Georgetown Lombardi Comprehensive Cancer Center has found that stress and tissue damage initiated by angiotensin II, a molecule that is known to increase blood pressure and stiffening in the linings of blood vessels, leads to cellular senescence, a process by which a cell ages and permanently stops dividing but does not die.

8 Dec 2021

Study analyzes the contribution of AI to cancer patient care and vaccine design

Artificial Intelligence/Machine Learning (AI/ML) is the development of computer systems that are able to perform tasks that would normally require human intelligence. AI/ML is used by people every day, for example, while using smart home devices or digital voice assistants.

8 Dec 2021

Novel AI-based system models the progression of chronic diseases as patients age

Using artificial intelligence, a team of University at Buffalo researchers has developed a novel system that models the progression of chronic diseases as patients age.

7 Dec 2021

New protein variant underlies the ability of gastric cancers to resist chemotherapy

A new protein variant underlies the ability of gastric cancers to resist an otherwise effective family of chemotherapy drugs, according to a study by a multidisciplinary team at Weill Cornell Medicine. The results suggest a treatment strategy that could improve the prognoses of many patients with cancer.

6 Dec 2021

Northwestern researchers continue to tackle every facet of COVID-19 pandemic

As the COVID-19 pandemic nears the two-year mark, Northwestern Medicine scientists continue to tackle every facet of the disease, from investigating coronavirus vaccines' potential for providing immunity against similar coronaviruses to developing novel rapid antigen-based tests and examining disparities in COVID-19 case and mortality rates in Chicago.

30 Nov 2021

Clinical drug research for the treatment of CNS and neurological disorders

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders.

29 Nov 2021

Simple change can maximize a single cell's production of extracellular vesicles

A simple change in the way donor cells are processed can maximize a single cell's production of extracellular vesicles, which are small nanoparticles naturally secreted by cells, according to new research from researchers at the University of Illinois Chicago.

29 Nov 2021

Exosomes involved in the progression of breast cancer in patients with obesity, diabetes

Obesity, insulin resistance and Type 2 diabetes are risk factors for breast cancer in post-menopausal women. The metabolic and inflammatory complications of obesity have a role in the formation of cancer.

24 Nov 2021

New study uncovers a mechanism of sleep in zebrafish

Why do humans spend a third of their lives sleeping? Why do animals sleep? Throughout evolution sleep has remained universal and essential to all organisms with a nervous system, including invertebrates such as flies, worms, and even jellyfish.

21 Nov 2021

$10 million gift helps launch the Colton Center for Autoimmunity at Penn

Thanks to a generous $10 million gift from Stewart and Judy Colton, the Perelman School of Medicine at the University of Pennsylvania will continue to be on the leading edge of autoimmune research and care with the launch of the Colton Center for Autoimmunity at Penn.

18 Nov 2021

Nanocomputing agent controls the function of protein involved in cell movement, cancer metastasis

The creation of nanoscale computers for use in precision health care has long been a dream of many scientists and health care providers.

16 Nov 2021

New metabolic vulnerabilities of subsets of triple-negative breast cancer discovered

Researchers have identified a metabolic enzyme and pathway in some triple-negative breast cancer (TNBC) patients, which they hope could serve as a biomarker to select patients to receive targeted therapy.

16 Nov 2021

Oral PCSK9-inhibitor highly effective at reducing high levels of LDL cholesterol, studies show

Results from two early clinical studies show the first version of an oral PCSK9-inhibitor cholesterol-lowering medicine was well tolerated and highly effective at reducing high levels of LDL cholesterol, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2021.

15 Nov 2021

Microbiome discovery may help improve treatment for patients with gastrointestinal diseases

University of Calgary researchers probing the gut -; "the inner tube of life" -; have for the first time discovered specific factors in its workings that in the future may help improve treatment for patients facing gut damage or gastrointestinal disease.

12 Nov 2021

New target for drug development could fill a major gap in depression treatment

Vanderbilt researchers found that ketamine's rapid antidepressant action is due to specific synaptic effects.

10 Nov 2021

UArizona researchers get closer to developing a safe, effective non-opioid pain reliever

Researchers at the University of Arizona Health Sciences are closer to developing a safe and effective non-opioid pain reliever after a study showed that a new compound they created reduces the sensation of pain by regulating a biological channel linked to pain.

10 Nov 2021

Pharmacology News and Research

Latest Pharmacology News and Research

Study provides better understanding of the degenerative underpinnings of Parkinson’s disease

UTSW study points to a new way to fight parasitic nematode diseases

Higher intake of plant-based foods could help reduce the risk of cognitive decline due to aging

Study examines the extent of medication-related harm in pediatric intensive care units

Study shows how senescent cells can be an underlying cause of kidney damage

Study analyzes the contribution of AI to cancer patient care and vaccine design

Novel AI-based system models the progression of chronic diseases as patients age

New protein variant underlies the ability of gastric cancers to resist chemotherapy

Northwestern researchers continue to tackle every facet of COVID-19 pandemic

Clinical drug research for the treatment of CNS and neurological disorders

Simple change can maximize a single cell's production of extracellular vesicles

Exosomes involved in the progression of breast cancer in patients with obesity, diabetes

New study uncovers a mechanism of sleep in zebrafish

$10 million gift helps launch the Colton Center for Autoimmunity at Penn

Nanocomputing agent controls the function of protein involved in cell movement, cancer metastasis

New metabolic vulnerabilities of subsets of triple-negative breast cancer discovered

Oral PCSK9-inhibitor highly effective at reducing high levels of LDL cholesterol, studies show

Microbiome discovery may help improve treatment for patients with gastrointestinal diseases

New target for drug development could fill a major gap in depression treatment

UArizona researchers get closer to developing a safe, effective non-opioid pain reliever

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Pharmacology News and Research

Latest Pharmacology News and Research

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How can microdialysis benefit drug development

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