Pharmacology News and Research

Latest Pharmacology News and Research

New biomarkers could help determine synaptic damage and neurodegeneration in Alzheimer's

Alzheimer's disease is the main neurodegenerative disease in old people for which there is no treatment or efficient prevention yet.

10 Nov 2021

Cancer drugs could be repurposed as potential therapies for Alzheimer's disease

Existing and emerging cancer drugs could be repurposed as therapies to be tested in clinical trials for people at genetic risk of Alzheimer's disease, according to a new study published in Science Advances.

10 Nov 2021

Identifying an important protein for motor coordination

News-Medical speaks to Professor Jorge Ruas about how he has identified an important protein involved in motor coordination.

10 Nov 2021

Ion channel mechanosensor plays a key role in regulating the speed of skin wound healing

PIEZO1, an ion channel mechanosensor found within cells, has been revealed to play a key role in regulating the speed of skin wound healing by researchers at the University of California, Irvine.

10 Nov 2021

SBIR grant awarded to develop treatment for alcoholic liver disease-associated hepatorenal syndrome

The Institute of Human Virology (IHV) at the University of Maryland School of Medicine and MitoPower LLC were awarded an SBIR (Small Business Innovation Research) grant of up to $6.5 million over five years from the National Institutes of Health's National Institute on Alcohol Abuse and Alcoholism.

9 Nov 2021

Therapeutics that target ceramides may help treat cardiometabolic disease

Therapeutics that target lipids called ceramides might hold potential for treating cardiometabolic disease, argues a review article published November 5th in the journal Trends in Pharmacological Sciences.

7 Nov 2021

Chlorophyll catabolite pheophorbide A shows potential against SARS-CoV-2

A new study identifies a potent SARS-CoV-2 antiviral, Pheophorbide a (PheoA), which is a compound derived from the plant Marchantia polymorpha L.

27 Oct 2021

Northwestern scientists receive awards totaling nearly $18 million for Parkinson's disease research

Northwestern University scientists have received two awards totaling nearly $18 million for Parkinson's disease research from The ASAP Collaborative Research Network, a program of the Aligning Science Across Parkinson's (ASAP) initiative being implemented through The Michael J. Fox Foundation.

27 Oct 2021

HCV treatment decreases protein activity levels involved in liver cirrhosis, research shows

Researchers at the Medical University of South Carolina report in the Journal of Viral Hepatitis that the activity levels of the proteins involved in liver scarring, or cirrhosis, begin to decrease immediately after treatment for the hepatitis C virus (HCV), suggesting the possibility of early healing.

26 Oct 2021

Case Western Reserve secures $16 million to understand the relation between substance use and HIV

The use of opioids, methamphetamines, cocaine and other stimulants is the second-most-common cause of exposure to HIV among those in the United States diagnosed with the virus that causes AIDS.

25 Oct 2021

Molecular mechanism that controls the transition from acute to chronic pain revealed

A new study led by University of California, Irvine researchers is the first to reveal the specific molecular mechanism that controls the transition from acute to chronic pain, and identifies this mechanism as a critical target for disease-modifying medicines.

25 Oct 2021

Study findings may lead to new treatments to fight deadly C. difficile infections

A University of California, Irvine-led study suggests that the glucosyltransferase domain (GTD) is an ideal molecular target for therapeutic interventions for Clostridioides difficile infection (CDI). These findings may lead to new treatments to fight this deadly disease.

22 Oct 2021

Researchers employ novel algorithm to identify candidate cancer drugs for pulmonary hypertension

By combining computational and experimental approaches, University of Pittsburgh School of Medicine and Prairie View A&M University researchers identified cancer drugs that show promise for treating pulmonary hypertension, or PH, a rare and incurable lung disease.

21 Oct 2021

Skeletal muscle in individuals with type 2 diabetes has a different circadian rhythm, research shows

Almost all cells regulate their biological processes over a 24-hour period, otherwise called a cell's circadian rhythm. To do so, cells use a biological clock that cycles different genes on and off throughout the day and night. Scientists already know that our metabolic health can suffer when our biological clock breaks down, due to shift work or sleep disorders, for example. However, it's unclear how exactly the biological clock of people with type 2 diabetes differs from healthy people.

21 Oct 2021

Study paves the way for development of new therapeutic strategies to treat addiction

Drug addiction is a psychiatric disorder for which no pharmacological treatment with long-term efficacy currently exists. All addictive substances share the property of raising concentrations of the neurotransmitter dopamine within brain regions forming the neural reward circuit.

21 Oct 2021

Pharmacology News and Research

Latest Pharmacology News and Research

New biomarkers could help determine synaptic damage and neurodegeneration in Alzheimer's

Cancer drugs could be repurposed as potential therapies for Alzheimer's disease

Identifying an important protein for motor coordination

Ion channel mechanosensor plays a key role in regulating the speed of skin wound healing

SBIR grant awarded to develop treatment for alcoholic liver disease-associated hepatorenal syndrome

Therapeutics that target ceramides may help treat cardiometabolic disease

Chlorophyll catabolite pheophorbide A shows potential against SARS-CoV-2

Northwestern scientists receive awards totaling nearly $18 million for Parkinson's disease research

HCV treatment decreases protein activity levels involved in liver cirrhosis, research shows

Case Western Reserve secures $16 million to understand the relation between substance use and HIV

Molecular mechanism that controls the transition from acute to chronic pain revealed

Study findings may lead to new treatments to fight deadly C. difficile infections

Researchers employ novel algorithm to identify candidate cancer drugs for pulmonary hypertension

Skeletal muscle in individuals with type 2 diabetes has a different circadian rhythm, research shows

Study paves the way for development of new therapeutic strategies to treat addiction

Brain's motor cortex may play a larger role in Parkinson’s disease, study reveals

Famous scientist joins NYU Langone’s Division of Rheumatology

Research reveals how daily circadian rhythms help to change heart function

Researchers explore how opioids may have become so widely abused

Researchers identify neurons and signaling pathways that make sexually receptive females more active

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Pharmacology News and Research

Latest Pharmacology News and Research

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Automating research - solutions and best practices

How can microdialysis benefit drug development

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