Pharmacology News and Research

Latest Pharmacology News and Research

New method can help identify potential anti-cancer drugs at a high pace

The enzymes in human cells known as histone deacetylases, or HDACs, are targets for a handful of anticancer drugs because of their ability to affect gene expression.

25 Jan 2021

Specific NSAIDs are metabolized by acyl-CoA synthetases leading to liver toxicity

Liver injury is a rare side effect of nonsteroidal anti-inflammatory drugs (NSAIDs), which are frequently used for daily pain control.

22 Jan 2021

Consuming caffeinated coffee can temporarily mitigate repercussions of reduced sleep

A new study exploring the impact of repeated sleep loss during a simulated working week has found that consuming caffeinated coffee during the day helps to minimize reductions in attention and cognitive function, compared to decaffeinated coffee.

22 Jan 2021

New model shows key role of innate immunity in controlling COVID-19 viral load

Since SARS-CoV-2 was identified in December 2019, researchers have worked feverishly to study the novel coronavirus. Although much knowledge has been gained, scientists still have a lot to learn about how SARS-CoV-2 interacts with the human body, and how the immune system fights it.

21 Jan 2021

Pharmacists play key role in managing medication-based therapies for older patients

Pharmacists play an important role in managing medication-based therapies for older community-dwelling patients, according to a study published in the British Journal of Clinical Pharmacology.

21 Jan 2021

Potentially promising therapeutic combination for renal cell carcinoma uncovered

Renal cell carcinoma (RCC) is the most common form of cancer of the kidney. In 2018, there were an estimated 403,000 new cases of RCC and 175,000 deaths due to kidney cancer worldwide.

20 Jan 2021

Lab study reveals effective treatment for COVID-19

A new potential therapy for COVID-19 developed by researchers at Rush University Medical Center has shown success in preventing the disease's symptoms in mice.

14 Jan 2021

Novel compound appears to protect myelin and nerve fibers

A compound developed at Oregon Health & Science University appears to protect nerve fibers and the fatty sheath, called myelin, that covers nerve cells in the brain and spinal cord.

13 Jan 2021

Study reveals cardiac protein as a new target for different types of heart disease

Like a failing fuel pump that causes a loss of engine power in a car, a diseased heart can take a serious toll on the body's performance. For some patients, tasks like walking up a flight of stairs or walking across a room eventually turn into exhausting endeavors.

13 Jan 2021

Study: Sugar substitute doesn't lead to the development of diabetes in healthy adults

For those trying to live a healthy lifestyle, the choice between sugar and artificial sweeteners such as saccharin can be confusing.

12 Jan 2021

UTSW study uncovers a gene linked to growth of breast cancer

A team of UT Southwestern researchers has identified a gene involved in the growth of breast cancer, a finding that could lead to potential new targets for treatment.

12 Jan 2021

Researchers aim to improve cognitive performance, mobilize the brain's reserve mechanisms

Which neurobiological principles prevent us as humans from fully utilizing our own cognitive abilities and what are the performance limits of our brains?

8 Jan 2021

Researchers develop new sequencing-based approach for pathogen discovery

A sequencing-based solution can be utilized to determine infection clearance and microbiota recovery. Next, the researchers will apply the technique to investigate the coronavirus disease.

7 Jan 2021

CytoDel successfully delivers neuronal antibody in animal models of botulism

CytoDel, Inc., a privately-held corporation, today announces the publication of preclinical data on the Company's lead product, Cyto-111, in the peer-reviewed journal, Science Translational Medicine. The complete text of the article titled, "Neuronal Delivery of Antibodies has Therapeutic Effects in Animal Models of Botulism," can be found here.

7 Jan 2021

Repurposed drug can treat hearing loss in humans

According to the World Health Organization, around 466 million people worldwide have disabling hearing loss, a number the organization projects will double by 2050 to affect 1 in 10 people.

7 Jan 2021

USF researchers discover promising new compound to open constricted airways

Despite the progress made in managing asthma and chronic obstructive pulmonary disease (COPD), poorly controlled symptoms for both respiratory diseases can lead to severe shortness of breath, hospitalizations or even death.

4 Jan 2021

FDA-approved COVID-19 drug should be used cautiously, says UC researcher

While the world has its eyes on vaccines to stop the spread of coronavirus, therapeutics are still necessary to treat hospitalized patients. One of these treatments, remdesivir, is the first and only antiviral agent of its kind that the U.S. Food and Drug Administration (FDA) has approved so far for COVID-19.

3 Jan 2021

Anesthesia and sleep have surprisingly similar effects on brain activity, finds study

What happens in the brain when our conscious awareness fades during general anesthesia and normal sleep? Finnish scientists studied this question with novel experimental designs and functional brain imaging.

29 Dec 2020

Absence of anti-tumor protein may cause resistance to EGFR-targeting therapies

The absence of a protein that works to prevent tumor formation may explain why some patients are resistant to a common cancer therapy, according to Penn State College of Medicine researchers.

21 Dec 2020

Stem cell engineering used to identify gene signaling pathway linked to schizophrenia

Using human-induced pluripotent stem cells engineered from a single family's blood samples, a gene signaling pathway linked to a higher risk for developing schizophrenia was discovered by scientists at The University of Texas Health Science Center at Houston.

21 Dec 2020

Pharmacology News and Research

Latest Pharmacology News and Research

New method can help identify potential anti-cancer drugs at a high pace

Specific NSAIDs are metabolized by acyl-CoA synthetases leading to liver toxicity

Consuming caffeinated coffee can temporarily mitigate repercussions of reduced sleep

New model shows key role of innate immunity in controlling COVID-19 viral load

Pharmacists play key role in managing medication-based therapies for older patients

Potentially promising therapeutic combination for renal cell carcinoma uncovered

Lab study reveals effective treatment for COVID-19

Novel compound appears to protect myelin and nerve fibers

Study reveals cardiac protein as a new target for different types of heart disease

Study: Sugar substitute doesn't lead to the development of diabetes in healthy adults

UTSW study uncovers a gene linked to growth of breast cancer

Researchers aim to improve cognitive performance, mobilize the brain's reserve mechanisms

Researchers develop new sequencing-based approach for pathogen discovery

CytoDel successfully delivers neuronal antibody in animal models of botulism

Repurposed drug can treat hearing loss in humans

USF researchers discover promising new compound to open constricted airways

FDA-approved COVID-19 drug should be used cautiously, says UC researcher

Anesthesia and sleep have surprisingly similar effects on brain activity, finds study

Absence of anti-tumor protein may cause resistance to EGFR-targeting therapies

Stem cell engineering used to identify gene signaling pathway linked to schizophrenia

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Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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