Pharmacology News and Research

Latest Pharmacology News and Research

Designing antimalarials with multiple targeting mechanisms of action

Malaria remains a serious global health threat. While the current discoveries of antimalarials are almost totally focused on single mode-of-action inhibitors, multi-targeting inhibitors are highly desired to overcome the increasingly serious drug resistance.

18 Aug 2021

UH researcher set to explore how testosterone works in the brain

Most people have some idea about the hormone testosterone –how it regulates male behavior or how too little of it might cause a decrease in libido and too much might cause aggressive and irritable behavior. Turns out, no one yet knows how testosterone really does all that.

16 Aug 2021

Combining inhibitor drug with immunotherapy agent improves response in cancer patients

Combining a histone deacetylase inhibitor drug with immunotherapy agents is safe, and may benefit some patients with advanced cancers that have not responded to traditional therapy, according to results of a phase 1 clinical trial led by researchers at the Johns Hopkins Kimmel Cancer Center, Bloomberg~Kimmel Institute for Cancer Immunotherapy and several other centers including University of Pittsburgh Cancer Institute, Yale Cancer Center and City of Hope in Los Angeles, which participated in study enrollment, and the University of Southern California and University College Cork in Ireland, which collaborated on analysis of the data.

16 Aug 2021

Penn researchers reveal complex details of T-cell responses to mRNA COVID-19 vaccines

Messenger-RNA (mRNA) vaccines against the coronavirus that causes COVID-19 provoke a swift and strong response by the immune system's T cells - the heavy armor of the immune system - according to a study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

16 Aug 2021

Understanding how to regulate key enzyme may lead to new treatments for cancers, viral infections

A new study led by University of California, Irvine (UCI) researchers identifies two ways in which APOBEC3A - a vital enzyme that is responsible for genetic changes resulting in a variety of cancers while protecting our cells against viral infection - is controlled.

13 Aug 2021

UC Davis joins with Pfizer for COVID-19 booster vaccine trial

As COVID-19 booster shots begin for those with compromised immune systems, researchers at the UC Davis School of Medicine continue to collect data from clinical trial participants.

13 Aug 2021

Nanotechnology may help improve treatment for colorectal cancer and melanoma

University of Arizona Health Sciences researchers recently completed a study that has the potential to improve cancer treatment for colorectal cancer and melanoma by using nanotechnology to deliver chemotherapy in a way that makes it more effective against aggressive tumors.

12 Aug 2021

Study identifies Foxo1 gene as a potential treatment target for hereditary lymphedema

A University of South Florida preclinical study unexpectedly identified the gene Foxo1 as a potential treatment target for hereditary lymphedema.

10 Aug 2021

New approach could be a useful tool in the fight against cancer drug resistance

Using a virus to purposely mutate genes that produce cancer-driving proteins could shed light on the resistance that inevitably develops to cancer drugs that target them, a new study led by UT Southwestern scientists suggests.

10 Aug 2021

Study offers new insights on coronary microvascular dysfunction

New research has shown abnormalities in the tiny blood vessels of human hearts in regions well beyond the large arteries with atherosclerotic blockages that trigger the need for stents or bypass surgery.

9 Aug 2021

Injuries mount as sales reps for device makers cozy up to surgeons, even in operating rooms

Cristina Martinez's spinal operation in Houston was expected to be routine. But after destabilizing her spine, the surgeon discovered the implant he was ready to put in her back was larger than he wanted to use — and the device company’s sales rep didn’t have a smaller size on hand, according to a report he filed about the operation.

9 Aug 2021

Researchers identify genetic markers linked to COVID-19 severity and susceptibility

In collaboration with Northwestern Medicine investigators, an international multi-center study has identified genetic factors associated with SARS-CoV-2 infection and COVID-19 severity, according to findings published in Nature.

6 Aug 2021

Researchers develop a new way to detect placenta accreta spectrum disorder during pregnancy

Researchers from UCLA and Cedars-Sinai have developed a new way to detect a potentially life-threatening condition that can occur during pregnancy.

3 Aug 2021

Study looks at potent phytocompounds from Himalayan herbs to treat COVID-19

Considering the antiviral activity of medicinal herbs, a new study published in the journal Current Pharmacology Reports focuses on the identification of potent phytochemicals from Himalayan herbs, namely, Rheum emodi, Thymus serpyllum, and Artemisia annua, for the treatment of COVID-19.

1 Aug 2021

UVA researchers overturn conventional wisdom on action of key hormone receptors within cells

Researchers at the University of Virginia School of Medicine have overturned conventional wisdom on the workings of vital hormone receptors within cells, a finding that could boost drug development for diabetes and related metabolic disorders, cancer and other diseases.

31 Jul 2021

UT Southwestern discovers the Achilles’ heel in ovarian cancers and potential biomarkers

UT Southwestern faculty have discovered what appears to be an Achilles' heel in ovarian cancers, as well as new biomarkers that could point to which patients are the best candidates for possible new treatments.

30 Jul 2021

Analysis of DNA tags could advance the understanding and treatment of many cancers

Cell-free DNA (cfDNA) shed into the blood was discovered in the late 1940s but with rapid advances in genomics and computational analytics in just the past few years, researchers at Georgetown Lombardi Comprehensive Cancer Center now believe that studying tags, or modifications to this type of DNA, may lead to a better understanding of how to assess, and possibly modulate, treatment approaches for cancer and other diseases.

27 Jul 2021

Facing headwinds on new Alzheimer’s drug, Biogen launches controversial campaign

Do you sometimes lose your train of thought or feel a bit more anxious than is typical for you?

23 Jul 2021

Research provides new insight into uncontrolled inflammation in COVID-19 patients

Research led by Queen Mary University of London provides new insight into the mechanisms that lead to uncontrolled inflammation in COVID-19 patients.

22 Jul 2021

Study reveals calcium's role in directing blood flow in the brain

Unlike the rest of the body, there is not enough real estate in the brain for stored energy. Instead, the brain relies on the hundreds of miles of blood vessels within it to supply fresh energy via the blood. Yet, how the brain expresses a need for more energy during increased activity and then directs its blood supply to specific hot spots was, until now, poorly understood.

22 Jul 2021

Pharmacology News and Research

Latest Pharmacology News and Research

Designing antimalarials with multiple targeting mechanisms of action

UH researcher set to explore how testosterone works in the brain

Combining inhibitor drug with immunotherapy agent improves response in cancer patients

Penn researchers reveal complex details of T-cell responses to mRNA COVID-19 vaccines

Understanding how to regulate key enzyme may lead to new treatments for cancers, viral infections

UC Davis joins with Pfizer for COVID-19 booster vaccine trial

Nanotechnology may help improve treatment for colorectal cancer and melanoma

Study identifies Foxo1 gene as a potential treatment target for hereditary lymphedema

New approach could be a useful tool in the fight against cancer drug resistance

Study offers new insights on coronary microvascular dysfunction

Injuries mount as sales reps for device makers cozy up to surgeons, even in operating rooms

Researchers identify genetic markers linked to COVID-19 severity and susceptibility

Researchers develop a new way to detect placenta accreta spectrum disorder during pregnancy

Study looks at potent phytocompounds from Himalayan herbs to treat COVID-19

UVA researchers overturn conventional wisdom on action of key hormone receptors within cells

UT Southwestern discovers the Achilles’ heel in ovarian cancers and potential biomarkers

Analysis of DNA tags could advance the understanding and treatment of many cancers

Facing headwinds on new Alzheimer’s drug, Biogen launches controversial campaign

Research provides new insight into uncontrolled inflammation in COVID-19 patients

Study reveals calcium's role in directing blood flow in the brain

Pittcon Highlights: Pharmaceutical & Biologic eBook

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Scalable, Smart, and Accessible: The Future of Lab Automation

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Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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