Pharmacology News and Research

Latest Pharmacology News and Research

New modeling approach to better understand how tumors become aggressive

Although the development of secondary cancerous growths, called metastasis, is the primary cause of death in most cancers, the cellular changes that drive it are poorly understood.

29 Mar 2021

Major CIHR grant to help find and tackle the root cause of neurodegenerative disease

Dr. Simonetta Sipione, GlycoNet Investigator and Professor in the Department of Pharmacology at the University of Alberta, was recently awarded a major five-year grant from the Canadian Institutes of Health Research, worth $1.04 million.

26 Mar 2021

Lupus patients with lower vitamin D levels more likely to have metabolic syndrome, insulin resistance

Patients with lupus are more likely to have metabolic syndrome and insulin resistance - both factors linked to heart disease - if they have lower vitamin D levels, a new study reveals.

26 Mar 2021

The pressure is on to diagnose and treat chronic kidney disease

In this interview, Helen Yeh, the Vice President, Biopharmaceuticals Medical, Cardiovascular, Renal and Metablosim at AstraZeneca , talks News-Medical to about chronic kidney diseas (CKD).

From AstraZeneca 26 Mar 2021

UArizona researcher finds a unique approach to tackle both Alzheimer’s disease and diabetes

A University of Arizona Health Sciences researcher examined the role of cholesterol in both Alzheimer's disease and Type 2 diabetes to identify a small molecule that may help regulate cholesterol levels in the brain, making it a potential new therapeutic target for Alzheimer's disease.

25 Mar 2021

UCLA researchers receive NIH grants to identify new ways to treat pancreatic cancer

A team of researchers from the UCLA Jonsson Comprehensive Cancer Center has been awarded two research grants totaling $6 million from the National Institutes of Health to identify new ways to treat pancreatic cancer.

25 Mar 2021

Persistent loneliness during midlife can increase risk of dementia, Alzheimer’s disease

Being persistently lonely during midlife (ages 45-64) appears to make people more likely to develop dementia and Alzheimer's Disease (AD) later in life. However, people who recover from loneliness, appear to be less likely to suffer from dementia, compared to people who have never felt lonely.

24 Mar 2021

Speakers Announced for Virtual Experimental Biology 2021 Meeting

Renowned scientists—including Nobel laureates, research pioneers, and celebrated educators—will speak at the virtual Experimental Biology (EB) 2021 meeting, to be held April 27–30.

23 Mar 2021

New research could help predict acute reactions to psychedelic drugs

As psychedelics gain ground as a potential therapy for mental health disorders, there remains a pressing concern that patients in clinical trials may have adverse effects to the drugs.

22 Mar 2021

New book explains the functional aspects of melanogenesis and related disorders

The Vertebrate Pigmentary System: From pigment cells to disorders provides readers with fundamental knowledge of the structural and functional aspects of vertebrate pigment cells - melanophores and melanocytes - from their origin to different stages of development to related diseases.

22 Mar 2021

Pancreatic cancer cells use adaptive mechanisms to avoid death by starvation

In new findings published online March 18, 2021 in the journal Cancer Cell, an international team of researchers, led by scientists at University of California San Diego School of Medicine and Moores Cancer Center, describe how pancreatic cancer cells use an alternative method to find necessary nutrients, defying current therapies, to help them grow and spread.

19 Mar 2021

Specific neurons release dopamine to regulate pain differently in male and female mice

Males and females, generally speaking, experience and respond to pain differently, but scientists have yet to understand all the brain circuits involved in these differences.

19 Mar 2021

Scientists explore structure of SARS-CoV-2 receptor-binding domain with G485R mutation

Researchers at the Bio21 Institute and Department of Biochemistry and Pharmacology, The University of Melbourne, studied the structure of a SARS-CoV-2 spike receptor-binding domain (RBD) with a G485R mutation. This mutation is a residue and not directly involved in interactions with the angiotensin-converting enzyme 2 (ACE2) residues but found in the Β1´/Β2' loop region.

18 Mar 2021

Amino acids signaling controls whole-body glucose homeostasis, study shows

Amino acids are a major nutrient type for humans and are used as building blocks and a source of energy for cells.

16 Mar 2021

Researchers find no evidence to suggest a link between beta blockers and depression

Drugs such as beta-adrenergic antagonists (beta blockers) have been linked to a range of adverse effects, including depression.

15 Mar 2021

Immuno-PET detects changes in different cancer receptors in response to targeted therapies

Immuno-positron emission tomography (PET) imaging can provide early insight into a tumor's response to targeted therapy, allowing physicians to select the most effective treatment for patients who have cancer.

13 Mar 2021

Overexpression of signaling protein in heart associated with poor survival after heart attack

About 6.2 million Americans suffer from heart failure, an incurable disease with a staggering mortality rate - some 40 percent of patients die within five years of diagnosis. Heart failure is one form of heart disease, for which new therapies are desperately needed.

13 Mar 2021

New book provides general introduction about COVID-19, history, and diagnosis

Recently, a novel coronavirus (2019-nCoV) emerged in China and rapidly spread worldwide. It is declared an ongoing outbreak as a global public health emergency by the World Health Organization (WHO).

12 Mar 2021

New brain sensor could transform our understanding of Alzheimer’s

Scientists at the University of Virginia School of Medicine have developed a tool to monitor communications within the brain in a way never before possible, and it has already offered an explanation for why Alzheimer's drugs have limited effectiveness and why patients get much worse after going off of them.

9 Mar 2021

Scientists develop RNA-based therapeutic strategy for Charcot-Marie Tooth disease

Charcot-Marie Tooth disease is the most common hereditary neurological disease in the world. It affects the peripheral nerves and causes progressive paralysis of the legs and hands.

9 Mar 2021

Pharmacology News and Research

Latest Pharmacology News and Research

New modeling approach to better understand how tumors become aggressive

Major CIHR grant to help find and tackle the root cause of neurodegenerative disease

Lupus patients with lower vitamin D levels more likely to have metabolic syndrome, insulin resistance

The pressure is on to diagnose and treat chronic kidney disease

UArizona researcher finds a unique approach to tackle both Alzheimer’s disease and diabetes

UCLA researchers receive NIH grants to identify new ways to treat pancreatic cancer

Persistent loneliness during midlife can increase risk of dementia, Alzheimer’s disease

Speakers Announced for Virtual Experimental Biology 2021 Meeting

New research could help predict acute reactions to psychedelic drugs

New book explains the functional aspects of melanogenesis and related disorders

Pancreatic cancer cells use adaptive mechanisms to avoid death by starvation

Specific neurons release dopamine to regulate pain differently in male and female mice

Scientists explore structure of SARS-CoV-2 receptor-binding domain with G485R mutation

Amino acids signaling controls whole-body glucose homeostasis, study shows

Researchers find no evidence to suggest a link between beta blockers and depression

Immuno-PET detects changes in different cancer receptors in response to targeted therapies

Overexpression of signaling protein in heart associated with poor survival after heart attack

New book provides general introduction about COVID-19, history, and diagnosis

New brain sensor could transform our understanding of Alzheimer’s

Scientists develop RNA-based therapeutic strategy for Charcot-Marie Tooth disease

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Pharmacology News and Research

Latest Pharmacology News and Research

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How can microdialysis benefit drug development

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