Pneumonia News and Research

Latest Pneumonia News and Research

Pandemic of antibiotic resistance is shortening the lives of children in Bangladesh

Resistance to antibiotics is common and often deadly among children with pneumonia in Bangladesh, according to a new study coauthored by researchers from Massachusetts General Hospital (MGH) with colleagues at the International Centre for Diarrhoeal Disease Research, Bangladesh (abbreviated as icddr,b).

15 Jul 2021

Diagnosis and management of COVID-19 in clinical settings

The coronavirus disease 2019 (COVID-19) outbreak has spread throughout the globe and much time has passed since it was declared as a pandemic by the World Health Organization (WHO).

14 Jul 2021

Could corticosteroids increase mortality in COVID-19 patients without high oxygen supplementation?

A new paper focuses on the role of corticosteroids, in particular, as these were widely used among patients on intensive respiratory support (IRS).

14 Jul 2021

SARS-CoV-2 variants show distinct humoral response and transcriptional profiles in hamster model

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel, highly infectious respiratory virus, and the causative agent of coronavirus disease 2019 (COVID-19) pandemic. SARS-CoV-2, which first originated in Wuhan, in Hubei province of China, is a member of the Coronavirdae family and has a large, non-segmented RNA genome.

14 Jul 2021

Blood test could be a simple and effective method for monitoring SARS-CoV-2 infection

A blood test that quantifies the protein ACE2, the cellular protein which allows entry of the coronavirus into cells, as well as ACE2 fragments, produced as a result of interaction with the virus, could be a simple and effective method for monitoring SARS-CoV-2 infection, according to a study led by Javier Sáez-Valero, from the UMH-CSIC Neurosciences Institute in Alicante, published in FASEB Journal.

13 Jul 2021

GARDP, CHAI and Shionogi collaborate to accelerate access to antibiotic for bacterial infections

The Global Antibiotic Research and Development Partnership, the Clinton Health Access Initiative and Shionogi & Co., Ltd today announced a Memorandum of Understanding to accelerate access, including in low- and middle-income countries, to the antibiotic cefiderocol for bacterial infections in patients with limited treatment options.

13 Jul 2021

Millions of COVID-19 cases went undetected in the first six months of the pandemic, finds study

A new report published in the journal Science Translational Medicine estimates that potentially 16.8 million Americans were infected but not officially diagnosed with SARS-CoV-2 by July 2020. In addition, the results suggest there were nearly five undetected coronavirus cases for every diagnosed coronavirus infection in the first six months of the pandemic.

12 Jul 2021

Review of scientific evidence supports zoonotic origin for SARS-CoV-2 with zero biological evidence for laboratory leak scenario

Recently, an international team of biologists, led by professors from the University of Sydney and the University of Edinburgh, critically reviewed currently available scientific evidence that may throw some light on the origin of the virus that causes COVID-19.

12 Jul 2021

Composition and structure of nasopharyngeal microbiome relate to COVID-19 disease severity

Breathing treatments are provided to hospitalized COVID-19 patients. In this study, the researchers examined the community composition in relation to three attributes - COVID-19 status, breathing assistance, and antibiotic use. This study is published in the journal, Applied Microbiology.

12 Jul 2021

Can memory T cell responses to seasonal coronaviruses protect against severe COVID-19?

In a recent study published in the journal Science Immunology, scientists have revealed that the presence of CD8+ T cells against conserved epitopes of seasonal coronaviruses is associated with mild coronavirus disease 2019 (COVID-19). These immune cells exhibit a memory phenotype and provide protection against severe disease.

7 Jul 2021

Investigation reveals considerable added benefit of remdesivir for moderately ill COVID-19 patients

Since July 2020, remdesivir has been conditionally approved in Europe for the treatment of coronavirus disease (COVID-19) in adults and adolescents aged 12 years and older with pneumonia who require supplemental oxygen but no invasive ventilation.

6 Jul 2021

Study explores the effects of SARS-CoV-2 (and other betacoronaviruses) on cellular mRNA processing

A new study has been released on the bioRxiv* preprint server, which deals with a comprehensive survey on alternative splicing concerning SARS-CoV-2 infection. This study has also included two other betacoronavirurses (SARS-CoV and MERS), a control set of unrelated viruses, and a bacterium, namely, Streptococcus pneumonia. The study findings suggest that several cellular parameters are affected owing to a betacoronavirus infection, which in turn affects some genes and invariably various biological functions.

6 Jul 2021

Antibiotic clofoctol shows potential against SARS-CoV-2

In a recent study, a group of French researchers aimed to reduce the regulatory preclinical development steps that potential candidates are normally subjected to.

5 Jul 2021

New clinical and prognostic characteristics discovered in solid organ recipients with COVID-19

Researchers from 12 Spanish hospitals took part with the aim of uncovering clinical and prognostic characteristics in solid organ recipients with COVID-19. The conclusions underscore the need for strict preventive measures in the initial period after transplantation.

2 Jul 2021

Stool transplant may be worth exploring as treatment option for COVID-19

It might be worth exploring stool transplant to treat COVID-19 infection, suggest doctors in a letter published online in the journal Gut, after they used the procedure in two patients to prevent the recurrence of another bacterial infection.

2 Jul 2021

Study highlights the importance of T cell cross reactivity in stopping severe COVID-19 infections

Researchers at La Jolla Institute for Immunology have found that T cells from people who have recovered from COVID-19 or received the Moderna or Pfizer-BioNTech vaccines are still able to recognize several concerning SARS-CoV-2 variants.

1 Jul 2021

How does dexamethasone therapy work in severe COVID-19?

The possible mechanisms that result in dexamethasone being an effective drug against severe SARS-CoV-2 infection are investigated in a new study. The paper’s authors advance the hypothesis that SARS-CoV-2 infection induces cell-specific insensitivity to glucocorticoids, possibly as an unintentional result of the viral replication cycle.

29 Jun 2021

Transfer learning technique achieves 99.24% success when detecting COVID-19 in chest x-rays

Results of this technique, known as transfer learning, achieved a 99.24 per cent success rate when detecting COVID-19 in chest x-rays.

28 Jun 2021

Could the activation of FcγRIII/CD16 by anti-spike SARS-CoV-2 antibodies independently determine COVID-19 severity?

A team of scientists from Germany recently investigated whether hyperactivation of immune receptors that recognize the Fc part of an IgG molecule (FcγR) can lead to immunopathologic changes in coronavirus disease 2019 (COVID-19) patients. They have observed that hyperactivation of FcγRIII (CD16) by proinflammatory IgG antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can significantly contribute to COVID-19 related immunopathology.

28 Jun 2021

Tocilizumab and sarilumab shown to be effective in critical COVID-19

A new study, released as a preprint on the medRxiv* server, describes how a team of researchers from the University Medical Center Utrecht in the Netherlands explored the efficacy of four monoclonal antibodies that antagonize powerful pro-inflammatory pathways. The team sought to determine which were useful in treating critically ill COVID-19 patients on organ support.

28 Jun 2021

Pneumonia News and Research

Latest Pneumonia News and Research

Pandemic of antibiotic resistance is shortening the lives of children in Bangladesh

Diagnosis and management of COVID-19 in clinical settings

Could corticosteroids increase mortality in COVID-19 patients without high oxygen supplementation?

SARS-CoV-2 variants show distinct humoral response and transcriptional profiles in hamster model

Blood test could be a simple and effective method for monitoring SARS-CoV-2 infection

GARDP, CHAI and Shionogi collaborate to accelerate access to antibiotic for bacterial infections

Millions of COVID-19 cases went undetected in the first six months of the pandemic, finds study

Review of scientific evidence supports zoonotic origin for SARS-CoV-2 with zero biological evidence for laboratory leak scenario

Composition and structure of nasopharyngeal microbiome relate to COVID-19 disease severity

Can memory T cell responses to seasonal coronaviruses protect against severe COVID-19?

Investigation reveals considerable added benefit of remdesivir for moderately ill COVID-19 patients

Study explores the effects of SARS-CoV-2 (and other betacoronaviruses) on cellular mRNA processing

Antibiotic clofoctol shows potential against SARS-CoV-2

New clinical and prognostic characteristics discovered in solid organ recipients with COVID-19

Stool transplant may be worth exploring as treatment option for COVID-19

Study highlights the importance of T cell cross reactivity in stopping severe COVID-19 infections

How does dexamethasone therapy work in severe COVID-19?

Transfer learning technique achieves 99.24% success when detecting COVID-19 in chest x-rays

Could the activation of FcγRIII/CD16 by anti-spike SARS-CoV-2 antibodies independently determine COVID-19 severity?

Tocilizumab and sarilumab shown to be effective in critical COVID-19

Innovation in neuroscience drug discovery - eBook eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

Pneumonia News and Research

Latest Pneumonia News and Research

Innovation in neuroscience drug discovery - eBook eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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