Sepsis News and Research

Latest Sepsis News and Research

Exuberant activation of immune cells in severe COVID-19 resembles lupus

In severe cases of COVID-19, Emory researchers have been observing an exuberant activation of immune cells, resembling acute flares of systemic lupus erythematosus (SLE), an autoimmune disease.

9 Oct 2020

Vitamin D deficiency may predict COVID-19 seroconversion

A recent study published on the preprint server medRxiv* in October 2020 reports the potential contribution of vitamin D deficiency to an increased risk of COVID-19 in a subset of health care workers in the UK.

8 Oct 2020

Rapid, low-cost test for potential universal COVID-19 monitoring

An international team of researchers has presented a convenient, low-cost serology test to detect antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could potentially be made available universally.

7 Oct 2020

Pregnant women who underwent surgery for complicated appendicitis have significantly better outcomes

Pregnant women who underwent immediate surgery to treat a ruptured or abscessed appendix and their fetuses had significantly better outcomes than those whose condition was managed without an operation.

5 Oct 2020

Scientists discover bacteria linked to post-infectious hydrocephalus in infants

Scientists at the Center for Infection and Immunity at Columbia University Mailman School of Public Health have discovered bacteria linked to post-infectious hydrocephalus (PIH), the most common cause of pediatric hydrocephalus worldwide.

30 Sep 2020

Seniors the optimal target for SARS-CoV-2 vaccination

ith several vaccines already in stage 3 clinical trials, a study by University of Warwick researchers and published on the preprint server medRxiv in September 2020 discusses the use of computer modeling techniques in order to achieve optimal vaccine coverage.

28 Sep 2020

Study reveals the differences in non-COVID-19 hospital admissions during rebound period

While declines in U.S. hospital admissions during the onset of COVID-19 has been well-documented, little is known about how admissions during the rebound varied by age, insurance coverage and socioeconomic groups.

26 Sep 2020

LOX-1-immature neutrophils may help identify COVID-19 patients at risk of thrombosis complication

To predict severe outcome in COVID-19 patients, innate immune cellular signals are analyzed, identifying two novel neutrophil subsets: LOX-1- and CD123-expressing CD10-CD64+. Thromboembolic events correlated with high LOX-1 immature neutrophils – a potential prognostic signature.

17 Sep 2020

Simple online tool predicts rehospitalization and death risks for sepsis survivors

A tool to predict the risk of readmission to hospital or death in the first year after leaving hospital for adult survivors of sepsis has been developed by a researcher at King’s.

15 Sep 2020

Earlier treatment with steroids reduces adverse outcomes in patients with septic shock

Some critically ill patients with septic shock need medications called vasopressors to correct dangerously low blood pressure.

14 Sep 2020

Study shows role of pathogens in shaping human evolution

Every human cell harbors its own defenses against microbial invaders, relying on strategies that date back to some of the earliest events in the history of life, researchers report.

10 Sep 2020

Risk stratification tool for COVID-19 patients developed

Researchers have worked on the development of a protocol that could stratify COVID-19 patients based on a scoring system. This new study describing the scoring system for risk stratification is titled, “Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score,” and is published in the latest issue of the British Medical Journal.

9 Sep 2020

COVID-19 pandemic has caused major disruptions to child and maternal health services, show surveys

With the number of under-five deaths at an all-time recorded low of 5.2 million in 2019, disruptions in child and maternal health services due to the COVID-19 pandemic are putting millions of additional lives at stake

9 Sep 2020

Convalescent plasma could be an effective treatment for children with COVID-19

Early findings from researchers at Children's Hospital of Philadelphia (CHOP) show that convalescent plasma appears to be a safe and possibly effective treatment for children with life-threatening cases of COVID-19.

9 Sep 2020

Study addresses the role of macrophage activation syndrome in COVID-19

Scientists review macrophage activation syndrome — a feature of the cytokine storm that kills patients with severe cases of COVID-19, as well as possible treatments.

8 Sep 2020

CRISPR-based system suppresses genes related to AAV antibody production

Gene therapy generally relies on viruses, such as adeno-associated virus (AAV), to deliver genes into a cell. In the case of CRISPR-based gene therapies, molecular scissors can then snip out a defective gene, add in a missing sequence or enact a temporary change in its expression, but the body's immune response to AAV can thwart the whole endeavor.

4 Sep 2020

New method offers hope to patients in critical need of kidney transplant

Kidneys from deceased donors with hepatitis C virus (HCV) infection can be safely transplanted into noninfected recipients when a regimen of direct-acting antiviral therapies is initiated as early as two days after the transplant, according to a study from Massachusetts General Hospital (MGH).

2 Sep 2020