Sepsis News and Research

Latest Sepsis News and Research

Pfizer announces PALOMA-3 trial results in patients with HR+, HER2- metastatic breast cancer

Pfizer Inc. today announced detailed overall survival data from the PALOMA-3 trial, which evaluated IBRANCE (palbociclib) in combination with fulvestrant compared to placebo plus fulvestrant in women with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer whose disease progressed on or after prior endocrine therapy.

22 Oct 2018

Exelixis presents CABOSUN and METEOR trial results in patients with advanced renal cell carcinoma

Exelixis, Inc. today announced results from two analyses evaluating the effect of PD-L1 expression or prior treatment with immune checkpoint inhibitors on the efficacy of cabozantinib in patients with advanced renal cell carcinoma (RCC). The findings are being presented this week at the European Society for Medical Oncology 2018 Congress being held October 19-23 in Munich, Germany.

22 Oct 2018

Mice study shows antibiotics are not always necessary to cure sepsis

Biochemists, microbiologists, drug discovery experts and infectious disease doctors have teamed up in a new study that shows antibiotics are not always necessary to cure sepsis in mice.

17 Oct 2018

Breastfeeding reduces the number of antibiotic-resistant bacteria in infant gut

A new study from the University of Helsinki shows that babies that are breastfed for at least six months have less antibiotic-resistant bacteria in their gut compared with infants breastfed for a shorter time. In addition, antibiotic use by mothers increases the number of antibiotic-resistant bacteria in infants.

15 Oct 2018

Allele awarded NIH grant to develop nanoantibody therapies for treatment of sepsis

The National Institute of General Medical Sciences of NIH has awarded a Small Business Innovative Research grant to Allele Biotechnology and Pharmaceuticals to develop new single-domain nanoantibody therapies for the treatment of sepsis.

15 Oct 2018

Potential 'early warning markers' for sepsis discovered

A multi-site research collaboration supported by a Technology Strategy Board Grant has shown that immune response signatures could be used as an early warning test for the serious condition sepsis in patients attending emergency departments with suspected infection.

15 Oct 2018

Prevalence of virulent K. pneumoniae strains among neonates is higher than was previously thought

The research was conducted by Kazan Federal University, Kazan State Medical University, City Clinical Children's Hospital N 1, and Republican Clinical Infectious Diseases Hospital.

10 Oct 2018

Prenatal inflammation may explain why some infants are more prone to neonatal sepsis

Each year 15 million infants are born preterm and face high risks of short- and long-term complications, including sepsis, severe inflammation of the gut, and neurodevelopmental disorders.

9 Oct 2018

NCCN adds COPIKTRA capsules to NCCN Guidelines for follicular lymphoma

Verastem, Inc., focused on developing and commercializing medicines to improve the survival and quality of life of cancer patients, today announced that the National Comprehensive Cancer Network added COPIKTRA (duvelisib) capsules to the Clinical Practice Guidelines in Oncology (NCCN Guidelines) for follicular lymphoma.

8 Oct 2018

Study identifies risk factors of maternal mortality in mechanically ventilated pregnant patients

Researchers in Columbia, South America, conducted a retrospective observational study within six hospitals to identify risk factors of maternal mortality in mechanically ventilated pregnant patients.

5 Oct 2018

Doctors use bacteriophages to treat patient with multi-drug resistant bacterial infection

The married professors were spending their Thanksgiving holiday in Egypt when the husband, Thomas L. Patterson, Ph.D., got very sick very quickly, experiencing fever, nausea and a racing heartbeat. By the time Patterson was accurately diagnosed with a highly multi-drug resistant bacterial infection, he was near death.

4 Oct 2018

High-quality hospitals provide lower cost care for 82% of diagnoses, analysis reveals

High-quality hospitals deliver lower-cost care for 82% of diagnoses, according to a new analysis that Advisory Board released today on variations in care that do not improve care costs or patient outcomes.

3 Oct 2018

Miniature magnetic swimming devices could deliver drugs to specific areas of body

Scientists have created miniature magnetic swimming devices - which mimic the appearance of sperm cells - that could revolutionize disease treatment by swimming drugs to specific areas of the body.

3 Oct 2018

Penn scientists to explore new approach for predicting and treating diseases at individual level

A new National Institutes of Health High-Risk, High-Reward grant will allow Penn State's Steven Schiff and team to explore a radically changed approach to predicting, preventing and treating infectious disease at the individual level at point-of-care.

3 Oct 2018

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.

1 Oct 2018

Gangrene-causing bacteria show promise as cancer treatment

Researchers have found that the bacteria responsible for causing gangrene could also be used to treat patients with certain cancers.

1 Oct 2018

$Bacterial therapy shows early clinical efficacy in patients with treatment-refractory solid tumors$

Bacterial therapy shows early clinical efficacy in patients with treatment-refractory solid tumors

A phase I clinical trial investigating the use of bacterial Clostridium novyi-NT spores as an injectable monotherapy had manageable toxicities and showed early clinical efficacy in patients with treatment-refractory solid tumor malignancies, according to data presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30-Oct. 3.

30 Sep 2018

Critical illness and major infection can promote brain changes, accelerate cognitive decline

Researchers at Johns Hopkins report that a novel analysis of more than a thousand patients adds to evidence that hospitalization, critical illness and major infection may diminish brain structures that are most commonly affected by Alzheimer's disease.

28 Sep 2018

GARDP partners with Novartis to accelerate development of generic antibiotic treatments for children

The Global Antibiotic Research & Development Partnership and Novartis are joining forces to accelerate the development and availability of generic antibiotic treatments for children in low- and middle-income countries.

27 Sep 2018

Scientists discover most important target of MRSA bacterial toxin and ways to neutralize it

For patients diagnosed with a Staphylococcus aureus infection, often referred to as a staph or MRSA infection, every minute counts.

27 Sep 2018

Sepsis News and Research

Latest Sepsis News and Research

Pfizer announces PALOMA-3 trial results in patients with HR+, HER2- metastatic breast cancer

Exelixis presents CABOSUN and METEOR trial results in patients with advanced renal cell carcinoma

Mice study shows antibiotics are not always necessary to cure sepsis

Breastfeeding reduces the number of antibiotic-resistant bacteria in infant gut

Allele awarded NIH grant to develop nanoantibody therapies for treatment of sepsis

Potential 'early warning markers' for sepsis discovered

Prevalence of virulent K. pneumoniae strains among neonates is higher than was previously thought

Prenatal inflammation may explain why some infants are more prone to neonatal sepsis

NCCN adds COPIKTRA capsules to NCCN Guidelines for follicular lymphoma

Study identifies risk factors of maternal mortality in mechanically ventilated pregnant patients

Doctors use bacteriophages to treat patient with multi-drug resistant bacterial infection

High-quality hospitals provide lower cost care for 82% of diagnoses, analysis reveals

Miniature magnetic swimming devices could deliver drugs to specific areas of body

Penn scientists to explore new approach for predicting and treating diseases at individual level

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Gangrene-causing bacteria show promise as cancer treatment

Bacterial therapy shows early clinical efficacy in patients with treatment-refractory solid tumors

Critical illness and major infection can promote brain changes, accelerate cognitive decline

GARDP partners with Novartis to accelerate development of generic antibiotic treatments for children

Scientists discover most important target of MRSA bacterial toxin and ways to neutralize it

Innovation in neuroscience drug discovery - eBook eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

Sepsis News and Research

Latest Sepsis News and Research

Innovation in neuroscience drug discovery - eBook eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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