Sickle Cell Disease News and Research

Latest Sickle Cell Disease News and Research

For people with sickle cell disease, ERs can mean life-threatening waits

Heather Avant always dresses up when she goes to the emergency room.

17 Oct 2023

Mount Sinai researchers receive NIH grant to compare new treatment options for sickle cell disease

The Mount Sinai Health System has received a $12,180,625 grant from the National Heart, Lung and Blood Institute to compare new treatment options for sickle cell disease and determine which work best for specific patients.

12 Oct 2023

St. Jude Children's researchers better define hyperdiploidy in childhood B-ALL

Hyperdiploidy is a genetic condition observed in cancer cells, where the cells contain more chromosomes than usual.

20 Sep 2023

Stuart Orkin receives the third Elaine Redding Brinster Prize for development of sickle cell disease therapy

For his work discovering the basis for hemoglobin gene switching and applying those insights to develop a therapy for sickle cell disease and other blood diseases, the Institute for Regenerative Medicine at the University of Pennsylvania awarded Stuart Orkin, MD the third Elaine Redding Brinster Prize in Science or Medicine.

15 Sep 2023

A subset of CD8+ T cells can play a protective role against Alzheimer’s disease pathogenesis

Scientists at St. Jude Children’s Research Hospital found that a subset of CD8+ T cells in the brain lessens the activation of microglia and limits disease pathology in a model of Alzheimer’s disease.

8 Sep 2023

Stem cell gene therapy may offer a promising, curative treatment for sickle cell disease

New research published in the New England Journal of Medicine indicates that stem cell gene therapy may offer a promising, curative treatment for the painful, inherited blood disorder sickle cell disease (SCD).

30 Aug 2023

Immune cells present in people months before influenza infection, finds study

St. Jude Children's Research Hospital scientists, in collaboration with the Institute of Environmental Science and Research (ESR) Limited, found that immune cells present in people months before influenza (flu) infection could more accurately predict if an individual would develop symptoms than current methods which primarily rely on antibody levels.

18 Aug 2023

Mutational accessibility: A key driver of viral evolution

The influenza (flu) virus is constantly undergoing a process of evolution and adaptation through acquiring new mutations.

29 Jul 2023

New gene editing approach could revolutionize the treatment of blood disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

27 Jul 2023

Rice bioengineers receive NIH grant for sickle cell disease research

Rice University bioengineer Gang Bao and his team have won a 4-year, $2.6 million grant from the National Institutes of Health to address critical questions surrounding the safety and efficacy of using gene editing to treat sickle cell disease.

18 Jul 2023

Study describes the scope and integration of music therapy program within UH medical centers

A new study from University Hospitals (UH) Connor Whole Health describes the scope and integration of their music therapy program within10 UH medical centers.

14 Jul 2023

Sickle cell disease: A global call to action

Reducing the burden of Sickle Cell Disease (SCD) requires substantial financial and political commitment to improving data-collection, diagnosis, treatment and training - doing so will positively impact the lives of millions of patients and families worldwide - says a new Commission published in The Lancet Haematology journal.

12 Jul 2023

Study shows how glutamine can help or hinder cancer-killing activity

Scientists at St. Jude Children's Research Hospital found immune and tumor cells compete over glutamine, a major nutrient in their local environment, with significant implications for anti-cancer activity.

5 Jul 2023

Base editing shows promise for treating sickle cell disease and beta thalassemia

Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease (SCD) and beta thalassemia.

3 Jul 2023

New study warns of dangers of gene editing in human embryos

Scientists have discovered that the cells of early human embryos are often unable to repair damage to their DNA.

26 Jun 2023

U.S. patent granted for novel tool designed to reliably diagnose and monitor sickle cell disease

In the United States, sickle cell disease affects about 100,000 people and about 2 million Americans carry this genetic mutation.

22 Jun 2023

New base-edited T-cells proven effective to treat lymphoblastic leukemia

Three young patients with relapsed T-cell leukemia have now been treated with base-edited T-cells, as part of a 'bench-to-bedside' collaboration between UCL and Great Ormond Street Hospital for Children (GOSH).

15 Jun 2023

Study provides a more complete picture of sickle cell disease mortality burden

A new study suggests the number of deaths due to sickle cell disease is 11 times higher than what is indicated from mortality data sources alone. Sickle cell disease is not just underdiagnosed, but it also increases risk of infection and of death from conditions like stroke, heart problems, kidney problems, and pregnancy complications.

13 Jun 2023

Damon Runyon and St. Jude announce a new pediatric-focused fellowship

The Damon Runyon Cancer Research Foundation and St. Jude Children's Research Hospital announced a new pediatric-focused fellowship today.

8 Jun 2023

Electronic health records identified as hidden source of bias impacting clinical trials

Results of clinical trials are only as good as the data upon which they rest. This is especially true in terms of diversity -; if most people in a trial are from a certain race or socioeconomic group, then the results may not be broadly applicable.

7 Jun 2023

Sickle Cell Disease News and Research

Latest Sickle Cell Disease News and Research

For people with sickle cell disease, ERs can mean life-threatening waits

Mount Sinai researchers receive NIH grant to compare new treatment options for sickle cell disease

St. Jude Children's researchers better define hyperdiploidy in childhood B-ALL

Stuart Orkin receives the third Elaine Redding Brinster Prize for development of sickle cell disease therapy

A subset of CD8+ T cells can play a protective role against Alzheimer’s disease pathogenesis

Stem cell gene therapy may offer a promising, curative treatment for sickle cell disease

Immune cells present in people months before influenza infection, finds study

Mutational accessibility: A key driver of viral evolution

New gene editing approach could revolutionize the treatment of blood disorders

Rice bioengineers receive NIH grant for sickle cell disease research

Study describes the scope and integration of music therapy program within UH medical centers

Sickle cell disease: A global call to action

Study shows how glutamine can help or hinder cancer-killing activity

Base editing shows promise for treating sickle cell disease and beta thalassemia

New study warns of dangers of gene editing in human embryos

U.S. patent granted for novel tool designed to reliably diagnose and monitor sickle cell disease

New base-edited T-cells proven effective to treat lymphoblastic leukemia

Study provides a more complete picture of sickle cell disease mortality burden

Damon Runyon and St. Jude announce a new pediatric-focused fellowship

Electronic health records identified as hidden source of bias impacting clinical trials

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Sickle Cell Disease News and Research

Latest Sickle Cell Disease News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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