Sickle Cell Disease News and Research

Latest Sickle Cell Disease News and Research

St. Jude researchers discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Infections and other diseases can cause red blood cells to rupture, releasing the oxygen-binding molecule hemoglobin, which breaks down into heme.

1 Jun 2023

Genetic change supercharged spread and severity of epizootic H5N1 avian influenza virus

St. Jude Children's Research Hospital scientists discovered how the current epizootic H5N1 avian influenza virus (bird flu) gained new genes and greater virulence as it spread west.

30 May 2023

Scientists study the structure and function of a transporter involved in cancer, immunity

Scientists at St. Jude Children's Research Hospital and the University of Texas Southwestern Medical Center studied the structure and function of a transporter involved in cancer and immunity.

24 May 2023

Targeting the hemoglobin problem in sickle cell disease using a new drug

A class of drugs used for their ability to stop tumor cells from dividing is now under study for their potential to reduce the pain and damage caused by sickle cell disease, investigators report.

11 May 2023

New approach addresses the challenge of directly connecting genetic variants to human traits, health

A major challenge in human genetics is understanding which parts of the genome drive specific traits or contribute to disease risk. This challenge is even greater for genetic variants found in the 98% of the genome that does not encode proteins.

5 May 2023

Neighborhood support may help protect pediatric brain tumor patients from cognitive decline

To gain a clearer understanding of the differences between childhood cancer patients with brain tumors when it comes to the impact of radiation therapy on cognition, scientists at St. Jude Children's Research Hospital studied the effect of their environment.

28 Apr 2023

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

To highlight how far the field of genetics has come, we spoke with Dr. Francis Collins, the leader of the Human Genome Project about his incredible career in genetics.

25 Apr 2023

Clinical trial may set a new 'gold standard' for the treatment of childhood craniopharyngioma

St. Jude Children's Research Hospital is reporting phase 2 clinical trial results treating the brain tumor craniopharyngioma with proton therapy.

19 Apr 2023

Precise genome editing approach can correct mutation that causes sickle cell disease

Scientists at St. Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard showed how prime editing can correct the mutation that causes sickle cell disease in a potentially curative approach.

18 Apr 2023

Combination treatment could improve stem cell transplantation process for multiple myeloma patients

The standard treatment for patients with multiple myeloma often includes stem cell transplantation in which the patient's own stem cells are harvested and stored while the patient receives intensive chemotherapy to kill the cancer.

17 Apr 2023

Sickle cell patients undergoing total knee replacement face higher risk for complications

Patients with sickle cell disease (SCD) who undergo total knee replacement are at higher risk for complications than non-SCD patients, according to a large-scale, retrospective study by researchers from UT Southwestern Medical Center and the University of Calgary.

17 Apr 2023

Childhood cancer survivors maintaining a healthy lifestyle may have lower risk of mortality

A report from the Childhood Cancer Survivor Study provides strong evidence of the importance of a healthy lifestyle for adults who were treated for cancer as children.

5 Apr 2023

St. Jude computational biologists characterize the full spectrum of oncogenic fusions in pediatric cancer

The scientific foundation needed to work on curing a class of cancer-causing mutations is here, in the form of a tool from St. Jude Children's Research Hospital.

5 Apr 2023

Hemex Health awarded $3 million grant to advance commercialization of Gazelle Hb Variant Test for the U.S. market

Hemex Health, a medical diagnostic device company focused on expanding healthcare access to underrepresented patient populations, announced it has been awarded a 3-year, $3 million grant from the National Heart, Lung, and Blood Institute.

29 Mar 2023

Understanding the structure of CFTR could help design more effective therapies for cystic fibrosis

Scientists at St. Jude Children's Research Hospital and Rockefeller University have combined their expertise to gain a better understanding of the cystic fibrosis transmembrane conductance regulator (CFTR).

23 Mar 2023

Study highlights a persistent life expectancy gap among patients living with sickle cell disease

While research has long established disparities in health outcomes among individuals living with sickle cell disease (SCD), few studies have quantified these gaps.

16 Mar 2023

Many individuals living with sickle cell disease still lack access to new pain medications

Sickle cell disease (SCD), a rare chronic, progressive, life-threatening, inherited blood disorder, often affects individuals with chronic pain that can be debilitating to their quality of life.

9 Mar 2023

Landmark discovery provides a new perspective on tissue oxygenation

Cardiovascular medicine, hematology and pulmonary medicine may soon have the first-ever therapies to correct poor tissue oxygenation, a key driver of disease in millions, including peripheral artery disease, sickle cell disease, heart failure, stroke, emphysema and many others.

1 Mar 2023

St. Jude researchers show how drug makers can avoid toxicity and resistance

Scientists at St. Jude Children's Research Hospital have demonstrated how drug makers can avoid two key problems: toxicity and resistance.

28 Feb 2023

Three new language versions of the 'Together by St. Jude' online resource launched

St. Jude Children's Research Hospital today announced the launch of three new language versions of the Together by St. Jude online resource, a free source of information and education for families facing childhood and adolescent cancer.

15 Feb 2023

Sickle Cell Disease News and Research

Latest Sickle Cell Disease News and Research

St. Jude researchers discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Genetic change supercharged spread and severity of epizootic H5N1 avian influenza virus

Scientists study the structure and function of a transporter involved in cancer, immunity

Targeting the hemoglobin problem in sickle cell disease using a new drug

New approach addresses the challenge of directly connecting genetic variants to human traits, health

Neighborhood support may help protect pediatric brain tumor patients from cognitive decline

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

Clinical trial may set a new 'gold standard' for the treatment of childhood craniopharyngioma

Precise genome editing approach can correct mutation that causes sickle cell disease

Combination treatment could improve stem cell transplantation process for multiple myeloma patients

Sickle cell patients undergoing total knee replacement face higher risk for complications

Childhood cancer survivors maintaining a healthy lifestyle may have lower risk of mortality

St. Jude computational biologists characterize the full spectrum of oncogenic fusions in pediatric cancer

Hemex Health awarded $3 million grant to advance commercialization of Gazelle Hb Variant Test for the U.S. market

Understanding the structure of CFTR could help design more effective therapies for cystic fibrosis

Study highlights a persistent life expectancy gap among patients living with sickle cell disease

Many individuals living with sickle cell disease still lack access to new pain medications

Landmark discovery provides a new perspective on tissue oxygenation

St. Jude researchers show how drug makers can avoid toxicity and resistance

Three new language versions of the 'Together by St. Jude' online resource launched

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Sickle Cell Disease News and Research

Latest Sickle Cell Disease News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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