T Cell News and Research

Latest T Cell News and Research

An intranasal COVID-19 vaccine elicits long-lasting immunity against SARS-CoV-2 variants in vivo

A team of scientists from the Washington University School of Medicine and the University of Texas Medical Branch, USA, has recently evaluated the durability and robustness of an adenovirus-vectored, spike-based intranasal COVID-19 vaccine in mice.

11 May 2021

Cerebral organoids provide new insight into role of key enzyme in natural brain development

Like many around the world, the lab of Professor Mriganka Sur in The Picower Institute for Learning and Memory at MIT has embraced the young technology of cerebral organoids, or "minibrains," for studying human brain development in health and disease.

11 May 2021

Researchers design compounds that prevent SARS-CoV-2 entry in human lung cells

Researchers have designed a new class of TMPRSS2 inhibitors that have shown broad antiviral activity against coronaviruses, including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

11 May 2021

Novel 'CopyCatcher' detects when precise copying of genetic information takes place in cells

Researchers at the University of California San Diego have laid the groundwork for a potential new type of gene therapy using novel CRISPR-based techniques.

11 May 2021

Experimental gene therapy successfully treats children born without an immune system

An experimental form of gene therapy developed by a team of researchers from UCLA and Great Ormond Street Hospital in London has successfully treated 48 of 50 children born with a rare and deadly inherited disorder that leaves them without an immune system.

11 May 2021

Case study describes consequences of undetected SARS-CoV-2 infection during mRNA vaccination

Now, a new report describes a case of a coincidental mRNA vaccination and SARS-CoV-2 infection in a 31-year-old doctor, addressing the theoretical considerations for potential risks and further required actions in case more cases appear in the future.

11 May 2021

SARS-CoV-2 UK variant more infectious because of higher viral load

The coronavirus disease 2019 (COVID-19) pandemic was triggered by the uncontrolled spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A year and a half later, the relationship between SARS-CoV-2 viral load and infectiousness remains a matter of scientific debate. Now, a new preprint research paper posted to the bioRxiv server aims to quantify this relationship

11 May 2021

Researchers discover the second possible effective mechanism of remdesivir

The virostatic agent remdesivir was developed to disrupt an important step in the propagation of RNA viruses, to which SARS-CoV-2 also belongs: the reproduction of the virus's own genetic material. This is present as RNA matrices with which the host cell directly produces virus proteins.

11 May 2021

Severe COVID-19 linked to genetic clotting predisposition

Thus, the need to stratify the risk of severe or critical disease in patients presenting with SARS-CoV-2 infection remains a crying necessity. A new preprint research paper posted to the medRxiv server discusses the relationship between severe disease and pre-existing susceptibility to clots and other diseases of the cardiovascular system.

11 May 2021

Machine learning approach helps study human hypothalamus at the single-cell level

Human brain organoids are remarkable platforms for modeling features of human brain development and diseases.

11 May 2021

Single-cell map offers a new immunotherapy target for lung cancer treatment

Researchers at The University of Texas MD Anderson Cancer Center have developed a first-of-its-kind spatial atlas of early-stage lung cancer and surrounding normal lung tissue at single-cell resolution, providing a valuable resource for studying tumor development and identifying new therapeutic targets.

11 May 2021

Key protein helps bacteria that causes Legionnaires' disease to set up house in host cells

Scientists at UT Southwestern have discovered a key protein that helps the bacteria that causes Legionnaires' disease to set up house in the cells of humans and other hosts.

10 May 2021

Machine learning technique detects epigenetic drivers of cancers

Scientists have made major advances in understanding and developing treatments for many cancers by identifying genetic mutations that drive the disease.

10 May 2021

Rice University neurobiologist wins NIH grant to study enteric nervous system development

Rice University neurobiologist Rosa Uribe will be hitting the books for her latest study of the digestive system, but some of the pages in her books are a billion years old.

10 May 2021

Normalizing cholesterol metabolism in microglia alleviates chronic neuropathic pain

Chemotherapy can induce a painful peripheral neuropathy (CIPN), a chronic condition and common adverse effect for cancer patients undergoing treatment.

10 May 2021

CDK inhibitors may boost the effectiveness of immune therapy in metastatic breast cancer

A class of drugs that inhibits breast cancer progression when used with hormonal therapy might also boost the effectiveness of immune therapy in cases of recurrent, metastatic breast cancer, according to a new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

10 May 2021

Researchers study how cancer cells re-organize 3D structure of DNA to ramp up oncogene activity

In cancer, a lot of biology goes awry: Genes mutate, molecular processes change dramatically, and cells proliferate uncontrollably to form entirely new tissues that we call tumors.

10 May 2021

Esophageal cancers turn on ancient viral DNA hidden in our genome

Scientists have discovered that many esophageal cancers turn on ancient viral DNA that was embedded in our genome hundreds of millions of years ago.

10 May 2021

New vaccine shows potential to protect from a variety of coronavirus infections

A potential new vaccine developed by members of the Duke Human Vaccine Institute has proven effective in protecting monkeys and mice from a variety of coronavirus infections -- including SARS-CoV-2 as well as the original SARS-CoV-1 and related bat coronaviruses that could potentially cause the next pandemic.

10 May 2021

Grand Challenge research integrates AI to streamline clinical assessment of breast cancer

Breast cancer has recently overtaken lung cancer to become the most common cancer globally, according to the World Health Organization.

10 May 2021

T Cell News and Research

Latest T Cell News and Research

An intranasal COVID-19 vaccine elicits long-lasting immunity against SARS-CoV-2 variants in vivo

Cerebral organoids provide new insight into role of key enzyme in natural brain development

Researchers design compounds that prevent SARS-CoV-2 entry in human lung cells

Novel 'CopyCatcher' detects when precise copying of genetic information takes place in cells

Experimental gene therapy successfully treats children born without an immune system

Case study describes consequences of undetected SARS-CoV-2 infection during mRNA vaccination

SARS-CoV-2 UK variant more infectious because of higher viral load

Researchers discover the second possible effective mechanism of remdesivir

Severe COVID-19 linked to genetic clotting predisposition

Machine learning approach helps study human hypothalamus at the single-cell level

Single-cell map offers a new immunotherapy target for lung cancer treatment

Key protein helps bacteria that causes Legionnaires' disease to set up house in host cells

Machine learning technique detects epigenetic drivers of cancers

Rice University neurobiologist wins NIH grant to study enteric nervous system development

Normalizing cholesterol metabolism in microglia alleviates chronic neuropathic pain

CDK inhibitors may boost the effectiveness of immune therapy in metastatic breast cancer

Researchers study how cancer cells re-organize 3D structure of DNA to ramp up oncogene activity

Esophageal cancers turn on ancient viral DNA hidden in our genome

New vaccine shows potential to protect from a variety of coronavirus infections

Grand Challenge research integrates AI to streamline clinical assessment of breast cancer

Immunology eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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