T Cell News and Research

Latest T Cell News and Research

Is there an association between exposure to ultrafine particles during pregnancy and influenza infection severity?

Researchers explored the impact of exposure to ultrafine particles during pregnancy on the risk of influenza.

19 Apr 2023

Researchers discover the molecule responsible for guiding T cells toward tumors

Immunotherapy, particularly CAR T-Cell treatment for cancer, is extending the lives of many patients. But sometimes the therapy randomly migrates to places it shouldn't go, tucking into the lungs or other noncancerous tissue and causing toxic side effects.

18 Apr 2023

Tissue-resident memory cells are key to immunity to Salmonella in mice

Salmonella infections cause about a million deaths a year worldwide, and there is an urgent need for better vaccines for both typhoid fever and non-typhoidal Salmonella disease.

18 Apr 2023

Vaccine component BNT162b4 enhances T-cell immunity against SARS-CoV-2 variants for reduced COVID-19 disease severity

Researchers designed a novel messenger ribonucleic acid (mRNA) vaccine component designated BNT162b4.

17 Apr 2023

Pregnant women show unique immune response to COVID-19

Researchers compare the adaptive, innate, and humoral immune responses between pregnant and non-pregnant women with COVID-19.

16 Apr 2023

How SARS-CoV-2 Omicron subvariants have evolved to evade host T-cell immunity

Researchers investigate whether SARS-CoV-2 and its variants have evolved to evade CD8+ T cell-mediated immunity.

15 Apr 2023

AI-designed T-cell vaccine extremely effective at preventing severe COVID-19 in mice

The current COVID-19 vaccines are designed to trigger an antibody response to the SARS-CoV-2 spike protein, which is vulnerable to mutations that could make the vaccine less effective over time.

13 Apr 2023

COVID mRNA vaccines fall short in eliciting lung resident memory T cells compared to natural infection

Pieren, D. K. J., Kuguel, S. G., Rosado, J., Robles, A. G., Rey-Cano, J., Mancebo, C., Esperalba, J., Falcó, V., Buzón, M. J., & Genescà, M. (2023). Limited induction of polyfunctional lung-resident memory T cells against SARS-CoV-2 by mRNA vaccination compared to infection. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-37559-w, https://www.nature.com/articles/s41467-023-37559-w

10 Apr 2023

Study assesses the cellular and molecular immunopathology of post-COVID lung disease

Researchers assessed the cellular and molecular level immunopathology of PCLD.

4 Apr 2023

What is currently known about the mechanisms by which DNA tumor viruses evade uracil-mediated antiviral immunity?

Researchers reviewed the existing knowledge on the mechanisms through which DNA tumor viruses evade the antiviral immunity mediated through mis-incorporated uracil (U).

3 Apr 2023

High consumption of common artificial sweetener lowers activation of T-cells in mice

Scientists at the Francis Crick Institute have found that high consumption of a common artificial sweetener, sucralose, lowers activation of T-cells, an important component of the immune system, in mice.

31 Mar 2023

Utilizing a molecular syringe for the delivery of functional proteins into human cells with high efficiency

Researchers investigated the feasibility of utilizing a bacterial contractile injection system for programmable protein delivery.

31 Mar 2023

CAR T-cell therapy improves quality of life for patients with blood cancers

Chimeric antigen receptor T-cell (CAR-T) therapy has transformed cancer treatment, yet relatively few studies have investigated the impact of the therapy on longitudinal patient quality of life – an aspect of care that often suffers from receiving traditional intensive cancer medications, such as chemotherapy.

30 Mar 2023

$3.2 million grant aids in the study of genetic testing approach to close racial disparity gaps in cancer care

With the aid of a near $3.2 million National Cancer Institute grant (R01CA277599) recently awarded, investigators from the state's leading cancer program, Rutgers Cancer Institute of New Jersey,  and Georgetown University's Lombardi Comprehensive Cancer Center, both NCI-designated Comprehensive Cancer Centers, will work to close racial disparity gaps in cancer care delivery by examining a novel approach to genetic testing and care based on community-identified needs.

30 Mar 2023

The breadth of immune responses following COVID-19 vaccination in hematology patients with diseases and treatments impacting B cell immunity

A study published in Cell Reports Medicine describes that COVID-19 vaccines induce strong T cell response in blood cancer patients, irrespective of antibody response and B cell numbers.

30 Mar 2023

Do two or more mRNA vaccine doses provide additional protection in patients with prior COVID-19 infection?

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T Cell News and Research

Latest T Cell News and Research

Is there an association between exposure to ultrafine particles during pregnancy and influenza infection severity?

Researchers discover the molecule responsible for guiding T cells toward tumors

Tissue-resident memory cells are key to immunity to Salmonella in mice

Vaccine component BNT162b4 enhances T-cell immunity against SARS-CoV-2 variants for reduced COVID-19 disease severity

Pregnant women show unique immune response to COVID-19

How SARS-CoV-2 Omicron subvariants have evolved to evade host T-cell immunity

AI-designed T-cell vaccine extremely effective at preventing severe COVID-19 in mice

COVID mRNA vaccines fall short in eliciting lung resident memory T cells compared to natural infection

Study assesses the cellular and molecular immunopathology of post-COVID lung disease

What is currently known about the mechanisms by which DNA tumor viruses evade uracil-mediated antiviral immunity?

High consumption of common artificial sweetener lowers activation of T-cells in mice

Utilizing a molecular syringe for the delivery of functional proteins into human cells with high efficiency

CAR T-cell therapy improves quality of life for patients with blood cancers

$3.2 million grant aids in the study of genetic testing approach to close racial disparity gaps in cancer care

The breadth of immune responses following COVID-19 vaccination in hematology patients with diseases and treatments impacting B cell immunity

Do two or more mRNA vaccine doses provide additional protection in patients with prior COVID-19 infection?

Diverse subset of T-cell clones plays a role in the antitumor effects of immune checkpoint inhibitors

Next-generation influenza vaccines show greater impact and cost-effectiveness, study suggests

How do viral infections cause autoimmune diseases?

Monocytes may be a stable reservoir of HIV in patients taking antiretroviral therapy

Immunology eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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