Toxicology News and Research

Latest Toxicology News and Research

First-of-its-kind conference on personalized medicine for pediatric patients

The world's leading experts in pediatric pharmacogenomics and personalized medicine are gathering at a first-of-its-kind conference in Kansas City to change the way childhood diseases and illnesses are treated through personalized medicine.

22 Apr 2010

miRNAs may generate new insights on cancer and possible future treatments

Scientists are methodically unlocking the biological processes that lead to cancer, and recent discoveries with microRNAs (miRNAs) are revolutionizing their understanding and leading to clinical trials of potentially effective treatments.

21 Apr 2010

Caliper Life Sciences introduces Quantum FX stand-alone microCT system for preclinical imaging

Caliper Life Sciences, Inc., a leading provider of tools and services for drug discovery, life sciences research and molecular diagnostics, today announced the Quantum FX, a stand-alone microCT system for preclinical imaging. Introduced at the American Association for Cancer Research Annual Meeting 2010, the Quantum FX is a low dose, microCT system that provides researchers with a 3-dimensional anatomical view of disease activity, tumor development and therapeutic response over multiple time points during the course of a study.

19 Apr 2010

Phase II study: Hepatitis C patients receiving ANA598 bid plus SOC attain undetectable levels of virus

Anadys Pharmaceuticals, Inc. announced today that 72% of hepatitis C patients receiving ANA598 400 mg twice daily (bid) plus standard of care achieved undetectable levels of virus at week eight in an ongoing Phase II study, compared to 38% of patients receiving placebo plus SOC.

19 Apr 2010

New p53 knockout rat model improves timelines for carcinogenicity screening

Sigma Life Science, the innovative biological products and services brand of Sigma-Aldrich, today introduced the world's first p53 'knockout' rat model, an important development that is expected to, due to the rat's closer physiological and metabolic similarity to humans, significantly improve timelines for carcinogenicity screening and reduce time to market for therapeutics.

19 Apr 2010

VisEn Medical expands FMT imaging platform

VisEn Medical Inc., a leader in fluorescence imaging solutions from research through medicine, announced today that it has expanded its leading FMT imaging platform with an FMT™ Multi-Species Imaging Module, to extend FMT imaging and related applications into larger preclinical animal models. VisEn also announced that it will be presenting new study results from its recently-launched Cat B 750 FAST™ and Annexin-Vivo™ fluorescence imaging agents at the AACR 101st Annual Meeting.

16 Apr 2010

TruthAboutGardasil.org: Governments need to suspend HPV vaccinations/programs

The global outrage at reports of injustices inflicted on the children of India from unethical trials and experimentation of HPV vaccines in socially disadvantaged groups extends to women and children worldwide subjected to similar violations.

16 Apr 2010

InterMune reports Phase 1b MAD study results of RTV-boosted danoprevir in HCV patients at 45th EASL

InterMune, Inc. today announced results of all three cohorts from a 15-day Phase 1b multiple-ascending-dose (MAD) study of low doses of danoprevir (also known as RG7227 and ITMN-191) boosted by low-dose ritonavir (RTV) in patients chronically infected with hepatitis C virus (HCV) genotype-1.

16 Apr 2010

Study: Circadian’s anti-cancer therapy reduces tumour growth in animal models

Circadian Technologies Limited today released data demonstrating that its lead anti-cancer therapeutic, VGX-100, significantly inhibits tumour growth in a variety of different animal models (tumour xenografts) of human cancer.

16 Apr 2010

Cequent Pharmaceuticals commences toxicology study of CEQ508 tkRNAi-based therapeutic candidate

Cequent Pharmaceuticals, a pioneer in the development of novel products to deliver RNAi-based treatments to prevent and treat human disease, has initiated a long-term (26-week) toxicology study of CEQ508 – the company's lead drug candidate based on its proprietary tkRNAi technology. This study is designed to enable a Phase II clinical trial slated for 2011. CEQ508 targets beta-catenin, a key oncogene implicated in the formation of colonic polyps and in the progression of polyps to colorectal cancer.

16 Apr 2010

UALR researcher receives federal grant to track estrogen-mimicking compounds in consumer products

Dr. Jerry Darsey, professor of chemistry in UALR's College of Science and Mathematics, has received $77,000 from a federal Food and Drug Administration grant to develop methods to track estrogen mimicking compounds in various products and assess how use of the products affect women.

16 Apr 2010

3M Drug Delivery Systems grows its product portfolio in Asia’s pharmaceutical industry

3M Drug Delivery Systems recently advanced its participation in the Asian market with a sponsorship of the Asia Pharma R&D Leaders 2010 event, held March 4 and 5 in Shanghai, China.

16 Apr 2010

Current screening methods for FOBT are often not appropriate

More than 75 percent of primary care physicians in the United States who order or perform the fecal occult blood test as a screening option for colorectal cancer perform an in-office test rather than relying on the home-based test, even though the home-based test is more accurate, a study by the Centers for Disease Control and Prevention has found.

16 Apr 2010

UA Superfund Research Program to study contaminated dust, water and health issues

Metal-laden dust and contaminated water, and their health effects, will be the focus of multiple projects for the University of Arizona's Superfund Research Program during the next five years. The National Institutes of Environmental Health Sciences recently notified UA that the Superfund Research Program, funded since 1989, will receive an additional $14 million in grant funding through 2015 to conduct the research.

15 Apr 2010

Dual evacuation following noxious gas leak

According to the Public Services Association there has been a constant leak of noxious fumes from a Newcastle office building for years and the source needs to be identified. The building has RTA call centre staff and Commonwealth Bank customer service representatives as its tenants.

14 Apr 2010

Researchers may be one step closer to slowing the progression of Alzheimer's disease

Researchers may be one step closer to slowing the onset and progression of Alzheimer's disease. An animal study supported by the National Institute of Environmental Health Sciences, part of the National Institutes of Health, shows that by targeting the blood-brain barrier, researchers are able to slow the accumulation of a protein associated with the progression of the illness.

13 Apr 2010

NIAID funds second study of Aeolus Pharmaceuticals' AEOL 10150 as potential countermeasure to GI-ARS

Aeolus Pharmaceuticals, Inc. announced today that a second study of its lead drug, AEOL 10150, has been initiated by the National Institutes of Health's (NIH), National Institute of Allergy and Infectious Diseases (NIAID) Radiation/Nuclear Medical Countermeasures development program as a countermeasure for radiation exposure to the gastrointestinal (GI) tract.

13 Apr 2010

Hunter Valley cancer cluster report to be made public

Cancer cases may have manifested as brain tumors in the local population in Upper Hunter Valley as a result of pollution from mines and power stations. With five residents in a single block in Singleton being diagnosed with brain tumors a public inquiry to establish just how harmful dust and toxins from the mines and power stations are had been constituted by the state government.

13 Apr 2010

Triclosan antibacterial found in soap in the spotlight

If a chemical is banned in other countries and by the European Union, it does merit a study by the FDA, even if there is no existing study to suggest that it is harmful to humans. While there may be no current evidence available that triclosan is hazardous to humans, it has been linked to hormone alterations in animals.

9 Apr 2010

Potential toxicity of zinc nanoparticles in sunscreen products

Scientists are reporting that particle size affects the toxicity of zinc oxide, a material widely used in sunscreens. Particles smaller than 100 nanometers are slightly more toxic to colon cells than conventional zinc oxide. Solid zinc oxide was more toxic than equivalent amounts of soluble zinc, and direct particle to cell contact was required to cause cell death. Their study is in ACS' Chemical Research in Toxicology, a monthly journal.

8 Apr 2010

Toxicology News and Research

Latest Toxicology News and Research

First-of-its-kind conference on personalized medicine for pediatric patients

miRNAs may generate new insights on cancer and possible future treatments

Caliper Life Sciences introduces Quantum FX stand-alone microCT system for preclinical imaging

Phase II study: Hepatitis C patients receiving ANA598 bid plus SOC attain undetectable levels of virus

New p53 knockout rat model improves timelines for carcinogenicity screening

VisEn Medical expands FMT imaging platform

TruthAboutGardasil.org: Governments need to suspend HPV vaccinations/programs

InterMune reports Phase 1b MAD study results of RTV-boosted danoprevir in HCV patients at 45th EASL

Study: Circadian’s anti-cancer therapy reduces tumour growth in animal models

Cequent Pharmaceuticals commences toxicology study of CEQ508 tkRNAi-based therapeutic candidate

UALR researcher receives federal grant to track estrogen-mimicking compounds in consumer products

3M Drug Delivery Systems grows its product portfolio in Asia’s pharmaceutical industry

Current screening methods for FOBT are often not appropriate

UA Superfund Research Program to study contaminated dust, water and health issues

Dual evacuation following noxious gas leak

Researchers may be one step closer to slowing the progression of Alzheimer's disease

NIAID funds second study of Aeolus Pharmaceuticals' AEOL 10150 as potential countermeasure to GI-ARS

Hunter Valley cancer cluster report to be made public

Triclosan antibacterial found in soap in the spotlight

Potential toxicity of zinc nanoparticles in sunscreen products

Forensics And Toxicology eBook

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

Toxicology News and Research

Latest Toxicology News and Research

Forensics And Toxicology eBook

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

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