Toxicology News and Research

Latest Toxicology News and Research

Scientific evidence links high levels of copper and iron to age-related disorders

With scientific evidence linking high levels of copper and iron to Alzheimer's disease, heart disease, and other age-related disorders, a new report in ACS' Chemical Research in Toxicology suggests specific steps that older consumers can take to avoid build up of unhealthy amounts of these metals in their bodies.

8 Apr 2010

9/11 rescue teams’ lungs still affected and aged by 12 years: say researchers

In a published report in the prestigious New England Journal of Medicine this Wednesday researchers revealed that fire fighters and rescue workers who assisted in the aftermath of the World Trade Center attacks on September 11, 2001 had compromised lung function even seven years after the incident.

8 Apr 2010

Children with FASD show high prevalence of developing epilepsy

Children with Fetal Alcohol Spectrum Disorder show a very high prevalence of developing epilepsy and having seizures, according to a national study by Queen's University researchers.

7 Apr 2010

Ricerca Biosciences, Life Science Partner announce business development agreement

Ricerca Biosciences, a preclinical contract research drug development company, is pleased to announce a business development agreement with Life Science Partner (LSP) Co., Ltd., of Tokyo, Japan. Ricerca offers a unique spectrum of services for the areas of agrochemical registration, environmental analysis and pre-investigational new drug (IND) biopharmaceutical registration.

1 Apr 2010

PolyMedix secures $14M credit facility with Hercules Technology II

PolyMedix, Inc., an emerging biotechnology company focused on developing new therapeutic drugs to treat acute cardiovascular disorders and infectious diseases, has secured a $14 million credit facility with Hercules Technology II, L.P., an affiliate of Hercules Technology Growth Capital, Inc.

1 Apr 2010

Metabolon awarded U.S. patents for metabolomics methods

Metabolon, Inc., the leader in global metabolism through biomarker discovery and analysis, announced today the grant of US Patent 7,682,783 and US Patent 7,682,784 entitled "Methods for Drug Discovery, Disease Treatment and Diagnosis Using Metabolomics". The USPTO awarded the patents to Metabolon on March 23, 2010. The issued claims in the new patents are for uses of metabolomics to identify diagnostic biomarkers for depression and schizophrenia by profiling classes of metabolites in a sample.

1 Apr 2010

LAB Research reports 9% decrease in revenues for 2009

LAB Research Inc., a global Canadian-based non-clinical contract research organization, today announced its fourth quarter and 2009 year-end financial results.

1 Apr 2010

Cell study may yield new treatment strategies for debilitating diseases

A Los Alamos National Laboratory toxicologist and a multidisciplinary team of researchers have documented potential cellular damage from "fullerenes"-soccer-ball-shaped, cage-like molecules composed of 60 carbon atoms. The team also noted that this particular type of damage might hold hope for treatment of Parkinson's disease, Alzheimer's disease, or even cancer.

1 Apr 2010

Researchers evaluate the effect of chemical cocktails on humans and the environment

Throughout our lives we are exposed to an enormous range of man-made chemicals, from food, water, medicines, cosmetics, clothes, shoes and the air we breathe. At the request of the EU, researchers at the University of Gothenburg, Sweden, have looked at the risk of "chemical cocktails" and have proposed a number of measures that need to be implemented in the current practice of chemical risk assessment.

29 Mar 2010

NellOne's lead candidate for skeletal muscle wound healing and myocardial infarction demonstrates potential efficacy

Two key, independent proof-of-concept studies conducted for NellOne Therapeutics, Inc. demonstrate the potential efficacy of the company’s lead therapeutic candidate for both skeletal muscle wound healing and myocardial infarction.

26 Mar 2010

Fluidigm, SABiosciences partner to create pathway-focused gene expression panels for BioMark system

Fluidigm Corporation and SABiosciences (a QIAGEN Company) today announced that they have teamed up to create over 100 pathway-focused gene expression panels validated for real-time PCR analysis on the Fluidigm BioMark™ System for Genetic Analysis. These kits are named the RT² Profiler™ PCR Arrays for the Fluidigm BioMark system.

26 Mar 2010

Clinical Reference Laboratory completes validation testing of DNA Genotek's Oragene-DNA saliva collection kits

Clinical Reference Laboratory today announced that it has completed validation testing of DNA Genotek's Oragene-DNA saliva collection kits and will adopt Oragene-DNA for use with its molecular diagnostic services.

25 Mar 2010

Protein deficiency in Down syndrome patients could contribute to cognitive impairment and congenital heart defects

Conventional wisdom among scientists for years has suggested that because individuals with Down syndrome have an extra chromosome, the disorder most likely results from the presence of too many genes or proteins contained in that additional structure.

24 Mar 2010

Medical imaging benefits outweigh radiation risks, says ESC

Cardiac nuclear imaging and computed tomography angiography (CCTA) still have an important role to play in cardiac disease diagnosis, say experts from the European Society of Cardiology (ESC).

24 Mar 2010

EMA validates InterMune's pirfenidone MAA for IPF

InterMune, Inc. today announced that the company's Marketing Authorization Application (MAA), submitted on March 2 seeking approval of pirfenidone for the treatment of idiopathic pulmonary fibrosis (IPF) in adults, was validated by the European Medicines Agency (EMA). Validation of the MAA by the EMA indicates that the application is complete and that the review process will begin on March 24. The proposed trade name for pirfenidone in both the United States and Europe is Esbriet®.

23 Mar 2010

Breathing diesel exhaust during pregnancy linked with sluggishness in offspring

Breathing diesel exhaust during pregnancy is associated with sluggishness in offspring. Researchers writing in BioMed Central's open access journal Particle and Fibre Toxicology studied the effects of pollution exposure in mice, finding that the offspring of mothers who breathed diesel fumes while pregnant were less likely to show spontaneous movement.

23 Mar 2010

Aureus Pharma to participate in € 118 million BioIntelligence R&D programme

Aureus Pharma, a leading provider of knowledge management solutions to accelerate discovery in the life sciences industry, announces today it’s participation in a EUR118.2 million (USD 160 million) project. The project is the Biointelligence R&D programme designed to promote the use of systemic modeling and simulation tools to exploit biomedical databases to improve research efficiency.

23 Mar 2010

CTSI licenses GeneGo's pathway analysis suite and database searching tool

GeneGo, Inc., a leading provider of software and databases for systems biology, today announced that the Indiana Clinical and Translational Sciences Institute has licensed its pathway analysis suite MetaCore and its database searching tool Eureka.

23 Mar 2010

Atomic layer deposition technique for incorporating "biological functionality" into complex nanomaterials

A team led by researchers from North Carolina State University has published a paper that describes the use of a technique called atomic layer deposition to incorporate "biological functionality" into complex nanomaterials, which could lead to a new generation of medical and environmental health applications. For example, the researchers show how the technology can be used to develop effective, low-cost water purification devices that could be used in developing countries.

23 Mar 2010

Researchers devise simple water test to check for herbicide clomazone

University of California, Davis, scientists are helping rice farmers in Uruguay stop polluting their waterways -- including drinking-water sources and a globally valuable nature reserve.

23 Mar 2010