Ulcerative Colitis News and Research

Latest Ulcerative Colitis News and Research

Researchers trigger natural defense mechanism to alleviate intestinal inflammation

Treating inflammatory diseases of the bowel is extremely challenging: Genes, gut microbes and disrupted immune function all contribute.

31 May 2018

FDA approves first oral medication for adults with moderately to severely active ulcerative colitis

The U.S. Food and Drug Administration today expanded the approval of Xeljanz (tofacitinib) to include adults with moderately to severely active ulcerative colitis. Xeljanz is the first oral medication approved for chronic use in this indication.

30 May 2018

Researchers reveal potent new mechanism of action for treatment of IBD

Professor Akiyoshi Fukamizu's research group of Life Science Center for Survival Dynamics, University of Tsukuba, Eisai Co., Ltd. and its gastrointestinal business subsidiary EA Pharma Co., Ltd. have revealed a mechanism in which an analogue (ER-464195-01) of Eisai's in-house discovered E6007 inhibits integrin activation by dissociating interaction between calreticulin (CRT) and integrin α 4 (ITGA4), suppressing adhesion and infiltration of leukocytes overall.

25 May 2018

Celltrion Healthcare advocates early introduction of biologics for patients to improve clinical outcomes

At the International Society for Pharmacoeconomics and Outcomes Research 23rd Annual International Meeting in Baltimore, Celltrion Healthcare today advocated for healthcare systems to introduce biologics earlier in a patient’s treatment regimen in order to improve clinical outcomes.

22 May 2018

Study: Psoriasis patients taking Humira show no change in aortic inflammation

An antibody used to treat the skin disease psoriasis and other chronic autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease has no effect on aortic inflammation – a key marker of future risk of major cardiovascular events – unlike other antibodies that target different aspects of the immune system.

18 May 2018

Scientists develop integrated system for early diagnosis of diseases using wearable monitors

Researchers from the Wolfson Faculty of Chemical Engineering at the Technion-Israel Institute of Technology have developed an integrated system for early diagnosis of diseases using wearable monitors.

16 May 2018

Study points to new treatments for incurable bowel conditions

Treatments for incurable bowel conditions may be a step closer following the discovery of a key molecule associated with disease flare-ups.

3 May 2018

Single FMT enema produces sustained and significant improvements in cognitive function

A single treatment using an optimized, targeted form of faecal microbiota transplantation (FMT) produces sustained clinical and cognitive improvements, according to the results of a long-term follow-up of patients with liver cirrhosis and hepatic encephalopathy (HE) who had participated in a short-term study.

16 Apr 2018

Analysis does not reveal consistent link between NSAIDs use and exacerbation of inflammatory bowel disease

Contrary to generally accepted belief, a recent review and analysis of published studies did not reveal a consistent association between the use of nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen and exacerbation of Crohn's disease and ulcerative colitis.

5 Apr 2018

University Hospitals study suggests strong connection between IBD and heart attacks

University Hospitals Harrington Heart & Vascular Institute researchers Muhammad Panhwar, MD, and Mahazarin Ginwalla, MD, recently concluded a study of more than 22 million patients that suggests a strong connection between Inflammatory Bowel Disease (IBD) and the development of heart disease and heart attacks.

6 Mar 2018

IQuity launches pioneering RNA-based blood test to diagnose fibromyalgia

Nashville-based data science company IQuity has announced the release of IsolateFibromyalgia™, a pioneering blood test that uses RNA analysis to help health care providers accurately and quickly detect fibromyalgia syndrome.

5 Mar 2018

Inflammatory bowel disease linked to elevated risk of heart attack

An analysis of medical-record data from more than 17.5 million patients found that people with inflammatory bowel disease (IBD) are at elevated risk for a heart attack, regardless of whether or not they have traditional risk factors for heart disease such as high cholesterol, high blood pressure and smoking.

1 Mar 2018

Celgene announces regulatory information about investigational compound for relapsing multiple sclerosis

Celgene Corporation today announced that it has received a Refusal to File letter from the United States Food and Drug Administration regarding its New Drug Application for ozanimod in development for the treatment of patients with relapsing forms of multiple sclerosis.

27 Feb 2018

Impairing rare group of intestinal cells allows gut bacteria to cause inflammation, study finds

The human microbiome - the trillions of tiny bacteria that live in and on our bodies - is emerging as an increasingly important player in health and wellness. But, our co-existence with these organisms is complex, and scientists are learning that even minor changes in this relationship can lead to big problems with our health.

9 Feb 2018

Researchers unravel key molecular mechanism of autoimmune and inflammatory diseases

An international team of researchers led by prof. Savvas Savvides has unraveled a crucial aspect of the molecular basis of autoimmune and inflammatory diseases such as psoriasis, rheumatoid arthritis and Crohn's disease.

18 Jan 2018

New study shows how the immune system regulates gut fungal population

Immune cells that process food and bacterial antigens in the intestines control the intestinal population of fungi, according to a new study from Weill Cornell Medicine scientists.

11 Jan 2018

Precision editing of gut bacteria reduces inflammation in mouse model of colitis

UT Southwestern Medical Center researchers have used precision editing of the bacterial populations in the gut to prevent or reduce the severity of inflammation in a mouse model of colitis.

5 Jan 2018

Researchers design electronic nose to sniff out colon diseases

In much the same way as dogs can be trained to detect some diseases through their keen sense of smell, technology can help create electronic devices capable of performing this same task.

27 Dec 2017

Specific diets may help prevent colorectal cancer in high-risk groups

Colorectal cancer is the most prevalent malignant tumor in Spain. It is known that factors such as diet and intestinal inflammation play an important role in its occurrence, but direct links between nutrients, inflammation and colorectal cancer are poorly described.

21 Dec 2017

Researchers suggest role for MKL1 protein in development of inflammatory bowel disease

Inflammatory bowel disease (IBD), including the two conditions ulcerative colitis and Crohn's disease, results in long-term inflammation of the gut and is associated with dysregulation of the immune system.

13 Dec 2017

Ulcerative Colitis News and Research

Latest Ulcerative Colitis News and Research

Researchers trigger natural defense mechanism to alleviate intestinal inflammation

FDA approves first oral medication for adults with moderately to severely active ulcerative colitis

Researchers reveal potent new mechanism of action for treatment of IBD

Celltrion Healthcare advocates early introduction of biologics for patients to improve clinical outcomes

Study: Psoriasis patients taking Humira show no change in aortic inflammation

Scientists develop integrated system for early diagnosis of diseases using wearable monitors

Study points to new treatments for incurable bowel conditions

Single FMT enema produces sustained and significant improvements in cognitive function

Analysis does not reveal consistent link between NSAIDs use and exacerbation of inflammatory bowel disease

University Hospitals study suggests strong connection between IBD and heart attacks

IQuity launches pioneering RNA-based blood test to diagnose fibromyalgia

Inflammatory bowel disease linked to elevated risk of heart attack

Celgene announces regulatory information about investigational compound for relapsing multiple sclerosis

Impairing rare group of intestinal cells allows gut bacteria to cause inflammation, study finds

Researchers unravel key molecular mechanism of autoimmune and inflammatory diseases

New study shows how the immune system regulates gut fungal population

Precision editing of gut bacteria reduces inflammation in mouse model of colitis

Researchers design electronic nose to sniff out colon diseases

Specific diets may help prevent colorectal cancer in high-risk groups

Researchers suggest role for MKL1 protein in development of inflammatory bowel disease

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Ulcerative Colitis News and Research

Latest Ulcerative Colitis News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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