Particle Analysis Using Flow Imaging Microscopy
Flow Imaging Microscopy (FIM) represents a significant leap forward in particle analysis since it merges the strengths of traditional microscopy and volumetric particle analysis. It provides sharp, detailed images of particles and offers a wide spectrum of morphological data swiftly.
A flow imaging microscope can accomplish three key tasks in just a single instrument:
- Draws a fluid sample through a microscope
- Captures digital images of particles within the fluid stream
- Analyzes and characterizes the particles using a diverse set of measurements
Image Credit: Yokogawa Fluid Imaging Technologies, Inc.
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Flow Imaging Microscopy in Biotherapeutics
Flow Imaging Microscopy (FIM) has become a key player in the field of biotherapeutics. In fact, in 2021 Flow Imaging Microscopy was added to USP <1788> and providing particle images is currently highly recommended for both new products and product resubmissions.
In this eBook we provide:
- An overview of particle analysis
- What FIM is, how it works and the advantages and limitations it poses
- How FIM is applied in the field of Biotherapeutics
- Main considerations to take into account when using FIM for Biopharmaceuticals
Image Credit: Yokogawa Fluid Imaging Technologies, Inc.
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This information has been sourced, reviewed, and adapted from materials provided by Yokogawa Fluid Imaging Technologies, Inc.
For more information on this source, please visit Yokogawa Fluid Imaging Technologies.