Life Science Articles

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High-performance Thin Layer Chromatography (HPTLC) in the Pharmaceutical Industry

High-performance Thin Layer Chromatography (HPTLC) is a robust and cost-effective separation technique employed in the development and analysis of new drugs.

17 Oct 2019

Human Cell Models of the Developing Cortex

Studying human brain development in vivo is difficult. Human cell models such as neurovascular organoids offer researchers unseen insights into the cortex.

17 Oct 2019

Improving Image Resolution Using Nanoparticles

Nanoparticles are small sized particles capable of penetrating vasculature and circulating the body.

15 Oct 2019

Lyophilization (Freeze-drying) in the Food Industry

Freeze-drying, or lyophilization, involves freezing a substance at very low temperatures and then extracting the liquid, creating a solid food item.

17 Oct 2019

Lyophilization (Freeze-Drying) in the Pharmaceutical Industry

The pharmaceutical industry relies on accurate information about structures that can be targeted for research. To effectively study a sample or organism being prepared for analysis, it is useful to retain the integrity of a structure or organism.

24 Oct 2019

Using iPSC Techniques to Study Genetics, Mechanisms & Treatments of Neurodegenerative Disorders

Advances in stem cell technology have enabled us to study the mechanism of disease from cells taken directly from patients in vitro, called human induced pluripotent stem cells (hiPSCs).

28 Oct 2019

Using Phage Display for Antibody Discovery and Development

In phage-display, the gene encoding a bacteriophage protein is replaced with a gene encoding a novel protein. The technique can be used for antibody discovery.

16 Oct 2019

What Can We Learn from the Pan-Genome?

Some decades after the first ever genetic sequence of a living organism was shared, public databases contain several hundred complete bacterial genomes.

15 Oct 2019

What is SATI Gene Editing?

One strategy for studying and understanding biological processes and inherited conditions is gene splicing. The technology lies at the cutting-edge of research into these fields. However, developing efficient in vivo genome-editing that is also universal is a constant challenge.

24 Oct 2019

X-Ray Crystallography in Pharmaceutical Drug Development

Drug development relies on having an accurate knowledge of the structure of organic molecules such as proteins, nucleic acids, and viruses.

28 Oct 2019

Authenticating Complex Herbal Products using Liquid Chromatography

Scientists reviewed the current options for herbal product authentication by chromatographic techniques, to decide on a robust standardized technique.

8 Oct 2019

Confocal Versus Super-resolution Microscopy

Super-resolution microscopy refers to a collection of methods used to increase the resolution of light microscopy, whereas confocal microscopy uses a laser beam to increase the signal intensity from the sample.

11 Oct 2019

Revealing the Molecular Basis of Fragrances using Gas Chromatography

Researchers used multidimensional gas chromatography coupled to serial detection systems to provide deep insights into what makes a pleasant fragrance.

14 Oct 2019

Sensing Oxidative Stress: The ROS-p53 Pathway

Oxidative stress occurs when there are high levels of reactive oxygen species (ROS) in the body, that are capable of damaging lipids, proteins, and DNA.

1 Oct 2019

Interfacial Protein Monolayers are Strong Enough to Hold a Cell

Scientists have shown that a protein monolayer deposited on a liquid-liquid interface between water and a perfluorocarbon solvent can hold hMSCs.

25 Sep 2019

Lipid Metabolism and the Gut Microbiota

This article describes examines the evidence for the role of the gut microbiota in lipid metabolism.

25 Sep 2019

Creating Hypoimmunogenic Induced Pluripotent Stem Cells (iPSCs)

iPSCs may be genetically modified into a hypoimmunogenic state to which the recipient’s immune system will respond less vigorously.

25 Sep 2019

Aqueous Two-phase Systems: Pros and Cons

Aqueous two-phase systems, also known as ATPS, use the properties of the polymer surface and conformation of the materials to partition biomolecules.

25 Sep 2019

Tumorsphere Formulation and Use in Cancer Stem Cell Research

Numerous studies have pointed out that cancer stem cells (CSCs) play an important role in cancer progression, metastasis, relapse, and resistance to therapy. Study of these CSCs can shed light why many existing therapeutic regimens eventually fail.

28 Oct 2019