Life Science Articles

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What is Microbial Memory?

Complex organisms have the ability to remember, meaning that information about past experiences is memorized and can be recalled.

23 Aug 2019

The Immunological Effects of Cannabinoids

The therapeutic effects of cannabinoids have been well-documented, but the effect of cannabinoids on the immune system is still not explored to a great extent. In a recent study, the researchers investigate the potential effects of the cannabinoids on inflammation and the mechanisms behind it.

23 Aug 2019

Metabolomic Profiling of Ricin

Ricin is one of the most toxic substances known to science with an LD50 between 3 and 30 µg/kg in humans.

20 Aug 2019

Spin Labels in Electron Spin Resonance (ESR) Spectroscopy

In ESR, a spin label is added to the target site using cysteine substitution. The sulfhydryl group is then modified with a paramagnetic nitroxide reagent.

20 Aug 2019

2D NMR Spectroscopy: Fundamentals, Methods and Applications

2D NMR differs from 1D NMR by the acquisition stage being separated from the excitation stage. Each method of transfer of magnetization is described here.

20 Aug 2019

Applying Ultrasound to Cell Sorting

Researchers combined of a microfluidics-based single-cell stream with ultrasound acoustics to yield measurable ultrasound echoes of single cells.

18 Jul 2019

Metabolomic Profiling of an Ancient Herbal Medicine using UHPLC

Researchers have used UHPLC to elucidate the medicinal effects of Baccharis grisebachii, an ancient herbal medicine used in Argentina.

18 Jul 2019

What is the Role of Vascular Endothelial Growth Factor?

Formation of new blood vessels can be divided into two processes – vasculogenesis and angiogenesis.

13 Aug 2019

Separating Flavinoids from Plasma Proteins using UHPLC-MS

Scientists have described a method to separate and characterize flavonoids by digesting plasma proteins with protease enzymes and performing UHPLC-MS.

18 Jul 2019

Improving the Safety of Biotherapeutics: Tracing the Protease Inhibitor AEBSF with RPLC-UV

This article describes how RPLC-UV can be used to remove the common protease inhibitor, AEBSF, from antibody preparations for therapeutic applications.

18 Jul 2019

Detecting Cytokines using Intracellular Flow Cytometry

This article describes the validation of monesin in a 1993 study for use in intracellular flow cytometry for the detection of cytokines.

31 Jul 2019

Biosimilar Drugs: Overview and Industry Challenges

Biosimilar drugs are almost identical versions of a medical product or a drug that are produced by a different company to the parent company.

31 Jul 2019

Detecting Extracellular Vesicles in Urine Using a Robust Assay

This article describes how extracellular vesicles are detected and the development of a robust and reproducible assay that overcomes previous limitations.

31 Jul 2019

Using Flow Cytometry to Test Platelet Function in Neonates

In this case study, scientists used flow cytometry as a means of determining platelet function in neonates.

26 Aug 2019

Does the Microbiome Interact with the Human Endocrine System?

Whilst the effect of the microbiome on the digestive system has been studied over the past decade, the understanding of its effect on the endocrine system is less well understood.

13 Aug 2019

A Computational Tool for Column Selection in 2D Chromatography

Matching chromatography columns in 2D liquid chromatography largely depends on the experience of the experimenter. The computational technique eliminates this.

25 Jul 2019

Capturing Circulating Leukemia Cells for Analysis by Flow Cytometry

Researchers have developed a new methodology for the characterization of circulating leukemia cells, and other low-abundance cells, by flow cytometry.

25 Jul 2019