Life Science Articles

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RNAi Applications

This article describes the recent applications of RNAi gene silencing in the fields of genetics, cancer biology and gene therapy.

9 Feb 2018

Cryo-electron Tomography Applications

The applications of cryo-electron tomography (CET), a form of transmission electron microscopy, in microbiology, drug development and diagnostics.

9 Feb 2018

Bottom-Up Approach Overview

This article gives an overview of the bottom-up approach to systems biology, which is used to create tissue-specific simulations for testing drug safety.

8 Feb 2018

Biophotonics Software

This article describes available biophotonics software packages, including FLIMfit, opto-mechanical design software and SHEware.

8 Feb 2018

Life Science Applications of the Bottom-Up Approach

The bottom up approach has been applied to genome building, proteomics as well as modelling and simulation in the life sciences.

7 Feb 2018

G Protein-Coupled Receptors (GPCRs) Overview

This article gives an overview of each G protein coupled receptor (GPCRs) family and the techniques used in research to visualize each family.

31 Jan 2018

Biophotonics in Preclinical Studies

The article describes the applications of biophotonics in preclinical studies, including FRET, biofluorescence and bioluminescence.

30 Jan 2018

Genetic Studies with S. pombe

This article describes how Schizosaccharomyces pombe and Xenopus eggs have been used in genetic studies of mitosis.

26 Jan 2018

GPCR Origin and Diversification

This article describes the origin and diversification of the GPCR families included in the GRAFS classification system.

26 Jan 2018

FRET and Yeast Two-Hybrid Systems Compared

This article compares the applications of fluorescence resonance energy transfer (FRET) and yeast two-hybrid systems.

25 Jan 2018

Fiber Optic Microarray

In several fields including environmental monitoring and biomedical research, the ability to perform accurate measurements is key to a variety of studies.

24 Jan 2018

Applications of Genome-Wide RNAi

This article describes the applications of genome-wide RNA interference, including protocol development, and decoding drug resistance and drug targets.

23 Jan 2018

Applications of Yeast Two-Hybrid Screening

This article outlines the applications of the yeast two-hybrid screening system including examples of scientific studies where the technique has been used.

19 Jan 2018

Conditional Gene Knockout Techniques

This article describes the need for conditional knockout technology, and details the traditional and emerging techniques in this field.

19 Jan 2018

Massive Parallel Signature Sequencing (MPSS)

This article outlines the process of mRNA sequencing and gene expression analysis using MPSS. It also details the applications and limitations of MPSS.

18 Jan 2018

RNAi Mechanism

This article outlines the process of RNA interference (RNAi), the steps involved in the production of siRNA and the precise structure of key proteins.

18 Jan 2018

MPSS and SAGE Compared

MPSS and SAGE are commonly used to quantify gene expression. Both can be used without prior sequence information and have similar applications.

17 Jan 2018

Sample Preparation in TEM

Transmission electron microscopy (TEM) is used to study the structure of small molecules in biology, as well as other particles in material science.

17 Jan 2018

Serial Analysis of Gene Expression (SAGE) and DNA Microarray Compared

DNA microarrays provide rapid screening for a large number of known genes. SAGE cannot facilitate as many samples but can screen uncharacterized genomes.

16 Jan 2018

Two Hybrid Screening: Advantages and Disadvantages

The yeast two-hybrid system is popular due to its flexibility and rapid isolation of interacting proteins; the major drawback is its limited applicability.

16 Jan 2018