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New benchmark of solid-solid free energy differences paves way for better pharmaceutical design

Physical properties (stability, solubility, etc.), critical to the performance of pharmaceutical and functional materials, are known to strongly depend on the solid-state form and environmental factors, such as temperature and relative humidity.

10 Nov 2023

Genetically engineered yeast cells produce natural plant product for schizophrenia treatment

An international team of researchers has demonstrated that genetically engineered yeast cells can produce the natural plant product alstonine, which has shown positive effects in treating schizophrenia.

10 Nov 2023

Revolution by Evolution: Protein Science and its Impact on Drug Discovery

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Mark Abbott, the Managing Director of Peak Proteins, about protein science and its significance in drug discovery.

10 Nov 2023

New research aims to decipher how animals discard half their genes

New research is underway to decipher a fascinating biological puzzle-;how some animals can naturally discard more than half of their genetic information during embryonic development.

9 Nov 2023

Study compiles the most comprehensive list of genetic variants associated with prostate cancer risk

A globe-spanning scientific team has compiled the most comprehensive list of genetic variants associated with prostate cancer risk -; 451 in all -; through a whole-genome analysis that ranks as the largest and most diverse investigation into prostate cancer genetics yet.

9 Nov 2023

Scientists discover kidney-friendly antifungal that evades resistance

In this investigation, researchers produced powerful antifungals of the polyene class without nephrotoxicity.

9 Nov 2023

Genetic melting pot: Study unveils complex admixture in European ancestry populations

In a recent Nature Communications study, researchers revealed that Europeans and European Americans possess a significant subcontinental genetic admixture, challenging the notion that these populations are homogenous. This finding suggests the need to re-evaluate genetic epidemiology studies that may have overlooked the influence of admixture on disease associations and trait heritability in these groups.

8 Nov 2023

Study finds 4% of Icelanders to carry an actionable genotype associated with shortened lifespan

Scientists at deCODE genetics, a subsidiary of Amgen, have published a study on actionable genotypes detected in the Icelandic population and their association with lifespan.

8 Nov 2023

Gamma delta T cells engineered to be more potent and long-lasting against cancer

UCLA scientists have developed a new method to engineer more powerful immune cells that can potentially be used for "off-the-shelf" cell therapy to treat challenging cancers.

8 Nov 2023

New antifungal molecule shows promise in combatting fungal infections without toxicity

A new antifungal molecule, devised by tweaking the structure of prominent antifungal drug Amphotericin B, has the potential to harness the drug's power against fungal infections while doing away with its toxicity, researchers at the University of Illinois Urbana-Champaign and collaborators at the University of Wisconsin-Madison report in the journal Nature.

8 Nov 2023

Can adding RNA sequencing to germline genetic testing improve accuracy and clinical sensitivity over time compared to DNA sequencing alone?

Concurrent sequencing of DNA and RNA to detect the predisposition to hereditary cancer.

8 Nov 2023

Study provides insights into the epidemiology and genetics of clonal hematopoiesis

A comprehensive new study from deCODE genetics, a subsidiary of Amgen, published today in Nature Genetics, provides insights into the epidemiology and somatic and germline genetics of clonal hematopoiesis.

7 Nov 2023

Enhanc3D Genomics expands leadership team with the appointment of Hazel Jones as Chief Operating Officer

Enhanc3D Genomics today announced the appointment of Hazel Jones as Chief Operating Officer.

6 Nov 2023

Individuals with genetic predisposition for physical activity have fewer cardiovascular risk factors

In a study conducted at the University of Jyväskylä's Faculty of Sport and Health Sciences, it was found that individuals with a genetic predisposition for higher levels of physical activity have fewer risk factors for cardiovascular diseases and a reduced risk of developing hypertension, cerebrovascular diseases, and type 2 diabetes.

6 Nov 2023

Telomouse model provides a valuable resource for in-depth aging and cancer research

Researchers introduce the "Telomouse". By making a subtle genetic alteration in standard lab mice, they've made their telomeres, which protect the chromosome ends, more closely resemble those in humans.

6 Nov 2023

Overcoming T-cell exhaustion: A new hope for CAR-T cell therapy

CAR-T cell therapy is a last hope for many patients with blood, bone marrow or lymph gland cancer when other treatments such as chemotherapy are unsuccessful.

6 Nov 2023

New study unveils Foxp3's role in regulatory T cell chromatin architecture

Regulatory T cells are specialized immune cells that suppress the immune response and prevent the body from attacking its own cells.

6 Nov 2023

Synthetic melanin nanoparticles boost wound healing and tissue repair in skin

In a recent study published in npj Regenerative Medicine, researchers discuss the ability of melanin nanoparticles to support wound recovery in mice. The effects at histological and gene levels were explored and confirmed on biomimetic models and human skin explants.

5 Nov 2023

New technique helps 'visualize' osmotic pressure within living embryonic tissues

In order to survive, organisms must control the pressure inside them, from the single-cell level to tissues and organs.

3 Nov 2023

Scientists identify progenitor cells that could revolutionize osteoarthritis treatment

Researchers report that osteoarthritis is caused by the loss of Gremlin 1 (Grem1)-lineage chondrogenic progenitor cells.

3 Nov 2023

Life Science News

New benchmark of solid-solid free energy differences paves way for better pharmaceutical design

Genetically engineered yeast cells produce natural plant product for schizophrenia treatment

Revolution by Evolution: Protein Science and its Impact on Drug Discovery

New research aims to decipher how animals discard half their genes

Study compiles the most comprehensive list of genetic variants associated with prostate cancer risk

Scientists discover kidney-friendly antifungal that evades resistance

Genetic melting pot: Study unveils complex admixture in European ancestry populations

Study finds 4% of Icelanders to carry an actionable genotype associated with shortened lifespan

Gamma delta T cells engineered to be more potent and long-lasting against cancer

New antifungal molecule shows promise in combatting fungal infections without toxicity

Can adding RNA sequencing to germline genetic testing improve accuracy and clinical sensitivity over time compared to DNA sequencing alone?

Study provides insights into the epidemiology and genetics of clonal hematopoiesis

Enhanc3D Genomics expands leadership team with the appointment of Hazel Jones as Chief Operating Officer

Individuals with genetic predisposition for physical activity have fewer cardiovascular risk factors

Telomouse model provides a valuable resource for in-depth aging and cancer research

Overcoming T-cell exhaustion: A new hope for CAR-T cell therapy

New study unveils Foxp3's role in regulatory T cell chromatin architecture

Synthetic melanin nanoparticles boost wound healing and tissue repair in skin

New technique helps 'visualize' osmotic pressure within living embryonic tissues

Scientists identify progenitor cells that could revolutionize osteoarthritis treatment

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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