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Study finds epigenetic signature for obesity susceptibility in human twins

A susceptibility to gain weight may be written into molecular processes of human cells, a Washington State University study indicates.

1 Nov 2023

New gene editing method creates first mice with human-like COVID-19

Researchers have genetically engineered the first mice that get a human-like form of COVID-19, according to a study published online November 1 in Nature.

1 Nov 2023

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

Researchers described an approach to edit the recombination-activating gene 2 (RAG2) locus for therapeutic applications.

1 Nov 2023

From Cells to Drugs: How Cell Painting is Transforming Drug Discovery

In this interview, Jordi Carreras delves into the fascinating world of Cell Painting, a powerful technology gaining momentum in drug discovery. He shares insights into his groundbreaking research, the unique aspects of Phenaros' drug discovery platform, and the synergy between academia and industry.

From ELRIG (UK) Ltd. 1 Nov 2023

UTA biology professor awarded NIH grant for new super-resolution microscope

UTA will soon add a new piece of cutting-edge equipment to its already impressive and growing research armamentarium-;a type of super-resolution microscope (SRM) that allows biologists to see structures within a cell in even finer detail.

31 Oct 2023

Microbial communities growing on plastic debris in rivers could spread disease and antimicrobial resistance

Microbial communities growing on plastic debris in rivers may have the capacity to harbor potentially pathogenic microbes and act as reservoirs of antimicrobial resistance genes, according to a study published in Microbiome.

31 Oct 2023

New project combines traditional methods with metaviromics to study viral outbreaks in wild rodents

When, where, and why do diseases jump from animals to people? A new project will monitor how changing seasons, land use, and human behavior influence viral outbreaks in wild rodent populations, to identify hotspots with high potential for spillover into people.

31 Oct 2023

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

The study reveals that introducing progerin, a protein associated with accelerated aging, into cellular models of Alzheimer's Disease (AD) can hasten the development of AD-related traits. This innovative approach offers a more efficient method for studying AD mechanisms, potentially accelerating the discovery of new treatments.

31 Oct 2023

How next-gen sequencing is changing antibody drug discovery

New study outlines how next-generation sequencing (NGS) and machine-learning methods can revolutionize antibody discovery, particularly against SARS-CoV-2. The research demonstrates that NGS provides greater epitopic and paratopic diversity, enabling more effective identification and prioritization of therapeutic antibodies.

31 Oct 2023

Unbiased proteomic analysis reveals fibroinflammatory landscape of the aging ovary

A new priority research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 20, entitled, "Proteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature."

31 Oct 2023

Using synthetic biology to develop smarter cell therapies for cancer patients

We are embarking on an unprecedented era of therapeutic development enabled by live cell engineering.

31 Oct 2023

Unsupervised genome-wide variant effect predictor based on pretraining of DNA language models

The Genomic Pre-trained Network (GPN), a multispecies model developed to learn genome-wide variant effects.

31 Oct 2023

New MECP2 gene variant identified and characterized in Rett syndrome

Rett syndrome is a rare devastating neurological disorder that primarily affects young girls and manifests as an impaired ability to walk and talk, along with characteristic 'hand-wringing' movements, seizures, and cognitive disability.

30 Oct 2023

UQ's drug discovery facility opens to researchers nationwide after $1.9M funding injection

The University of Queensland's small molecule drug discovery facility will open its doors to researchers from across Australia for the first time thanks to a National Collaborative Research Infrastructure Strategy (NCRIS) funding injection.

30 Oct 2023

UTA bioengineer receives NIH grant to develop high-resolution imaging system to quantify cell tracking

The ability to dynamically track the movement of cells is essential for modeling cellular interactions as they form organs such as the heart. But current microscope technology isn't up to the task of capturing those movements.

30 Oct 2023

Resident Tregs found to remain in certain lymph nodes for a long time

The immune system is fast when it comes to fighting viruses, bacteria and other pathogens. But it also has to know when not to attack - for example, harmless substances such as pollen or house dust, which otherwise trigger allergic reactions.

30 Oct 2023

University of Oklahoma scientist secures nearly $1 million award to advance research in computational genomics

Marmar Moussa, Ph.D., an assistant professor of computer science professor at the University of Oklahoma, has secured a nearly $1 million award from the National Institutes of Health to advance her work in computational genomics.

30 Oct 2023

Short-chain fatty acids produced by intestinal bacteria play role in dendritic cell elongation

Dendritic cells play a key role in the mammalian immune system. These cells are present throughout the human body and are known to capture foreign bodies, i.e., antigens, using extendable "arms" called dendrites.

30 Oct 2023

Study uncovers interplay of lifestyle choices and DNA methylation in gastric neoplasia risk

A new paper in The Lancet eBioMedicine explores whether these changes predict the future risk of stomach tumors and how epigenetic changes interact with environmental and lifestyle factors in this process.

30 Oct 2023

New bivalent vaccine shows promising results against key fish pathogens

The efficacy of a bivalent vaccine against Aeromonas hydrophila (A. hydrophila) and Streptococcus agalactiae (S. agalactiae).

30 Oct 2023

Life Science News

Study finds epigenetic signature for obesity susceptibility in human twins

New gene editing method creates first mice with human-like COVID-19

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

From Cells to Drugs: How Cell Painting is Transforming Drug Discovery

UTA biology professor awarded NIH grant for new super-resolution microscope

Microbial communities growing on plastic debris in rivers could spread disease and antimicrobial resistance

New project combines traditional methods with metaviromics to study viral outbreaks in wild rodents

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

How next-gen sequencing is changing antibody drug discovery

Unbiased proteomic analysis reveals fibroinflammatory landscape of the aging ovary

Using synthetic biology to develop smarter cell therapies for cancer patients

Unsupervised genome-wide variant effect predictor based on pretraining of DNA language models

New MECP2 gene variant identified and characterized in Rett syndrome

UQ's drug discovery facility opens to researchers nationwide after $1.9M funding injection

UTA bioengineer receives NIH grant to develop high-resolution imaging system to quantify cell tracking

Resident Tregs found to remain in certain lymph nodes for a long time

University of Oklahoma scientist secures nearly $1 million award to advance research in computational genomics

Short-chain fatty acids produced by intestinal bacteria play role in dendritic cell elongation

Study uncovers interplay of lifestyle choices and DNA methylation in gastric neoplasia risk

New bivalent vaccine shows promising results against key fish pathogens

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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