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Novel cancer immunotherapy compound degrades an enzyme found in cancer cells and T cells

Researchers in Purdue University's College of Pharmacy are leveraging the dual roles played by an enzyme found in both cancer cells and T cells to create a novel cancer immunotherapy compound.

14 Nov 2023

Study uses cellulose sheets to map body's extracellular vesicles, unlocking disease insights

Study demonstrates the use of cellulose nanofiber sheets for spatial analysis of extracellular vesicles, revealing their geographical heterogeneity in the human body, which could advance the understanding and treatment of diseases.

14 Nov 2023

COVID-19 triggers epigenetic alterations that drive lung damage and fatalities

The COVID-19 disease, due to infection with the SARS-CoV2 virus, became an international pandemic in 2020. To date, more than 770 million people have suffered from the disease and nearly 7 million of them have lost their life.

14 Nov 2023

Traffic emissions disrupt gene expression in human olfactory cells

Exposure to ultrafine particles from traffic alters the expression of many genes in human olfactory mucosa cells, a new study shows.

14 Nov 2023

Cancer stem cells induce macrophage aging, creating conditions for tumor formation

Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of tumors.

14 Nov 2023

Genetic test for antidepressants could save millions and improve patient outcomes

A special kind of genetic test that helps determine the best antidepressant for patients with moderate-to-severe depression could generate substantive health system savings and greatly improve patient outcomes, according to new research from the University of British Columbia.

14 Nov 2023

Neural circuits respond to rapid dopamine surges

Researchers assess the pharmacodynamics of dopamine signaling, brain connectivity/activity, and self-documented 'high' following methylphenidate exposure.v

14 Nov 2023

New study identifies 4,749 key gene clusters that influence progression of 32 cancer types

Researchers at the Mount Sinai Center for Transformative Disease Modeling have released a groundbreaking study identifying 4,749 key gene clusters, termed "prognostic modules," that significantly influence the progression of 32 different types of cancer.

13 Nov 2023

New physical mechanism uncovered for breast cancer invasion

The majority of breast cancers start in the lining of a breast milk duct and, if they remain there, are very treatable.

13 Nov 2023

Discovery of two new enzymes offers easier ways to study and manufacture complex natural chemicals

Slumbering among thousands of bacterial strains in a collection of natural specimens at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, several fragile vials held something unexpected, and possibly very useful.

13 Nov 2023

New hope for TB patients as UNITE4TB launches clinical trial program

Today, UNITE4TB, an international public-private partnership striving to fast-track the development of innovative Tuberculosis (TB) treatments, announced the start of its phase 2B/C clinical trial program with the first participant enrolled at its trial site in Cape Town, South Africa.

13 Nov 2023

Crown Bioscience launches large-scale organoid panel screening platform for accelerated preclinical oncology drug discovery

Crown Bioscience, a global contract research organization (CRO) and JSR Life Sciences company, today announced the launch of its ground-breaking service offering, OrganoidXploreTM.

13 Nov 2023

Life Science News

Novel cancer immunotherapy compound degrades an enzyme found in cancer cells and T cells

Study uses cellulose sheets to map body's extracellular vesicles, unlocking disease insights

COVID-19 triggers epigenetic alterations that drive lung damage and fatalities

Traffic emissions disrupt gene expression in human olfactory cells

Cancer stem cells induce macrophage aging, creating conditions for tumor formation

Genetic test for antidepressants could save millions and improve patient outcomes

Neural circuits respond to rapid dopamine surges

New study identifies 4,749 key gene clusters that influence progression of 32 cancer types

New physical mechanism uncovered for breast cancer invasion

Discovery of two new enzymes offers easier ways to study and manufacture complex natural chemicals

New hope for TB patients as UNITE4TB launches clinical trial program

Crown Bioscience launches large-scale organoid panel screening platform for accelerated preclinical oncology drug discovery

UCI researchers discover gene critical for muscle repair

Researchers identify key factors involved in DNA repair mechanism

New study sheds light on the genes and nutrients that give MAIT cells their fighting power

CÚRAM researchers make breakthrough in cell visualization

New benchmark of solid-solid free energy differences paves way for better pharmaceutical design

Genetically engineered yeast cells produce natural plant product for schizophrenia treatment

Revolution by Evolution: Protein Science and its Impact on Drug Discovery

New research aims to decipher how animals discard half their genes

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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