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Researchers profile new drug combinations to fight antibiotic-resistant bacteria

Antimicrobial resistance – occurring when pathogens can survive antibiotic treatment – is one of the most rapidly emerging global public health threats today.

19 Oct 2023

Virginia Tech researchers develop new drug design framework to fight COVID-19

As the COVID-19 pandemic scattered and isolated people, researchers across Virginia Tech connected for a data-driven collaboration seeking improved drugs to fight the disease and potentially many other illnesses.

19 Oct 2023

How do different organ microbiomes influence neuropsychiatric disorders?

Scientists review existing literature to understand how the microbiome influences neuropsychiatric disorders.

19 Oct 2023

Arterial DNA damage contributes to vascular aging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 19, entitled, "Reduction of double-strand DNA break repair exacerbates vascular aging."

18 Oct 2023

Research reveals new way viruses suppress the CRISPR-Cas immune systems of bacteria

A microscopic discovery will not only enable scientists to understand the microbial world around us but could also provide a new way to control CRISPR-Cas biotechnologies.

18 Oct 2023

Greenspace exposure has positive impact on telomere length, study finds

A new study finds that greenspace – the vegetation in a neighborhood's yards, parks and public spaces – has a positive impact on a key genetic marker associated with exposure to stress.

18 Oct 2023

Lung chip model offers new insights into how radiation damages the lungs

The lung is one of the tissues most sensitive to radiation in the human body. People exposed to high radiation doses following nuclear incidents develop radiation-induced lung injury (RILI), which affects the function of many cell types in the lung, causing acute and sustained inflammation, and in the longer term, the thickening and scarring of lung tissue known as fibrosis.

17 Oct 2023

Strengthening the immune system to fight cytomegalovirus on its own

Some viruses can be dormant throughout a person's life and cause no harm but become dangerous when the immune system is weakened.

17 Oct 2023

SwRI develops unique technology for safe and efficient synthesis of OPNA oxime antidotes

Southwest Research Institute has developed a unique technology (US20230242487A1) that enables the safe and efficient synthesis of organophosphorus nerve agent (OPNA) oxime antidotes.

17 Oct 2023

Researchers study how cells adapt to stressful and complex environments

Imagine the life of a yeast cell, floating around the kitchen in a spore that eventually lands on a bowl of grapes. Life is good: food for days, at least until someone notices the rotting fruit and throws them out.

16 Oct 2023

Lab-grown skin organoids help scientists understand monkeypox infection

Skin organoids offer a powerful platform for drug discovery in the ongoing fight against the virus formerly known as monkeypox.

16 Oct 2023

Bats' genes hold secrets to stronger immunity and longer life

Bats have acquired remarkable traits throughout their evolution. They're the only mammals that can fly, and they live much longer than other animals their size.

16 Oct 2023

Save the environment and protect your skin while doing it – the 'cherry on top'

Researchers discover a sustainable way to repurpose tart cherry waste, harnessing its bioactive compounds for skin care applications. The study reveals that these extracts significantly protect human skin cells from oxidative stress, offering an eco-friendly solution to both food waste and skin health.

16 Oct 2023

Antibiotic-resistant bacteria in Ghana confined to clinical settings

Calland, J. K., et al. (2023). Population structure and antimicrobial resistance among Klebsiella isolates sampled from human, animal, and environmental sources in Ghana: a cross-sectional genomic One Health study. The Lancet Microbe. doi.org/10.1016/S2666-5247(23)00208-2.

16 Oct 2023

Genomic revolution may not be necessary for all species conservation efforts

In the world of threatened and endangered species conservation, the genomic revolution has raised some complicated questions: How can scientists justify assessing species genetic diversity without consulting entire genomes now that they can be sequenced?

16 Oct 2023

Study highlights role of circadian clock component BMAL1 on molecular phenotype of senescent cells

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 19, entitled, "BMAL1 modulates senescence programming via AP-1."

16 Oct 2023

Insilico Medicine to present scientific data on novel anti-cancer assets at major cancer conferences

Clinical stage artificial intelligence (AI) drug discovery company Insilico Medicine ("Insilico") has been invited to present scientific data on its novel anti-cancer assets at three major upcoming cancer conferences -- the European Society for Medical Oncology (ESMO) conference in Madrid Oct. 20-24, 2023; the Society of Immunotherapy of Cancer (SITC) conference Nov. 1-5, 2023 in San Diego; and the San Antonio Breast Cancer Symposium (SABCS) Dec. 5-9, 2023.

16 Oct 2023

Scientists uncover key enzymes involved in bacterial pathogenicity

Gram-negative bacteria cause a variety of infectious diseases in plants and animals alike. Outbreaks of Salmonella and E. coli infections often make headlines due to their severity, and people have to resort to allopathic as well as natural remedies, increasing the burden on the healthcare system.

16 Oct 2023

Is your happiness hardwired? New study dives into the genetics of joy

The study reveals that the genetic basis for happiness is consistent across various age groups and ancestral backgrounds, influencing well-being measures like confidence and calmness. It also finds that this genetic predisposition affects specific brain structures related to psychological and cognitive health.

15 Oct 2023

AstraZeneca announces winners of the 2023 R&D Postdoctoral Challenge

AstraZeneca announced today eight winners of the 2023 R&D Postdoctoral Challenge and agreed to fund their postdoctoral positions at one of the Company’s strategic R&D centres in either Cambridge, UK, Gaithersburg or Boston, US or Gothenburg, Sweden.

14 Oct 2023